"Korvitol": analogues, reviews, umarnin don amfani. Abin da zai iya maye gurbin "Korvitol 50" da "100 Korvitol"?

Zuciya da jijiyoyin jini cututtuka sun fi na kowa. Domin hanzari rage matsa lamba, rage zuciya rate, ya rage da yanayin angina pectoris, migraine, miyagun ƙwayoyi shan "Korvitol". Analogs ma nada sau da yawa ga daya dalili ko wata. Da miyagun ƙwayoyi yana contraindications, saboda haka kafin amfani, shawarci tare da likita.

Saki tsari da kuma abun da ke ciki na miyagun ƙwayoyi

Da miyagun ƙwayoyi nasa ne da beta-shafi. An samar a cikin nau'i na fari Allunan wanda da madauwari spigot, kuma daya mai gefe chamfer hadarin. Samuwa a cikin biyu dosages:

• "Korvitol 100". Ya ƙunshi 100 MG na aiki sashi metoprolol tartrate.
• "Korvitol 50". Yana yana da wani abun da ke ciki na 50 MG na aiki sashi metoprolol tartrate.

Ƙarin sinadaran duka biyu siffofin guda batun da gabatar lactose monohydrate, magnesium stearate, povidone K30, croscarmellose sodium, silicon dioxide, colloidal talc.

A Allunan kunsasshen a aluminum blisters na 10 guda. A kunshin iya zama daga 3 zuwa 10 blisters. Don magunguna kawota umurci manual.

Pharmacology da kuma pharmacodynamics

"Korvitol" ne a cardioselective beta-shafi, wanda ya nuna babu sympathomimetic aiki da kuma ba membrane tabbatar da dorewar Properties. Yana mallaka antihypertensive, antiarrhythmic, antianginal Properties.

Damuarn a cikin wani karamin adadin β1-adrenergic rabe na zuciya da kuma rage samuwar catecholamines kunna Camp daga ATP, rage kwayuka alli ion halin yanzu. Adversely BATM, chrono-, Drome da inotropic tasiri.

TPR a farkon na yin amfani da beta-blockers ƙaruwa, da kuma bayan 'yan kwanaki amfani da kwayoyi koma zuwa ainihin matakin, a lokacin da dogon lokacin da amfani da aka rage.

Antihypertensive dukiyar sa da karu a cardiac fitarwa da kuma kira na wani renin hanawa na renin-angiotensin da kuma tsakiya m tsarin, baroreceptor ƙwarai sabuntawa na aortic baka da kuma ƙarshe rage gefe m tsoma. Yana rage-rage hawan jini a sauran kuma a lokacin jiki neuropsychic load.

A hypotensive sakamako aka samu a minti. Saboda haka, systolic jini da aka saukar bayan minti goma sha biyar bayan a kalla sa'o'i biyu. A sakamakon cimma yana awa shida. Diastolic jini da aka canza sannu a hankali. Karfafawa za a iya cimma kawai bayan makonni da dama da magani.

Antiangialnye ingancin daga cikin miyagun ƙwayoyi m wani karu a tsokar oxygen bukatar saboda da rage a cikin zuciya rate. Rage laulayi da sakamakon na tsokar m innervation, da lambar kuma mai tsanani daga angina harin. Qara jiki jimiri.

Antiarrhythmic Properties aka bayyana a lokacin da cire arrhythmogenic bayyananen rage zumudi da ectopic sinus launi, da kuma hanawa na AV-madugu. Lokacin da manifestations supraventricular tachycardia, atrial fibrillation aukuwa da kuma ganewa na sinus tachycardia hade tare da cututtukan zuciya da kuma hyperthyroidism, da magani na rage zuciya rate. Wani lokaci an tanadi sinus kari. Yana sauqaqa migraine da kuma hana ta aukuwa a nan gaba.

A lokacin da shafi a high warkewa allurai, sabanin nonselective beta-blockers, shi yana da ƙasa da pronounced sakamako a kan gabobin dauke da β2-adrenergic rabe, da kuma carbohydrate metabolism. Lokacin amfani da manyan allurai (a kan 100 MG da rana) yana mai tarewa sakamako a kan duka biyu β-adrenoceptor subtypes.

Metoprolol 95% da ake tunawa daga ciki da kuma hanjinsu. Matsakaicin jini taro lura bayan 1-2 hours. Saboda aiki metabolism lokacin farko da shan miyagun ƙwayoyi bioavailability ne 50%. Bayan m amfani da miyagun ƙwayoyi, ta ƙãra zuwa 70%. Cin abinci kowane lokaci qara bioavailability na 20-40%.

"Korvitol 'alaka da jinin samar da 10%, VD - 5,5 l / kg. Yana wuce ta BBB da plantsentarny shãmaki. Excreted a nono madara a cikin kananan allurai.

Kusan dukkan miyagun ƙwayoyi ne metabolized a cikin hanta. Biyu main metabolites na uku halin da beta-adrenoceptor tarewa dukiya. A metabolism daga cikin miyagun ƙwayoyi daukan bangare isoenzyme na cytochrome P450 (CYP 2D6). Tukar tumbi yana for game da awa 3.5. Da miyagun ƙwayoyi ne excreted a fitsari, da kuma 5% ke canzawa.

koda cuta hana metabolism na metoprolol. Muhimmanci ƙara da bioavailability a cirrhosis. The aiki abu ne ba saki daga jiki a lokacin hemodialysis.

Alamomi ga yin amfani da kwayoyi

"Korvitol" dole ne kawai a yi amfani a kan takardar sayen magani a cikin hauhawar jini. Ana amfani da matsayin monotherapy ko a hade tare da sauran antihypertensive jamiái. A nuni ga yin amfani da shi ne tachycardia, jijiyoyin zuciya da cututtukan zuciya, tsokar zuciya infarction. Sau da yawa amfani da "Korvitol 100", analogues su hana shanyewar jiki da kuma zuciya kari cuta, migraine rigakafin.

contraindications

"Korvitol 50", kuma da miyagun ƙwayoyi a wani sashi na 100 MG ba za a dauka a cardiogenic buga. Contraindication hidima AV-block II kuma III digiri da sinoatrial block. Kada ku riƙi da miyagun ƙwayoyi a wata ciwo matalauta sinus bradycardia. Ban kasance gefe Sistem gazawar da kuma zuciya rashin cin nasara. Allunan ba sha angina, m tsokar zuciya infarction da jijiya hypotension.

Ba za ka iya hada magani "Korvitol 50" (similar to, idan ya cancanta, za su taimake ka zabi da malamin lafiyarka) tare da yin amfani da monoamine oxidase hanawa da kuma igiyar jini injections "Verapamil".

Da miyagun ƙwayoyi ba a nuna a lokacin da nono-ciyar, mutane a karkashin shekara goma sha takwas da haihuwa, da kuma mutane da hypersensitivity zuwa metoprolol, ƙarin abubuwa a matsayin wani ɓangare na wajen.

Tare da musamman hankali Take magani ciwon sukari, Bronchial fuka, emphysema, rayuwa acidosis, na kullum obstructive mashako a siffar. Kawai a karkashin likita dubawa kamata ci magani mutane da gefe jijiyoyin bugun gini cuta, koda ko hanta insufficiency. M, a cikin yin amfani da Allunan 'Korvitol "ya zama marasa lafiya da myasthenia gravis, AV-kawancen na na digiri, kazalika a pheochromocytoma, ciki da kuma hyperthyroidism. Tare da kula rubũta shi a psoriasis da kuma tsofaffi da marasa lafiya.

A lokacin daukar ciki "Korvitol" kwaya rubũta kawai a lokuta da gaggawa bukatar, a lokacin da akwai fetal bradycardia, hypotension, da qarancin ruwa da. A wannan yanayin, da waraka tsari yana da dauki wuri a karkashin kusa dubawa na likita. A nan gaba, kai da incessant dubawa da jariri a lokacin 48-72 sa'o'i bayan ceto.

Metoprolol tasiri a kan yaro ta farko kwanaki na rayuwa ba a sani ba, don haka Ladies da suka yi amfani da miyagun ƙwayoyi, an rika daina nono.

"Korvitol": da amfani da shawarar allurai

A warkewa hanya domin kowane haƙuri ne m da likita, da kuma dogara a kan hanya da cuta. Kawai wani gwani ya kamata a nada da liyafar da kuma sashi daga cikin miyagun ƙwayoyi "Korvitol". Umurnai na amfani (analogs da kwayoyi daga Rasha masana'antun suna da yawa mai rahusa) ya bayyana kawai classic regimens a wasu cututtuka.

Saboda haka, a cikin hauhawar jini da kuma angina amfani da miyagun ƙwayoyi a ciki 100 MG da zarar kullum ko 50 MG sau biyu a rana. Idan ya cancanta, da adadin da miyagun ƙwayoyi ne ta ƙara zuwa 100 MG, dauka kullum sau biyu. Matsakaicin yiwu kullum kashi 200 ne MG.

Aikin cuta daga cikin zuciya, har suka sa zargin tachycardia, da farko liyafar da aka gudanar a wani adadin na 50-100 MG da rana. Wannan adadin iya kasu kashi biyu sau. Kamar yadda ake bukata kullum kashi ya karu zuwa 200 MG.

Don hana migraine miyagun ƙwayoyi wajabta ta 100 MG sau daya a rana, ko 50 ml, a sãfe da maraice. Lokacin da warkewa sakamako aka samu, da kashi ya kamata a rage. Wannan tsari ya kamata a yi sannu a hankali, kuma a karkashin kusa likita dubawa.

Mazan mutane tare da koda cuta da kuma hemodialysis kullum kashi da aka ba rage. A hanta gazawar a kullum adadin da miyagun ƙwayoyi an rage, mayar da hankali a kan haƙuri da yanayin.

A duk cikin sama lokuta, "Korvidol 'da ake amfani da baki, bayan da abinci da kuma wanke saukar da ruwa kadan. Allunan ya kamata a yi lõma ba tare da taban da ake. Idan da miyagun ƙwayoyi ne bugu kowace rana, shan shi ya zo da safe. Lokacin amfani da sau biyu a hannu dauka a sãfe da maraice.

yawan abin sama

Medicine "Korvitol" idan akwai wani yawan abin sama nan da nan daina shan. Alamun cũtar nufin protrude sinus bradycardia, tashin zuciya, juwa ko jiri, rage hawan jini, gag reflex, cyanosis, arrhythmia, bronchospasm, aka rufe da mãgãgi, na ramin zuciya arrythmia.

M yawan abin sama mataki na shirye-shiryen "Korvitol" (analogues a Rasha za ka iya saya a wani kantin magani daga 30 rubles da kuma sama) bayyana matsayin cardiogenic buga, coma, AV-kawancen, asarar sani, cardialgia. Yawanci, da farko alamun eta da yin amfani da kwayoyi fito fili bayan minti 20 - 2 hours bayan gwamnati.

Abu na farko da mãsu haƙuri aka wanke ciki da kuma wajabta kwayoyi adsorbent. Idan akwai wani kaifi digo a cikin jini, mutumin da aka sanya a cikin Trendelenburg matsayi. Idan matsa lamba saukad da zuwa wani mawuyacin matakin da akwai zuciya rashin cin nasara, bradycardia, sa'an nan gudanar intravenously a kan jinkiri na 2-5 minti beta adrenostimulyatorov. A hanya ne da za'ayi kafin a sakamakon tabbatacce. Igiyar jini injections za a iya sanya a kashi na 0.5-2 MG "Atropine sulfate."

Idan da ake so sakamako ba a samu, amfani da kwayoyi kamar "Dopamine," "Norepinephrine", "Norepinephrine" ko "dobutamine". Wani lokacin gudanar 1-10 MG na "Glucagon" ko saita transvenous intracardiac na'urar bugun zuciya. A taron na bronchospasm allura a cikin wani jannayẽnsa beta adrenostimulyatorov. Idan seizures faruwa, sa'an nan sannu a hankali sa allura a cikin wani jannayensa "Diazepam". Hemodialysis a cikin wannan hali ba ya aiki.

illa

Constant liyafar shiri "Korvitol" (kwayoyi) zai iya haifar da wani ɓangare na tsakiya m tsarin ciwon kai, tsoka rauni, wuce kima gajiya, juwa ko jiri, dalili hanawa da shafi tunanin mutum da kuma physiological halayen, paresthesia na hannuwansa da ƙafafunsa. Bayyana ciki, da damuwa, da tsõro, gaji da damuwa da natsuwa. Damu drowsiness, korau mafarkai, rashin barci, da ruɗewa, gajeren lokaci memory hasãra. Asthenic ciwo na iya faruwa.

"Korvitol" da kuma ta analogs iya sa Heart hangen nesa, rashin ruwa da kuma soreness na idanu, akan rage hawaye m samar. A rare lokuta, akwai conjunctivitis, rhinitis. Akwai amo a kunnuwa.

Da miyagun ƙwayoyi iya haifar da matsalar aiki na samfur na zuciya da jijiyoyin jini tsarin kamar yadda sinus bradycardia irin, high zuciya rate, kwatsam matsa lamba raguwa, hypotension, orthostatic hali. A rare lokuta, da rage a tsokar contractility, worsening zuciya rashin cin nasara, arrhythmia, vasoconstriction. Damuwa patency infarction. kardialgiya taso.

Tare da yau da kullum da amfani da miyagun ƙwayoyi aka lura tabarbarewa na gastrointestinal fili, wanda aka bayyana a cikin nau'i na tashin zuciya da amai reflex, zafi a ciki, zawo, bushe baki. Wasu marasa lafiya lura da wani canji a dandani, wata karuwa da muhimmanci ayyuka na hanta enzymes. A rare lokuta, shi bayyana hyperbilirubinemia.

A sakamakon far aka lura dermatological halayen. Wannan psoriasis da ƙarin tsanani, redness, kurji. wuce kima sweating, shi aka lura, alopecia reversible irin da photodermatosis.

Numfashi illa ci karo a cikin nau'i na dyspnea da cunkoso na hanci sassa. Wasu marasa lafiya sha wahala daga nakasa daga 'ya'yan numfashi.

Wani lokaci akwai wani da qarancin ruwa da kuma hypothyroid jihar. Damuwa da marasa lafiya thrombocytopenia, leukopenia, kuma agranulocytosis. Akwai wani alerji a cikin nau'i na itching, amya da rashes. Yana da aka gani ciwon baya (gidajen abinci), nauyi riba, asarar libido, iko.

tsõratar

A amfani da miyagun ƙwayoyi ya kamata gudanar da wani musamman iko da zuciya rate, jini da kuma glucose matakan, musamman a cikin marasa lafiya da ciwon sukari mellitus. A karshen harka, da kashi da aka zaba daidai da juna da cutar.

Ya kamata a koya wa haƙuri Hanyar lissafi na zuciya rate da kuma bukatar koya likita shawara a lokacin da zuciya rate ne kasa da 50 u. / Min.

Idan nada high-kashi (200 MG da rana), rage cardioselective. A marasa lafiya da zuciya rashin cin nasara far ne da za'ayi a lokacin da diyya.

Na iya kara tsanani daga hypersensitivity halayen (tare da aggravated rashin lafiyan tarihi) da kuma rashin sakamako daga cikin gabatarwar al'ada allurai "Epinephrine".

A kan bango da miyagun ƙwayoyi iya worsen bayyanar cututtuka na gefe jijiya wurare dabam dabam.

A yarjejeniyoyin da lura da za'ayi a hankali, rage kashi a magangara mafi ƙasƙanci kwanaki goma. Kada abruptly soke miyagun ƙwayoyi, a matsayin da zai iya haddasa angina da kuma kara jini.

A marasa lafiya da angina kashi da aka zaba don haka da cewa zuciya kudi ne daidai da 55-60 u. / Min da ba ya wuce 110 bpm a lokacin jiki aiki. / Min.

Mutane da lambar sadarwa ruwan tabarau dole san cewa a lokacin far, beta-blockers iya rage samar da hawaye ruwa.

Metoprolol a wasu lokuta fuska da bayyanar cututtuka na hyperthyroidism. Marasa lafiya da thyrotoxicosis contraindicated ba zato karbo daga cikin miyagun ƙwayoyi, kamar yadda wannan zai kawai tsananta cutar.

M marasa lafiya ba zai iya nan da nan gane tachycardia tsokane da qarancin ruwa da. "Korvitol" ƙãru ba, a insulin-jawo qarancin ruwa ko bata dawo daga jini glucose al'ada matakan.

Tsofaffi yayin da shan magunguna kamata kullum saka idanu da koda aiki, kazalika da a marasa lafiya tare da koda insufficiency.

Tsanaki tafii da magani mutum tare da wani depressive jihar, kamar yadda Allunan iya bunkasa mai tsanani da cuta.

A lokacin da magani ya kamata dena tuki da kuma dakatar da ayyukan alaka da natsuwa da hankali, bukata a m amsa.

A lokacin jiyya ya kamata sa rufaffiyar tufafi, saboda miyagun ƙwayoyi zai iya sa photosensitivity.

Abin da zai iya maye gurbin "Korvitol"?

A wasu lokuta, da miyagun ƙwayoyi zai iya sa da dama illa ko kawai ba su zo a kan mataki, saboda haka likita iya musanya "Korvitol". Analogs da irin wannan Properties, samar da wannan warkewa sakamako da kuma an hada da metoprolol tartrate. Su ne quite rare da ake sayar a kusan kowane kantin magani da kuma farashin wasu daga cikinsu kawai isa 50 rubles.

Wadannan suna iya maye gurbin "Korvitol" analogues da wannan aiki sashi:

• "Betalok".
• "Egilok".
• "Metozok".
• "Metoprolol".
• "Serdol".
• "Vazokardin".
• "Lidalok".

Similar effects da wadannan formulations: "Aritel", "Estekor", "Bisomor", "Binelol" "Atenolol", "Kordinorm", "Betacam" "Biol" "Nebilet", "Bisogamma" da sauran kwayoyi.

Lokacin da ya maye gurbin daya miyagun ƙwayoyi zuwa wani, sani cewa da analogue ba ko da yaushe aiki a matsayin nagarta sosai kamar yadda asalin miyagun ƙwayoyi, haƙĩƙa, sun shige jerin gwaje-gwaje da kuma da yawa na gudanar da bincike.

A kudin da miyagun ƙwayoyi, da sake dubawa

Yana da yaushe zai iya maye gurbin "Korvitol" takwarorinsu? Shedu ce cewa yana da wuya a sami wani magani da wannan tsawon lokaci na mataki, duk da cewa samar da yawa kayayyakin dauke da daidai da wannan aiki sinadaran. Medicine sau da yawa shi ne mafi tsada musanya, amma, kamar yadda kwarewa ya nuna, suna kasa ingantaccen takwarorinsu. Reviews nuna cewa "Korvitol" yadda ya kamata lowers jini da kuma hana ci gaban migraine.

50 Allunan na 100 MG kudin 250-300 rubles, wannan adadin a wani sashi na 50 MG ne na tsari na 220 -250 rubles.