Mene ne Addison ta cuta?

Addison ta cutar faruwa a lokacin da matsalar aiki na samfur na adrenal bawo. Wannan cutar da ake bincikar lafiya a maza da mata, mafi yawa tsakiyar-shekaru (30 zuwa 40 years). Yana da wani m cuta, wadda ana rajista a mutum daya da dubu 100. Population. Addison Biermer cuta na iya ci gaba saboda autoimmune matakai, cututtuka (syphilis, da tarin fuka da kuma typhoid adrenals), da kuma a amyloidosis da kuma m siffofin maruran. A 70% da marasa lafiya, cutar na faruwa a sakamakon kasawa a cikin rigakafi da tsarin (antibodies fara kai da jiki ga kasashen waje jikinsu, kai hare hare da kuma hallakar da su). Da hallakar da adrenal bawo Kwayoyin rage-rage kira gluco da mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). Masana kimiyya sun nuna cewa glucocorticoids gwada bambancin biochemical matakai a cikin jiki (shirya jini, insulin taro, an da hannu a cikin tsari na gina jiki kira, lipids, kuma carbohydrates).

Gipokortitsizm sau da yawa lura a marasa lafiya bi da hormones na adrenal bawo. A mafi yawan lokuta, da etiology da cutar har yanzu ya kasance ba a sani ba. Adrenal insufficiency kasu firamare da kuma sakandare. Primary gazawar tasowa a cikin shan kashi na adrenal nama, da kuma na biyu - saboda kasa ruri daga adrenocorticotropic hormone.

Addison ta cuta Alamun

Clinical ãyõyin cuta lalacewa ta hanyar kasawa a cikin kwayoyin da ma'adinai da kuma glucocorticoids. A mafi halayyar siffofin ne da rauni, hypotension, dysfunctional gastrointestinal (tashin zuciya, asarar ci, amai, maƙarƙashiya, zawo wanda sau da yawa maye gurbin). Wasu marasa lafiya hypochlorhydria.

Addison ta cuta yana tare da ƙara irritability ko tawayar yanayi, m ciwon kai da kuma rashin barci. X-ray daga cikin kirji ya nuna wani karu a zuciya size. A electrocardiogram rubũta da ãyõyin hyperkalemia (high potassium maida hankali a cikin jini). Skin pigmentation ba daidai da tsananin cutar, duk da haka, da karuwa ko rage shi a cikin lura da shaida a kan tasiri na warkewa mataki.

Addison ta cutar halin da asalin na sakandare cututtuka kasa mai tsanani. Very wuya da cutar bayyana kanta ba tare da pigmentation (haka sunan "fari Addison"). Babban dalilin wannan cuta ne da tarin fuka adrenals. A rashin dace magani Addison ta cuta da wahala. Clinical ãyõyi ake Littafi: tashin zuciya, amai, zawo, jini saukad da sharply, kara maida hankali potassium a cikin jini. A gefe jini na saura nitrogen qara yawan ja da maikacin jini, haemoglobin. Saboda haka, idan a lokacin da rikicin addisonicheskogo haƙuri ba samar dace taimako, ya mutu tare da ãyõyin koda da kuma cututtukan zuciya.

A mafi muhimmanci awon sigogi ga ganewar asali ne abun ciki na 17-OCS a jini da kuma 17-KS a cikin fitsari, kazalika da rage a jini glucose matakan. Morphological jarrabawa na jini nuna lymphocytosis, eosinophilia da ESR jinkiri.

Addison ta cuta da aka bambanta daga wadannan cututtuka: tagulla da ciwon sukari, pellagra, guba arsenite da Bismut Argentum. Cutar yawanci yana da wani kullum hanya tare da lokaci-lokaci peaking. Addison Biermer cuta mai tsanani ƙaddara da tsanani daga cikin manyan alamun cutar, kazalika da da yawan kwayoyi da suke da zama dole rama domin adrenal insufficiency.