"Azathioprine": analogues, price, jagora kuma sake dubawa

Autoimmune cuta - wani rukuni na pathological yanayi a cikinsa akwai wata ƙãra aiki na rigakafi da tsarin da nasa jiki. Domin ya rage na rigakafi da martani, wajabta kwayoyi da kashe tsarin na rigakafi. Wannan kungiyar da kwayoyi ne ba makawa a dasawa su hana dasa kin amincewa. Bari mu dubi irin wannan magani, a matsayin "Azathioprine" analogs da miyagun ƙwayoyi, da kuma umarnin don yin amfani da da fasali.

pharmacological faye hali

A nasa bangare daga cikin miyagun ƙwayoyi "Azathioprine" ya ƙunshi aiki sashi daga cikin wannan sunan. Wannan sunadarai fili ne wanda aka samu daga cikin abubuwa wajibi ne ga kira na DNA da RNA. A cikin jiki, azathioprine ba DNA kira, saboda haka, damuarn cell division matakai a kyallen takarda. Rage aiki na rigakafi da tsarin sa da rinjayar da miyagun ƙwayoyi "Azathioprine" a cikin lymphoid nama.

Kamar wancan akwai hanawa daga cell division matakai da kuma salon salula rigakafi martani. Bayan gabatarwar "Azathioprine" shiri a cikin jiki ne mahaukaci raguwa a yawan phagocytes da kuma rage immunoglobulin kira. Bari mu kara yin nazarin bayanan da: abin da suke da halaye na "Azathioprine" miyagun ƙwayoyi analogues, price, umarnin don amfani.

Pharmacokinetics

Da miyagun ƙwayoyi ne sosai nagarta sosai tunawa a cikin tsari wurare dabam dabam, da kuma ta matsakaicin maida hankali lura bayan kawai 2 hours bayan baka gwamnati. Da miyagun ƙwayoyi ba musamman en ga jini sunadaran ba: ta dauri ga su har zuwa 30%. Domin azathioprine halayyar sakamako farko na rayuwa, ko na farko izinin tafiya a cikin hanta.

Wucewa ta cikin hepatocytes, da miyagun ƙwayoyi ne metabolized da aiki fili - mercaptopurine, da kuma wanda yana pharmacodynamic effects. Halitta kusan gama excreted da bile. A fitsari excreted da ba fiye da 2% na medicament.

alamomi

Shiri "Azathioprine" analogues da wannan aiki abu Ana nuna don amfani a dasawa su hana dasa kin amincewa dauki.

Har ila yau, da miyagun ƙwayoyi ne yadda ya kamata a yi amfani da rheumatological yi da su bi rheumatoid amosanin gabbai da kuma autoimmune cututtuka kamar hepatitis, tsari lupus erythematosus, psoriasis, thrombocytopenic purpura, pemphigus, da kuma waɗansu da yawa.

contraindications

Drug "Azathioprine" An contraindicated a marasa lafiya tare da hypersensitivity da miyagun ƙwayoyi bangaren. Saboda gaskiya cewa da miyagun ƙwayoyi damuarn duk germs na jini, "Azathioprine" An contraindicated a cututtuka na jini (anemia leykotsito- da lymphopenia, thrombocytopenia), kazalika da ciki da kuma reno.

Yi amfani da lokacin daukar ciki da nono-ciyar

The aiki abu ya wuce a cikin ƙirjinka madara da kuma ta hanyar gematoplatsentarny shãmaki. A wannan batun, da yin amfani ba da shawarar a ciki da nono-ciyar. Idan ya cancanta, da nada da miyagun ƙwayoyi ko ta analogues a cikin wannan category na mutane wajibi ne don tantance hadarin daga yin amfani da yin amfani da miyagun ƙwayoyi da yuwuwar cutar da uwa tasa, da tayin. Lokacin da assigning jamiái a lokacin shayarwa kwanan nan soke.

Features na aikace-aikace

Da miyagun ƙwayoyi da kuma ta analogs bukatar da za a yi amfani da hankali a cikin marasa lafiya fama da karambau, kuma a cikin marasa lafiya da rashi na xanthine oxidase.

illa

Babban kungiyar na illa hade da hanawa da bargo aiki, alhakin samar da ja jini Kwayoyin. A da ake ji analogs dauke da azathioprine, da karuwa a cikin size na sel a cikin jini, akan rage leucocyte count, platelet count, anemia.

Ga kashi na narkewa kamar fili da ya fi na kowa illa hada da: rage ci, stool cuta, illa hanta aiki, ulcerative raunuka na gastrointestinal fili. Zai yiwu asarar hepatocytes, bi da wani karuwa a bilirubin ko wasu hanta aiki gwaje-gwaje. A marasa lafiya jurewa tiyata ga sashin jiki transplants da kuma nama iya ci gaba pancreatitis, ulcerative raunuka na ciki, hanjinsu, cigaban mai guba hepatitis.

Rashin lafiyan halayen faruwa sosai da wuya a lokacin da gudanar da miyagun ƙwayoyi "Azathioprine" analogs dangane da shi (msl, "Azathioprine"). Bayyananen ba bayyana, yafi saboda fata rash ko feverish jihohi.

Daga cikin sauran illa kamata a lura da ci gaban na biyu dauke da kwayar cutar matakai a cikin jiki, da bayyanar da murdede da hadin gwiwa zafi, m na koda aikin insufficiency. A wasu lokuta mai tsanani, da miyagun ƙwayoyi "Azathioprine" analogues da wannan aiki abu zai iya sa hemolytic anemia, bada cututtuka daga tsakiya m tsarin. Azathioprine matsayin pharmaceutically aiki abu, wani ɓangare na wannan sunan miyagun ƙwayoyi da kuma ta analogues, yana mai pronounced tasiri a kan tayin (teratogenic da mutagenic effects) da kuma iya sa bayyanar da ƙari matakai da m malignancy. Saboda haka, wajibi ne a bincika saduwa da miyagun ƙwayoyi "Azathioprine" (Allunan) reviews, bayyanai, miyagun ƙwayoyi analogues da zabi da hakkin dabara. Neman gaba, za mu lura cewa a matsayin aiki sashi azathioprine exerts amfani effects a kan hanya na cuta, a cewar alamomi. Wannan yana nuna ba kawai likitoci amma kuma marasa lafiya da kansu.

"Azathioprine" - ma'ana, analogs

Azathioprine - musamman a cikin nasu hanya mai abu da ciwon wani immunosuppressive mataki. A view of Pharmaceutical kasuwar ne ba sosai wakilta shirye-shirye dauke da azathioprine. Analogs "azathioprine" za a iya gabatar a cikin irin wannan magani, a matsayin "Azathioprine".

A miyagun ƙwayoyi ne samuwa a kwamfutar hannu tsari da irin wannan abun azathioprine. The kawai nuance ne kudin da "Azathioprine" da miyagun ƙwayoyi, wanda zai iya a 4-5 sau da kudin na "azathioprine" Rasha samar.

Guba da kuma yawan abin sama

Drug yawan abin sama "Azathioprine" da takwaransa "Azathioprine" bayyana cuta daga cikin gastrointestinal fili, danniya da bargo aiki, kazalika da ƙãra hanta aiki gwaje-gwaje. guba magani a matsayin magani da kanta da kuma ta analogues ne symptomatic, da nufin a speedy kawar da miyagun ƙwayoyi daga jiki. Babu takamaiman maganin guba. Dialysis detoxification hanyoyin su ne tasiri a sashi saboda aiki abu ta hanyar su excreted ba gaba daya.

tsõratar

Da miyagun ƙwayoyi da kuma ta analogs ba da shawarar ga dogon lokacin da amfani. A farkon da jiyya na bukatar m monitoring daga cikin sel na gefe jini, kazalika da kula da na hanta enzymes.

A nan gaba, da kullum iko da iziniNa, gudanar da monitoring nazarin sau daya ko sau biyu a wata.

ƙarshe

Da miyagun ƙwayoyi da kuma ta analogs iya designate kawai wani gogaggen gwani. Kafin shan da nufin zama dole sha cikakken jarrabawa da yiwu gudanar da goyon baya far. Don ƙarin bayani, sa da nada "Azathioprine" shiri umarnin don amfani. Price, analogues na wannan kayan aiki a matsayin wani bangare na kalaman na marasa lafiya. Saboda haka, m kudin na 50 Allunan ne a yankin na 250-300 rubles, da kuma game da analogues aka ambata a sama. Kafin shan dole ne ka auna da "ribobi" da "fursunoni" da kuma fara magani.