Da miyagun ƙwayoyi "Atokor": umurci manual, analogue da kuma sake dubawa

High matakan cholesterol a cikin jini na taimaka wa ci gaban atherosclerosis da kuma cututtukan zuciya da tsari.

Domin dauke sia ragewan magani ta yin amfani da musamman wajen, daya daga wanda ke da miyagun ƙwayoyi "Atokor". Umarnin a kan wannan magani bayyana ta hypocholesterolemic da gipotriglitseridemicheskuyu rawa a rage taro na cutarwa cholesterol da sauran fats a cikin jikin mutum.

Janar halaye

A magani yana nufin hanawa na 3-methylglutaryl-3-hydroxy-CoA reductase. "Dr. Reddy ta dakunan gwaje-gwaje" aka samar da wani India kamfanin.

A shirye-shiryen "Atokor" sashi na iya zama 0,020 da 0,010 g

saki Form

Samar wakili a cikin kwamfutar hannu tsari mai rufi tare da wani farin fim. Allunan extruded a alwatika siffar da biconvex saman a kan daya daga wanda harafin "A" da aka yi amfani, da kuma sauran da aka sanya a matsayin kashi na "10" ko "20".

tsarin

The aiki sashi daga cikin miyagun ƙwayoyi ne atorvastatin, wanda aka wakilta micronized alli trihydrate. A magani "Atokor" sashi da kuma abun da ke ciki na gwada yawa aiki sashi dan kadan daban-daban. Kowane 0,01084 ko 0,02168 g na atorvastatin alli trihydrate daidai 0.01 ko 0.02 g tsantsa atorvastatin.

Madara da sukari, alli carbonate, croscarmellose sodium, polysorbate 80, hydroxypropyl cellulose, lactose dt, magnesium stearate da kwamfutar hannu da kafa tsarin.

A casing film kafa daga hypromellose 15 CPS, propylene glycol, tsarkakakku talc, titanium dioxide.

A wannan duka biyu kashi na nufin "Atokor" abun da ke ciki, da kuma shiryar da su duka.

Allunan 0.01 ko 0.02 g na 10 guda suna kerarre a wani bororo kunsasshen a kwali akwatin.

inji na mataki

Magani wa'azi a kan aikace-aikacen da dangantaka da zabe, m retarders 3-methylglutaryl-3-hydroxy-kofermentaA reductase. Yana da muhimmanci enzyme domin hira da wani fili 3-hydroxy-3-metilglyutarilkoenzima A to mevalonic acid wanda ya biyo baya styrenes da cholesterol.

Idan marasa lafiya na hypercholesterolemia, homozygous heterozygous iyalinmu da kuma wadanda ba iyalinmu type, da kuma gauraye dyslipidemia, da miyagun ƙwayoyi ci "Atokor" taimaka rage total cholesterol, cholesterol barbashi a cikin lipoproteins na low kuma sosai low yawa, triglycerides da apolipoprotein B.

Medicament "Atokor" bayanin da miyagun ƙwayoyi nuna wani yiwuwar m Allunan amfani ƙara da matakin na sterol a lipoproteins tare da high yawa.

A hanta Kwayoyin, kuma triglycerides holesterolovye kwayoyin zama wani ɓangare na lipoprotein abubuwa da ciwon karfi low yawa. Ana aika zuwa ga jini, wanda shiga cikin gefe nama. Daga cikin wadannan mahadi kafa lipoprotein tare da low jikewa iya catalyzed dauki tare da babban dangantaka tsoka mai amsa sigina irin tsarin. Dukkan wadannan abubuwa za su iya bunkasa ci gaban atherosclerotic cuta.

Action Atorvastatin halin da alama kuma m karuwa a yadda ya dace da LDL-tsoka mai amsa sigina gidaje, Munã rage cutarwa cholesterol yawa a dagagge hypercholesterolemia na homozygous hereditary irin.

Na nufin "Atokor" wa'azi yana nuna ikon runtse jini cholesterol matakan da lipoprotein da inhibiting HMG-CoA reductase enzyme. Yana slows saukar da samuwar cholesterol a cikin hanta Kwayoyin, qara yawan tsoka mai amsa sigina tsarin na lipoproteins tare da low jikewa a cikin cell membranes. Wannan kara habaka da kama da catabolism na cholesterol daga lipoprotein kwayoyin na low taro.

Abin da ake amfani da

Medicament "Atokor" User Aikace-aikacen da shawara shan Allunan a primary ãyõyin ƙãra cholesterolemia heterozygous type, na gida da kuma wadanda ba na gida cholesterol taro, gauraye geterlipidemii, ta ƙara adadin jini triglyceride kwayoyin.

Suna gudanar a hade tare da abin da ake ci wa'azi ga ragewan high cholesterol matakin a cikin lipoproteins tare da low jikewa, apolipoprotein B da kuma triglyceride mahadi.

Allunan rage jini taro na cholesterol a cikin LDL cholesterolemia a dagagge homozygous iyalinmu type, a lokacin da ake ci abinci da kuma sauran wadanda ba pharmacological hanyoyin m.

Yadda za a yi

Medicament "Atokor" umarnin don amfani da shawarar da shan kawai bayan da nada wani misali hypocholesterolemic rage cin abinci da lafiya mutum, abin da ya kamata a yi amfani a lokacin far. Dosing aka kafa dabam ga kowane haƙuri, wanda aka lasafta a kan na farko matakin na cholesterol a cikin lipoproteins tare da low jikewa. Yana da muhimmanci a yi la'akari da akayi amfani, da tasiri na far da "Atokor 'shaidarsa.

Yawanci, da farko sashi ne m 0.010 g a lokaci daya kowace rana. A amfani da Allunan ba dogara a kan lokaci na rana da kuma abinci amfani.

A sashi na yau da kullum wajen 0,010 zuwa 0,080 g aka zaba daga cikin na farko lissafin kudi Manuniya na cutarwa cholesterol, da manufa gabatarwa da kuma na sirri tasiri. A matakin farko na aikace-aikace da kuma ta kara maida hankali da miyagun ƙwayoyi ya zama rabin watan duba matakin da jini mai, da kuma daidaita kashi kamar yadda ya cancanta.

Primary hypercholesterolemia da kuma hada hyperlipidemia hali bi da kullum sashi a 0,010 g

Warkewa aiki na faruwa a cikin kwanaki 14, da kuma iyakar yadda ya dace mai yiwuwa ne bayan wata daya. Tsawo amfani sa ya yiwu don kula da warkewa sakamako.

Magunguna "Atokor" a Rasha manual ƙunshi bayani a kan terapiigiperholesterinemii na homozygous iyalinmu irin. Yawanci, wajabta kullum sashi a 0.080 g A wannan amfani ne da rage a LDL cholesterol dabi'u up to 40%.

Features na magani

A Allunan "Atokor 'umarnin don amfani da bada shawara mai karfi kafin fara yin amfani da miyagun ƙwayoyi dole sami hanyar da sakandare karuwa da cholesterol dabi'u. Wadannan dalilai sun hada da ciwon sukari, matalauta lura da ciwon sukari, hypothyroidism, nephrotic aiwatar disproteinemicheskih canje-canje, obstructive cutar hanta. Wannan zai iya hada kara lura da sauran kwayoyi da barasa buri. Kawai bayan yin kawar da sama dalilai, ka shirya don amfani da kwamfutar hannu "Atokor".

Ko kafin far aka yi tabbatar da dalilin da sia daidaituwa tsakanin jimlar cholesterol, LDL cholesterol a cikin HDL cholesterol kuma triglycerides.

Babu bayanai a kan yin amfani da magunguna a cikin yara, yawan, don haka wadannan alluna an ba a nuna da yara.

A lura da tsofaffi da marasa lafiya, wanda shekaru ne fiye da shekaru 60 da, shi ne wani karuwa a jini matakan da aiki wakili bangaren zuwa 40%.

A hali na take hakkin koda aiki ba dole ba ne don daidaita kashi, kamar yadda wannan yanayin ba ya shafar atorvastatinovoe abun ciki a cikin jini da kuma tasiri na ragewan bad cholesterol.

Akwai shaida da cewa yin amfani da wannan aji na kwayoyi sa da ci gaban rabdomioliznoy myopathy da kasa koda aiki a wani m form. A wadannan cututtuka da magani ya kamata a jefar da a lokacin.

Shirye-shirye a kan tushen da atorvastatin ya kamata a dauka a hankali don mutane suke cũtar barasa ko sun hanta da cutar a baya.

A mataki na hanawa na HMG-CoA reductase enzyme iya zama canje-canje a biochemical Manuniya na hanta aiki. Domin dace shigarwa na irin wannan take hakki bukatar gudanar da kimantawa na hanta aiki, sa'an nan watanni 3 bayan shan kwayoyi gudanar da wani rajistan shiga kafin magani.

Drug "Atokor" a kan Rasha umarni ya kunshi bayanai game da wani alama karuwa a jini dabi'u na aiki sashi a marasa lafiya tare da cutar hanta, suka sha wahala daga shan barasa. Wucin gadi ko kuma duka da gazawar da far kõma hanta transaminase aiki a cikin na asali firam. Mutane da yawa marasa lafiya bai warware da yin amfani da miyagun ƙwayoyi a kananan allurai, da kuma wani m halayen sun taso.

A lura iya jin jiri, ci gaba drowsiness, don haka a lokacin da aikace-aikace na alluna marasa lafiya suna haramta don sarrafa kai ko wasu hadaddun na'urorin.

Wa ya kamata ba amfani

A medicament "Atokor" contraindications sun hada da wani karin ji na ƙwarai to kowane sashi na medicament.

Bai dauki al'amarin na m cutar hanta da kuma high kunnawa da transaminase magani enzymes a lokacin da su aiki ne sau 3 fi na sama da iyaka al'ada dabi'u.

Da miyagun ƙwayoyi ba a wajabta wa mata na haihuwa shekaru wanda aka ba ta amfani da isasshen maganin hana haihuwa. Contraindication ne a yanayin haihuwa da kuma shayarwa.

Medicine ba ya bi da yara, kuma matasa a karkashin shekaru 18 da haihuwa.

Saboda gaban madara a cikin abun da ke ciki na alluna 'Atokor "sugar wa'azi a kan aikace-aikace haramta yin amfani da su a wani hereditary rashin ha} uri ga galactose kwayoyin, tare da rashin lactase kuma glucose-galactose malabsortsii.

analogs

Akwai wani babban yawan kwayoyi a kan tushen da atorvastatin. Cholesterol-ragewan miyagun ƙwayoyi rawar "Atokor" umurci manual. Analogs ma iya rage da matakin na bad cholesterol a cikin jini.

Wata irin wannan magani ne wata warkewa ga Basulabe "Atoris", wanda yake shi ne manufacturer na hadin gwiwa stock kamfanin "Krka, Novo mesto." An samar a cikin nau'i na alluna da wani aiki sashi abun ciki na 0.010 g, 0.020 g, 0.040 g

Da miyagun ƙwayoyi ne aka yi nufi ga kashe wani hyperlipidemic yanayin, cikinsa da sigogi zama dole don rage total cholesterol, lipoprotein cholesterol a cikin mahadi da low jikewa, da adadin apolipoprotein da kwayoyin na triglyceride a cikin jini rafi.

Drug bi da mutane da hypercholesterolemia polygenic heterozygous homozygous iyalinmu irin.

Da taimakon "Atoris" miyagun ƙwayoyi qara maida hankali cholesterol a cikin lipoproteins da high jikewa.

Wani Slovene analogue dauke da miyagun ƙwayoyi "Tulip," wanda aka sanya a yanzu "Lek Pharmaceutical Company". Akwai uku dosages film-rufi Allunan: 0.01 g, 0.02 g kuma 0,04 g

Da miyagun ƙwayoyi ne nuna domin kawar da primary siffofin hypercholesterolemic da kuma hada hyperlipidemic yanayin, domin lura da dagagge cholesterol halayya heterozygous da homozygous iyali da irin.

Hakazalika, da wajen dauke Indian magani "Astin", wanda aka samar a yanzu «Micro Labs Limited". Samuwa ne a biyu dosages: a 0,010 g da 0,020 g na atorvastatin.

Da miyagun ƙwayoyi An wajabta a wani ƙara sia abun ciki, a lokacin da shi ba a lura da kyau sakamako na abin da ake ci kuma sauran abubuwan da suka faru.

Indian Manufacturing a medicament "Storvas" dangane da alli gishiri na atorvastatin. Kerarre by "Ranbaxy dakunan gwaje-gwaje Limited" a cikin wani nau'i na kwamfutar hannu mai rufi da daina kai hare hare a biyu dosages: a 0,010 g da 0,020 g

Drug "Storvas" rage babban abun ciki na jimlar cholesterol, LDL cholesterol kwayoyin a, da kuma maida hankali apolipoprotein triglyceride mahadi a cikin primary, da kuma nonmarried heterozygous iyalinmu hypercholesterolemic yanayin, kazalika da gauraye hyperlipidemic cuta.

Magani na rage yiwuwar tsokar zuciya infarction tsokar mai ban mamaki jihar na tsokoki, da shanyewar jiki da kuma canje-canje a cerebral jini ya kwarara. Allunan rage da ci gaban na jijiyoyin zuciya atherosclerotic yanayin.

American takwaransa ne da miyagun ƙwayoyi "Lipitor" aka samar da "Pfizer". An samar a cikin nau'i na alluna mai rufi da harsashi a cikin uku dosages: a 0.010 g, 0.020 g, 0.040 g da miyagun ƙwayoyi ne ma amfani da su kawar da hypercholesterolemic jihohi daban-daban na asali.

reviews

Medicine "Atokor" User Aikace-aikacen bayyana a matsayin nufin da high tabbatar da inganci. Mutane da yawa marasa lafiya da dagagge jini yawa na cutarwa cholesterol, bayan wani hanya na amfani ne samun mafi alhẽri. A dabi'u na jimlar cholesterol, kuma LDL cholesterol an rage wa wata al'ada matakin, wanda rage samu damar bunkasa atherosclerosis, kuma ischemic yanayi.

Da miyagun ƙwayoyi nasa ne da kafofin watsa labarai tare da mai kyau tolerability, amma a wasu marasa lafiya da zai iya haddasa wani bata lokaci ba stool, bloating, jin zafi a ciki, tashin zuciya, bacin. Akwai ciwon kai, gaji da damuwa da barci. Iya ci gaba jerky, asthenic da myalgic yanayin.

A rare lokuta, illa ne bayyana myositis, myopathy, paresthesia, na gefe neuropathy, pancreatitis, hepatitis, cholestatic jaundice.

Allunan zai iya sa anorexia, amai, hepatotoxicity bayyananen, alopecia, pruritic manifestations rashes, rashin ƙarfi, cataracts, hyper- ko da qarancin ruwa da.