Adrenal hyperplasia - abin da yake da shi? Alamun da kuma lura da cuta

Endocrinologists a su yi ne sau da yawa fuskanci munanan a kodan. Adrenal hyperplasia - abin da yake da shi? Kodan - guda biyu sashin jiki, da adrenal gland suna located kawai sama da ciwon glandular form. Akwai suna kafa zama dole ga jikin mutum hormones (adrenaline, noradrenaline, glucocorticoids, da kuma jima'i). Hyperplasia warware da dama ji ba gani, da kuma wannan ne tare da daban-daban cututtuka.

Adrenal hyperplasia - abin da yake da shi?

Lokacin da adrenal hyperplasia cell nama guda biyu gland progressively yana faɗaɗa, jiki ne ƙwarai ya karu a size, ko da yake yana rike da kansa siffar. Adrenal medullary abu kunshi da haushi.

Yawancin lokaci rinjayar da adrenal bawo hyperplasia, akwai tasowa a pathological tsari. Daban-daban da ƙari sau da yawa bincikar lafiya a medulla.

Yana bayyana cutar a kowane zamani, a mata, maza da yara.

Nakasar adrenal hyperplasia da aka samu a cikin magani mafi sau da yawa. Yawancin lokaci shi daukawa a hereditary, amma kuma iya faruwa a yawan wasu m m ko waje dalilai. Kamar yadda related Pathology da aka gano a cikin marasa lafiya da Cushing ta ciwo (40% na lokuta) ciwo. Wannan ciwo ana bincikar lafiya a tsakiyar da kuma tsufa.

Wannan tsanani Pathology iya ba za a bari. Lokacin da hyperplasia zai lalace samar da hormones zama dole. A mata, sau da yawa yana sa rasa haihuwa. Akwai da dama iri da cutar: nodular hyperplasia na adrenal gland shine yake, nodular, yaxuwa, nakasar da micronodular, kuma hyperplasia na tsakiya kafafu. Mafi sau da yawa wannan cuta yakan faru a cikin mata.

A Sanadin cutar

Sa bayyanar cututtuka bayyana a lokacin da adrenal hyperplasia a yara, maza ko mata zai zama daban-daban. Duk abin da zai dogara ne a kan irin cutar. Hyperplasia yana nufin daya daga cikin jinsunan, shi yana iya zama idiopathic, solteryayuschey, virility.

Lokacin da akwai wani aiki da irin hawan jinni samar da androgens da mineralocorticoids, irin wannan tsari da mummunan tasiri a kan koda tasoshin da kuma fundus, sau da yawa take kaiwa zuwa hauhawar jini ciwo.

Lokacin da solteryayuschem irin hyperplasia ya karu androgen samar, haka akwai wani rashin sauran hormones samar da adrenal bawo. Zo hyperkalemia ko da qarancin ruwa da. A hatsari ne cewa jiki ne dehydrated, rasa nauyi.

Lokacin da virilnoe irin hyperplasia m androgen superaktiven. External genitalia ƙwarai ya karu a size, akwai kuraje, ta ƙara jiki gashi, musculature sosai ci gaba a manyan yawa.

Da farko Pathology fara ci gaba saboda da ƙara mugunya steroid ji ba gani. A samu wani nau'i na cutar tana da yawan key dalilan da ya sa shi ya tashi:

• rayuwa cuta.
• karfi gajiyan.
• Cushing ta cutar.

Nakasar adrenal hyperplasia saboda gaskiyar cewa ko da a lokacin daukar ciki, a lokacin gestation, aikin canje-canje ci gaba. Wani shawara - watsa da cutar a kayyade matakin. Dalilai suka sa bayyanuwar bayyanar cututtuka da cutar: wani matsalar aiki na samfur na hypothalamus da pituitary munanan a kayyade matakin, wani m cin gashin bawo guda biyu gland, gada daga kakanninsu.

nodular hyperplasia

Doctors raba ci gaban adrenal hyperplasia cikin da dama kungiyoyin bisa ga na asibiti hoto, kazalika da irin kwarara.

Nodular adrenal hyperplasia. Wannan nau'i ne hereditary. Mafi sau da yawa bincikar lafiya a cikin tsofaffi, an aggravated tare da lokaci. Lokacin gudanar da ganewar asali saukar da wani halayyar alama - a kan haushi adrenal nodules kafa. Suna iya zama mahara (lobed tsarin) da kuma guda, har zuwa 4-5 cm. Tasowa Cushing ta ciwo. A Pathology ne saboda karfi ruri daga adrenocorticotropic hormone, aka hada a pituitary gland shine yake. Babban fasali na nodular hyperplasia da Cushing ta ciwo sun hada da:

• ciwon kai.
• "Kudaje" kafin idanu.
• convulsions.
• dizziness.
• janar malaise.
• nauyi riba (musamman da ciki, wuyansa, fuska).
• ƙara ci.
• budewa alamomi a kan fata.
• kuraje.
• hirsutism (a cikin mata);
• matalauta farfadowa.
• hyperpigmentation.
• hawan jini.
• m samu karaya.
• ciki.

yaxuwa hyperplasia

A wannan nau'i na prostate hyperplasia bai canja ba da siffar, da karuwa ne sauka a hankali. Amma a lokaci guda sai suka samar da nodules. Gane da irin cutar ne wuya. A misali hanya na diagnosing wani duban dan tayi wani sakamakon. Canje-canje a cikin jiki da ake samu ne kawai a kan MRI ko CT. Sau da yawa ci gaba matasan siffofin, wanda ke faruwa a lokacin da wadannan cututtuka: adrenal hyperplasia a mata sau da yawa take kaiwa zuwa wani karuwa a jiki da gashi, bayyana tsoro harin, hauhawar jini, kiba. A wasu wuraren akwai lalacewa glomerular da kuma harkokin hadin hyperplasia.

A Pathology na idiopathic aldosteronism dogara ne a kan karuwa a aldosterone mugunya. Lokacin da hyperplasia glomerular zone farfado da wadannan cututtuka: hauhawar jini, convulsions, tsoka rauni, ya rage mata motsi, sagè up to inna, ƙishirwa, ya karu da fitsari fitarwa, nighttime urination. Take hakkin sa da karuwa a jini potassium, acidosis. Karuwan jini da aka lura da kullum.

Nodular da nakasar siffofin

Nodular form yawanci progresses a yara da kuma matasa. Yana iya bayyana kanta saboda magudi ko adrenal aiki saboda yawan abin sama na glucocorticoids. Key siffofin na nodular siffar: sababbu mai adibas, tsoka atrophy, pigmentation na fata, cututtuka na ciwon sukari, jijiya lalacewar da zuciya da jijiyoyin jini, osteoporosis. Idan yara bayyanar cututtuka da cutar suna gano a cikin lokaci, da za'ayi a hormonal jiyya, da hangen nesa ne m. Hyperplasia na hagu adrenal gland shine yake - abin da yake da shi? A wannan yanayin, hyperplasia ba a dogara a kan mataki na ji ba gani. Lokacin da sprouting marurai fi 3 cm aiki ake bukata. Laparoscopy aka yi amfani ko kuma bisa ga Fedorov Hanyar lyumbotomicheskim damar zuwa peritoneum a gefen hagu.

Nakasar adrenal hyperplasia (VDKN) ne suka kamu da mafi sau da yawa fiye da sauran jinsunan. A jarirai samu a mita na 1 zuwa 12 dubu. A wannan yanayin, da yaro m rayuwa da kuma bayyanar. Akwai uku main siffofin (wadanda ba na gargajiya, sauki gargajiya, virility da solteryayuschaya.

Mafi na kowa tsari ne solteryayuschaya. Bayyana a 'yan mata da shi kamar yadda ƙarya germofroditizm, boys duhu fata a kusa da Kwalatai (Scrotum), azzakari ƙaruwa a size. Ga marasa lafiya da halin low girma da kuma bayyanar cututtuka irin su drowsiness, tashin zuciya, lethargy, low jini, dehydration, matalauta ci. Cutar dole ne a bi da da farko kwanaki na zama, ko zai yiwu mutuwa.

A gargajiya nau'i ne ba sama da bayyanar cututtuka, amma akwai wani karuwa a cikin kira na jima'i namiji ji ba gani. Idan cutar ba a bi da, karin matsaloli faruwa a mata a jima'i da hankulansu kiwon lafiya.

A ba na gargajiya nau'i bayyana a adult mata da kuma matasa. Babban gunaguni na rashin haihuwa, hailar magudi, hirsutism da kuma kuraje.

Adrenal hyperplasia: janar bayyanar cututtuka

Sau da yawa sosai, yara, maza da mata lura sharewa nau'i na cuta, a lokacin da babu wani pronounced bayyanar cututtuka, a irin haka yana da wuya a gane asali cutar. Nakasar form aka bayyana a cikin yara riga a farko da na biyu a shekara ta rayuwa.

A general, adrenal hyperplasia (abin da shi ne, mun riga ya bayyana) yana da wadannan babban bayyanar cututtuka:

• m jini (low ko high).
• da taki na ci gaba da ciwon sukari mellitus.
• nauyi karuwa.
• bayyananen na osteoporosis.
• numbness na tsokoki, da m atrophy.
• Mata suna "watã-kamar fuska".
• memory hanawa.
• m breakdowns.
• pigmentation.
• budewa alamomi a kan fata.
• disturbances a cikin gastrointestinal fili.
• ragewan na rigakafi.
• nocturnal saki fitsari.
• wuce kima ƙishirwa.
• psychoses.
• rashin haihuwa.
• amenorrhea.
• ba shekaru-dace high girma.
• matafã ba hairline a cikin boko yankin.
• hirsutism.

Maza da mata ya bambanta a cikin asibiti alamun cutar.

magani Jagororin

Dalili na lura shi ne haƙĩƙa da hormonal far. Masana kimiyya ba su yanke shawarar yadda mafi kyau ga aiki a kan adrenal hyperplasia. Jiyya ne sau da yawa a hade. Ga matasa an sanya nufin wanda normalize magana na sakandare jima'i halaye, 'yan mata da aka nuna estrogens da boys - androgens.

Amfani da magani daga wadannan haduwa da glucocorticoids:

• cortisone acetate.
• hydrocortisone.
• dexamethasone.
• prednisolone.

A lokacin da rana da haƙuri na'am 2 ko 3 allurai na hormones (a daidai yawa). Rajista da kuma 5% glucose bayani. Girls, sabanin boys, duk rayuwa yana yin da zama dole shirye-shirye.

Ga kowane haƙuri likita dole ne samu musamman m sanya da magani dabarun (shi duka dogara a kan kwarewa da kuma ilimi). Single far a lura da wannan cuta ba ya wanzu.

Nakasar hyperplasia na adrenal bawo mai tsanani, bi da ta likitoci. Akwai lokuta da cewa al'aurar ba za a iya bambanta a matsayin mace ko namiji. Ga 'yan mata shi ne shawarar roba tare da sababbu siffar da labia. Tuni a cikin shekara ta fari ta rayuwa nuna irin wannan aiki, wani lokacin (a cikin tsanani yanayin) shi ne da za'ayi daga baya. Sa aiki da kuma a cikin siffofin maruran.

Idan jiki rasa gishiri, da mãsu haƙuri ya kamata ya karu da kullum kashi na 1-3 grams. Za a nada a irin haka ne, kuma mineralocorticoid.

Yaxuwa hyperplasia miyagun ƙwayoyi far ba shi da yawa sakamako. Yana ake bukata a irin haka adrenalectomy. M magani da kuma aldosteroma lokacin da a hade tare da yaxuwa hyperplasia. A hasashen shi ne ya fi karfinsu. A batu na zabi ne magani far da zona glomerulosa hadin hyperplasia (idiopathic hyperaldosteronism). Operation a cikin wannan harka - wani matsananci gwargwado.

Zaunanniyar magani IGA - samun spironolactone, shi ne wani antagonist na aldosterone. Har ila yau tasiri ne da miyagun ƙwayoyi eplerenone. Spironolactone ne sau da yawa dauka a hade tare da alli antagonist. Idan cututtuka ba jijiya hauhawar jini, magani da ACE hanawa an haɗa.

A cikin hali na wata liyafar virilization na tabbatarwa kwayoyi akai-akai. Idan da irin adrenal hyperplasia tana nufin wani virilizing, ya zama alƙawari na cortisol. Ana iya amfani da a matsayin intramuscular allura. Kashi tsince likita. Ga mazan yara na iya amfani da prednisolone.

Idan babu dace magani, da hyperplasia iya haifar da ci gaban da cutar Kona ko Cushing ta cutar. Bayan da ta dace ganewar asali magani ya kamata a fara nan da nan.

ganewar asali da cutar

Adrenal hyperplasia - abin da yake da shi? Yadda za a gane asali cutar? Nodular da kuma yaxuwa hyperplasia gano a cikin shakka daga instrumental da dakin gwaje-gwaje da bincike. A bincikowa hada da: haƙuri duba, jiki da jarrabawa, da na asibiti jarrabawa, radiological jarrabawa ko Magnetic rawa Dabarar, radionuclide scanning. Bisa ga sakamakon kiyasta darajar, da kuma nau'i na biyu adrenal gland. Radioimmunoassay yi awon bincike. M a cikin fitsari da kuma jini cortisol. Don tantance hormonal matsayi, rike-nasaba immunosorbent kima. Wani lokacin shi wajibi ne su gudanar da muradinta na huda.

Bisa ga sakamakon bincike da likita fallashi na bincike da kuma sanya mafi dace Hanyar magani.

Hyperplasia manya: abin da ya yi?

Yawancin lokaci Hyperactivity na adrenal bawo ana bincikar lafiya a tasowa, amma da alamu da cutar bayyana a manya. adrenal hyperplasia a mata ne halin da wani babban ci gaban da pubic gashi, zurfin murya, kuraje, zafi a baya na kai, nocturnal seizures, matalauta ciyar, ya karu jini, adrenal ciwo.

Idan ka sami kanka a cikin wadannan cututtuka, kada ka yi kokarin gano da kanka. A cikin wadannan lokuta, bã ku taimakon, kuma jama'a magunguna. Gaggawa magance likitoci. Wajibi ne a hormonal magani. Yawancin lokaci, mata da irin wannan ganewar asali ba da shawarar shirya ciki. A lokuta da dama, ko da aka haramta ba haihuwa. Wani lokaci mafi kyau warware matsalar - da cikakken kawar da waxannan cututtukan da koda, da kuma duk ta appendages.

rigakafin

Mene ne adrenal hyperplasia - shi ne musamman bukatar sanin waɗanda ma'aurata suka shirya haihuwar da yaro da kuma a cikin iyali da suka (genetically) da lokuta na nakasar hyperplasia. Don Allah a koma zuwa jinsi - gwani, masani kwararru. Ga masu rigakafin cutar bukatar yin ganewar asali perinatal (tsawon lokacin da jariri ne har yanzu tasowa, da kuma shi ne a cikin mahaifar Uwa). A farko trimester ciki ne da za'ayi chorionic villus daukan samfur. A cikin rabi na biyu na bukata bincike na ruwar, wanda zai ƙayyade matakin na ji ba gani.

Option - IVF. A wannan yanayin, za ka iya yin na farko kayyade bincike na jam sel kafin su hadu.

A lokacin gestation mata kamu da hyperplasia ya zama karkashin m dubawa na wani likita a kai a kai wuce duk ake bukata gwaje-gwaje. Ya kamata a cire daga rayuwar duk yiwu guba abubuwa kuma sakamakon radiation.

Ga masu rigakafin adrenal hyperplasia taka muhimmiyar rawa da kuma nunawa gwaje-gwaje da za a yi a wani jariri. Domin bincike shi wajibi ne ya dauki jini daga capillary (a wuri zaba domin huda diddige yaro).