"Zanidip": umarnin don amfani, real marasa lafiya da likitoci da takwarorinsu. "Zanidip-Rekordati": jagora, reviews, analogs

Bisa kididdigar da, game da 26% na manya a duniya fama da cutar hawan jini a kai a kai. Mafi sau da yawa wannan cuta ake dangantawa da wani kayyade predisposition. Duk da haka, akwai sauran dalilai domin ta faru. Wadannan sun hada da kiba, shan taba, da} arfin ci na gishiri, rashin abubuwan da alama bitamin a cikin jiki, barasa zagi, danniya, low jiki aiki, da sauransu.

Ya kamata kuma a lura da cewa, ci gaban da hauhawar jini ya dogara da mutum ta shekaru. Da mazan ya ne, da hakan hadarin irin wannan pathological jihar. A cikin shekaru 40 da shekaru, cutar ne kusan ko da yaushe sakamakon sclerotic jijiyoyin bugun gini raunuka.

janar bayanai

Mafi sau da yawa, likitoci sa marasa lafiya da ganewar asali "da muhimmanci hauhawar jini". Mene ne wannan? Shi ne mai kullum cutar da kuma wani nau'i na hauhawar jini. Ya main asibiti alama abubuwa m da tsawo tadawa na jini.

Canje-canje a wannan cuta na iya zama daban-daban. Duk da haka, da suka da farko da lãbãri a gare jini da kuma zuciya.

Domin inganta haƙuri da yanayin, likitoci bayar da shawarar da wannan miyagun ƙwayoyi a matsayin "Zanidip". Sharhi kan marasa lafiya a kan tasiri na da miyagun ƙwayoyi da za a tattauna a cikin kayan da wannan labarin. Har ila yau, akwai za ka sami bayani a kan yadda za a sami ce magani, idan ya na da wani analogues da illa.

Description, abun da ke ciki, da kuma siffar marufi

A medicament "Zanidip" wa'azi da aka adana a wani kwali cuta da aka dakatar a cikin nau'i na alluna da haske launin rawaya da zagaye da biconvex siffofin da wani alama a kan daya daga cikin bangarorin biyu. Su film-rufi da kuma samun yellowish tint a kan ƙarya.

The aiki sashi na wannan magani abubuwa lercanidipine hydrochloride. Har ila yau, shi ya hada da karin da aka gyara, wanda aka wakilta a matsayin povidone K30, lactose monohydrate, sodium carboxymethyl sitaci, microcrystalline cellulose, kuma magnesium stearate.

Game da fim-shafi halitta, sa'an nan aka hada da abubuwa kamar Opadry Yellow, talc, hypromellose, titanium dioxide, da baƙin ƙarfe oxide rawaya rini, kuma macrogol 6000.

Saya "Zanidip" kwayoyi a bororo fakitoci iya zama, cewa an sanya shi a cikin takarda kwalaye.

Pharmacological halaye na kwayoyi

Shin, ba ka san cewa shi ne mai magani "Zanidip"? Umarnin a kan aikace-aikacen nuna cewa shi ne alli tashar shafi jinkirin. Its aiki sashi ne a racemic cakuda da dextro-da levorotatory stereoisomers. Ya kamata kuma a lura da cewa, shi ne wani wanda aka samu na 1,4-dihydropyridine.

Wannan medicament selectively tarewa halin yanzu na alli ions cikin cardiac Kwayoyin, jijiyoyin bugun gini Kwayoyin da santsi tsoka.

A manufa na ci antihypertensive sakamako daga cikin miyagun ƙwayoyi ne saboda wani kai tsaye relaxant sakamako a kan jijiyoyin bugun gini m tsoka Kwayoyin.

Bisa ga umarnin, bayan samun wata warkewa sakamako na medicament aka samu bayan 5-7 hours. A tsawon lokaci da ta tushe ne kiyaye ko'ina cikin yini.

Saboda babban selectivity daga cikin miyagun ƙwayoyi zuwa jijiyoyin bugun gini m tsoka Kwayoyin, shi ba shi da wani mummunan inotropic sakamako.

To, abin da yake mai magani "Zanidip-Rekordati"? Guide ya furta cewa shi ne metabolically tsaka tsaki magani da cewa ba shi da tasiri sosai a kan abun ciki na apolipoproteins da lipoproteins a jini magani, kazalika da bai canza profile na kitse a mutane da hauhawar jini.

A motsi da miyagun ƙwayoyi

Ina tunawa miyagun ƙwayoyi "Zanidip"? Umurnai na amfani zai sanar da mu cewa bayan samun da Allunan (10 ko 20 MG) baxini lercanidipine kusan gaba daya tunawa daga cikin gastrointestinal fili. Bayan 1.5-3 hours matsakaicin maida hankali miyagun ƙwayoyi a jini jini ya kai wani darajar 3.3 ng / ml ko 7,66 ng / ml bi da bi.

Da rarraba da miyagun ƙwayoyi a kyallen takarda da kuma gabobin daukan wuri quite da sauri. Sadarwa da jini sunadaran ya wuce 98%. Maimaita kashi Allunan na su jari da aka kiyaye.

A metabolism da miyagun ƙwayoyi ne da za'ayi a lokacin farko da izinin tafiya a cikin hanta. Wannan na faruwa da biotransformation CYP3A4. Wannan halitta a yawan metabolites da ba su da pharmacological aiki.

Nuna magani "Zanidip", reviews na wanda aka gabatar da dan kadan ƙananan ta cikin hanjinsu, kuma kodan. Akwai biyu bulan kau na lercanidipine: farkon wanda lokaci ne 2-5 hours da karshe - 8-10 hours.

A canzawa miyagun ƙwayoyi ne kusan ba a gano a cikin tumbi da fitsari.

Mutane da hanta ko koda cuta gina jiki abun ciki na jini da aka rage muhimmanci. A wannan batun, da free sulusi da murabba'i na aiki abu na medicament iya ma ya karu.

Alamomi sami magani

Domin menene za a iya sanya magani "Zanidip"? Reviews na likitoci da rahoton cewa, wannan wakili yadda ya kamata farfado da kanta a muhimmanci hauhawar jini da kuma m zuwa matsakaici mai tsanani.

Contraindications zuwa karɓo allunan

Bisa ga umarnin, da miyagun ƙwayoyi "Zanidip" ba za a dauka a karkashin wadannan yanayi:

• mai tsanani hanta aiki.
• kullum zuciya maye halitta (musamman decompensation mataki).
• sosai koda aiki.
• m angina .
• hade da karfi hanawa isoenzyme CYP3A4 (misali, "ketoconazole", "erythromycins", "itraconazole") da kuma tare da "cyclosporin" da kuma garehul ruwan 'ya'yan itace.
• a lokacin daukar ciki.
• toshewa da jini da ya zo daga hagu ventricle na zuciya;
• lactose rashin ha} uri, lactase karanci da kuma malabsorption ciwo galactose / glucose.
• a lokacin shayarwa.
• kwanan nan da tsokar zuciya infarction (a lokacin da wata daya);
• Mata na haihuwa wanda aka ba ta amfani da dogara wajen na hana haihuwa.
• karkashin shekaru (inganci da kuma aminci ba a kafa).
• hypersensitivity zuwa lercanidipine da sauran dihydropyridine Kalam ko wani gyara na magani.

M shan magani

Drug "Zanidip-Rekordati" matsa a hankali bada shawarar ya dauki mutane tare da mai illa hanta aiki (matsakaici da kuma m), na kullum zuciya nedostatochnostyusindromom sinus, hagu na ramin zuciya kasawa da kuma jijiyoyin zuciya jijiya cuta, kazalika da lokaci daya liyafar "Digoxin" beta-blockers.

Allunan "Zanidip": umarnin don amfani da

A ra'ayi na manyan yawan m events dauke da miyagun ƙwayoyi ne a gudanar da gogaggen ma'aikaci. Yawanci, da aiki da miyagun ƙwayoyi ne shawarar zuwa yi a wani adadin na 10 MG sau daya a rana.

Kwayoyi kamata a da za'ayi a cikin safe, don ¼ hour kafin karin kumallo.

Dangane da warkewa sakamako daga cikin sashi daga cikin miyagun ƙwayoyi a karkashin shawara za a iya ninki biyu, Ina nufin su game da 20 MG. Kara allurai medicament kamata faruwa a hankali. Idan bukata, da karuwa a cikin adadin medicament za'ayi bayan makonni biyu bayan qaddamarwa na far.

Ta yaya ya kamata in yi "Zanidip-Rekordati"? Kada tauna da Allunan. Su kullum lõma da kuma wanke saukar da wani isasshen adadin ruwa.

A tsofaffi Babu sashi gyara ake bukata. Amma lokacin da shan magani ga hãlãyensu bukatar yau da kullum na saka idanu.

A gaban hanta ko koda gazawar ko matsakaici mai tsanani sashi gyara an ba da ake bukata. A farko 'yan kwanaki da miyagun ƙwayoyi gudanar a wani adadin na 10 MG, sa'an nan tare da taka tsantsan kara da kashi zuwa 20 MG da rana.

Idan antihypertensive sakamako ne karfi bayyana, da kayyade sashi ne rage.

illa

Iya sa maras so halayen "Zanidip-Rekordati"? Mabukaci reviews sanar da cewa ci wannan yana nufin su sau da yawa bayyana illa. Me daidai, mu yi la'akari da a halin yanzu:

• Rigakafi da tsarin: Hypersensitivity.
• Zuciya da jijiyoyin jini tsarin: tachycardia, angina, palpitations, aka rufe da mãgãgi, flushing da fuska fata, ciwon kirji, alama raguwa a jini, ciwon zuciya.
• Juyayi tsarin: somnolence, ciwon kai, dizziness.
• Narkewa kamar fili: amai, dyspepsia, tashin zuciya, reversible karuwa a hanta enzymes, zawo da kuma ciwon mara.
• Skin kurji.
• Musculoskeletal tsarin: myalgia.
• Urinary: polyuria.
• Sauran: gefe edema, gajiya, gingival hyperplasia, gajiya.

Bayyanar cututtuka na yawan abin sama

Abin da effects zai bi, idan ka dauki hakan allurai da miyagun ƙwayoyi "Zanidip"? Guide ya bada jerin sunayen da wadannan cututtuka da yawan abin sama: tsokar zuciya infarction, reflex tachycardia, na gefe vasodilation da alama karu a jini, da karuwa a cikin tsawon kuma mita na angina harin.

Don kawar da irin wannan jihohin symptomatic magani.

miyagun ƙwayoyi interactions

Shin yana yiwuwa a hada da wasu kwayoyi magani "Zanidip"? Umurnai na amfani nuna cewa kayan aiki an haramta hada da irin wannan hanawa CYP3A4 (cytochrome P450 na hanta), kamar yadda "Itraconazole" "ketoconazole" da "erythromycin". Wannan shi ne saboda da cewa duk wadannan magunguna kara maida hankali lercanidipine a cikin jini, kazalika da gubar da antihypertensive sakamako.

Lokaci daya liyafar rahoto yana nufin a "cyclosporin" an contraindicated, kamar yadda na iya haifar da wani karuwa a cikin abun ciki na biyu abubuwa a wani haƙuri ta jini.

Lercanidipine da aka haramta don a yi amfani da tare da garehul ruwan 'ya'yan itace. Wannan hade iya haifar da potentiation na antihypertensive sakamako na lercanidipine da kuma hanawa na metabolism.

Ya kamata motsa jiki matsananci hankali yayin da samun "Zanidipa" da irin wannan kwayoyi a matsayin "Astemizole", "Terfenadine" da "quinidine", da kuma ma antiarrhythmics na uku aji (msl, "Amiodarone").

A hade da la'akari medicament da anticonvulsant kwayoyi ( "phenytoin," Carbamazepine ") da kuma" rifamycins "na iya taimakawa wajen rage a jini matakan lercanidipine, sakamakon rage daga cikin antihypertensive sakamako na lercanidipine.

Lokacin da miyagun ƙwayoyi hade tare da "Digoxin" ya kamata ci gaba da saka idanu ãyõyin maye.

Lokaci daya da magani tare da medicament "midazolam" a} uruciyarsa na iya kara absorbability na lercanidipine da kuma rage Absorption Rate.

Masana sun ce cewa "metoprolol" ne iya rage bioavailability na lercanidipine 50%. A wannan yanayin, da bioavailability na "Metoprolol" zauna canzawa. Wannan sakamako ya taso ne daga cikin karu a hanta jini ya kwarara sa da beta-blockers.

Shiri "Cimetidine" a wani sashi na 800 MG da rana ba haifar da gagarumin canji a cikin jini taro na lercanidipine. Amma a da liyafar bukatar musamman da taka tsantsan, tun high allurai na iya kara bioavailability na lercanidipine kuma saboda haka ƙara da antihypertensive sakamako.

Tare da hade da "Zanidipa" tare da "Simvastatin" na farko miyagun ƙwayoyi da za a dauka da safe, da kuma na biyu - da yamma.

A medicament "fluoxetine" yana da wani sakamako a kan motsi na lercanidipine.

Lokaci daya liyafar "Zanidipa" tare da "warfarin" ba zai shafi pharmacokinetics na karshen.

Daga kudaden da za a iya hade tare da diuretics, beta-blockers da ACE hanawa.

Ya kamata mu ma lura cewa ethanol kara habaka da antihypertensive sakamako lekarnidipina.

takamaiman shawarwari

Drug "Zanidip", analogues na wanda aka jera a kasa, ya zama tare da matsananci hankali a cikin mutane tare da sosai koda aiki da kuma jijiyoyin zuciya jijiya cuta, kamar yadda a cikin wannan hali, akwai babban hadarin ya karu mita na angina harin.

Kafin karbar magani ya kamata ko da yaushe a cika zuciya rashin cin nasara a kullum yanayi.

Musamman hankali ya kamata a lura a farkon far, musamman a cikin marasa lafiya da matsakaici da kuma m mataki na hanta insufficiency.

A lokacin jiyya, shi ne kyawawa a hankali gudanar da wani aikin da ke bukatar kulawa ta musamman, ciki har da a hanya management. Wannan shi ne saboda gaskiyar cewa a farkon far kuma a wuce haddi allurai akwai wani hadarin da ya faru na ciwon kai, drowsiness da juwa.

ajiya yanayi, da shiryayye rayuwar da shirye-shiryen da kuma sayar da

A ina zan iya saya kwayoyi "Zanidip-Rekordati"? Analogs daga kudaden da kansa magani sayar a wani ɗakin shan magani. Duk da haka, da suka hašin za'a iya sayansu ne kawai a kan ganin likita.

Ci gaba da wannan magani daga cikin isar kyawawa ga matasa da yara inda zafin jiki ba ya wuce digiri 30.

A shiryayye rai da miyagun ƙwayoyi a karkashin shawara ne shekaru uku. Bayan wannan lokaci, shan magani da aka haramta.

miyagun ƙwayoyi analogues

Shin kana da masaniyar abin da za ka iya maye gurbin kwayoyi "Zanidip"? Analogues na wannan kayan aiki ne quite wuya a samu. Masana sun bayar da rahoton cewa irin wannan dũkiyarsu da kuma aiki da irin shirye-shirye mallaka kamar yadda "Lerkamen" da "Lercanidipine". Shan wadannan magunguna kamata kawai a ga likita shawara.

Drug "Zanidip": reviews da marasa lafiya da kuma kwararru

Yana da matukar tasiri antihypertensive wakili. Wannan da wannan ra'ayi da aka raba ta da yawa likitoci. Mun yarda da su, kuma kusan dukan marasa lafiya shan kwayoyi "Zanidip". Suna da'awar cewa bayan shan magani hãlãyensu markedly inganta. Ãyõyin muhimmanci hauhawar jini ne m kuma matsakaici mai tsanani bar kusan nan da nan.

The kawai drawback na wannan magani ne cewa shan shi sau da yawa sosai sa illa, musamman a kan wani ɓangare na narkewa kamar fili da kuma zuciya da jijiyoyin jini tsarin.

Ya kamata kuma a lura da cewa, mutane da yawa koka game da farashin da miyagun ƙwayoyi ne da muni. Wannan magani ne a cikin adadin 28 Allunan za a iya sayi for 450-500 rubles. Ya kamata a lura da cewa analogues na ce medicament a cikin nau'i na "Lerkamena" da "lercanidipine" ba mai rahusa. Su za a iya saya don wannan farashin.

Masana sun ce cewa kudin na "Zanidip" antihypertensive miyagun ƙwayoyi da cikakken tana biye da ta quality. Yana nuna, kusan duk ya dogon kwarewa a cikin aikace-aikace.