Hemolysis - menene wannan? Hemolysis na jini, m hemolysis

Halakar ja jini jikin tantanin kuma tukar tumbi da haemoglobin a cikin jini da aka kira hemolysis. Wannan tsari na faruwa a saboda da mataki na musamman abu haemolysin (hemolysin). Konkoma karãtunsa fãtun ja jini Kwayoyin iya fara kasa saboda gubobi ko bakerialnyh samar antibodies. A halin yanzu, likitoci sun gano wani yawan irin wannan tsari. Suna classified dangane da hanyar ilimi, daga batu a wadda ta wuce daga haddasawa da cewa zai iya sa shi.

Sanin cewa hemolysis - halakar ja da maikacin jini, a cikin abin da haemoglobin aka saki daga gare su, da yawa ba su sani ba, wanda shi ne dalilin da ya sa wannan zai iya faruwa.

Abubuwan da kai zuwa ga halaka da erythrocyte membranes

Don magance da tsari, shi wajibi ne don gano, wanda shi ne dalilin da ya sa halakar ja jini Kwayoyin iya fara. Dangane da abin da ya faru inji, wadannan iri hemolysis.

1. Natural. Wannan tsari faruwa ci gaba a cikin jiki, shi ya fara a karshen saba rai sake zagayowar daga kowane daga cikin ja da maikacin jini, da rayuwa game 100-130 kwana.

2. Chemical. Yana faruwa a lokacin da ja da maikacin jini za a fallasa abubuwa da za a iya soke membrane lipids. Wadannan sun hada da daban-daban Alkali, alcohols, ethers, chloroform. Alal misali, hemolysis aka furta idan wani mutum yana guba manyan kashi na acetic acid.

3. Biology. erythrocytes daina kai hare hare a fara kaskantar saboda daukan hotuna hemolytic poisons, msl, a sakamakon cizon kwari ko macizai. Har ila yau, nazarin halittu hemolysis auku saboda da transfussion na m jini.

4. zazzabi. Lokacin da misãlin jini erythrocyte kankara lu'ulu'u suna kafa. Bayan ta thawing suka karya da harsashi.

5. Mechanical. Lokacin da girgiza wani jirgin ruwa da jini, ko da ta yin famfo na'ura wanda artificially goyon wurare dabam dabam, lalace erythrocytes.

6. The osmotic. Idan ja corpuscles fada a ranar Laraba, inda da osmotic matsa lamba zai zama m fiye a cikin jini, su fashe. Shi ne dũkiyõyinsu da ake amfani da ganewar asali na anemia ko hanta cututtuka.

Sanadin hemolysis

Don gane da abin da kuma lokacin da ya je ja da maikacin jini, dole ne ka fahimci lokaci kamar hemolysis. Wannan halaka harsashi da maikacin jini na iya faruwa intracellularly ko tasoshin. Yawancin wadannan iri hemolysis sa da cututtuka daban-daban. Amma kuma da erythrocyte membrane za a iya halaka su da wucin gadi nufin a dakin gwaje-gwaje da karatu.

Idan ya zo ga intravascular hemolysis, da harsashi na ja corpuscles a cikin akwati an lalace a aiwatar da jini wurare dabam dabam. Wannan na faruwa a cikin wadannan cututtuka:

- hemolytic anemia ciki har da autoimmune.

- paroxysmal nocturnal hemoglobinuria.

- paroxysmal sanyi agglutinins cuta.

Har ila yau vntutrisosudisty hemolysis iya nuna guba hemolytic poisons.

Halakar erythrocytes auku a cikin sel a cikin hanta, saifa ko bargo. An lura a irin wannan matsalar lafiya kamar yadda microspherocytosis hereditary, autoimmune anemia da kuma thalassemia. Sanin game da haddasawa da kai ga halakar ja jini cell membranes, ya bayyana cewa hemolysis - shi ne mai hadarin gaske. Ba zato ba tsammani, wadannan kwayuka tafiyar matakai an sau da yawa tare da kara girma daga cikin baƙin ciki, kuma hanta size.

A bayyanar cututtuka na hemolysis

Idan jikin mutum ya fara karya saukar wuce haddi na ja da maikacin jini, sa'an nan lura da su ne kawai a lokacin da m Hakika na cutar. Mafi na kowa bayyanar cututtuka na uncontrolled halakar erythrocytes ne waɗanda: yellowness integuments ko pallor, rage matsa lamba, m bugun jini. A ãyõyi kuma sun hada da gaggautsa kusoshi da gashi.

Amma da yawa ba ko da quite sau da yawa m cewa suna da da hemolysis na jini. Mẽne ne za su iya koya quite da hatsari, wani likita jarrabawa. Amma tare da m hanya sau da yawa da tashin zuciya, juwa ko jiri, gajiya, wani rauni da ko da zazzabi.

Hemolysis zai iya sa anemia, wanda bi da bi ne mai hadarin gaske saboda shi zai iya sa high jini clots ko kai ga cholelithiasis.

Shin akwai dalilin tsoro?

Akwai lokuta inda marasa lafiya suna tilasta su sake kwato dakin gwaje-gwaje gwaje-gwaje saboda gaskiyar cewa hemolysis faru. Mutane da yawa suna fara kalle da ãyõyin hatsari cututtuka, mai guba raunuka ko kawai guba. Amma a mafi yawan lokuta babu wani dalilin damuwa, saboda erythrocyte membrane iya halaka saboda inji dalilai. Alal misali, sau da yawa jini Kwayoyin iya lalace a aiwatar da jini a wani gwajin tube, idan ma bakin ciki allura ko nas da sauri Firaministan jini. Erythrocytes doke kan tube bango da kuma fashe. A sakamakon haka, da jini zama ruwan hoda, da kuma ware shi a cikin wani centrifuge zama ba zai yiwu ba.

A irin haka ne muka ce cewa akwai wani m hemolysis. Shi ne ba wata cuta amma a sakamakon rashin iya jini Samfur ta ajiya, kai ko da tanadin. Ga wani abin dogara bincike na bukatar wani daban-daban rabo daga jini. A haƙuri a cikin wannan hali, kafin maimaita wani kima rika sha ruwa mai tsabta.

m hemolysis

Amma idan hanyar da Lalacewar ja jini Kwayoyin - ba da mãma kuskure, muna magana ne game da wani tsanani matsalar. Mafi sau da yawa m hemolysis faruwa ne ta jini a lokacin da akwai m ja Kwayoyin. A sakamakon haka, wannan take kaiwa zuwa kunnawa da najumla tsarin, coagulation da humoral rigakafi.

Abu ne mai sauki gano, saboda a wannan yanayin hemolysis - wannan shi ne babbar matsala, wadda ba a bayyana asibiti hoto. Idan da mãsu haƙuri ne m, zai koka da ciwon kirji, ciwon baya, ciwon mara, agitation, ji na zazzabi, tachycardia. Matsa lamba da za a rage. Idan hemolysis fara a lokacin aiki da za'ayi a karkashin janar maganin sa barci, da ãyõyi zai zama zub da jini da raunuka, kuma idan akwai wani urinary catheter - za a fitsari duhu ja ko baki.

dakin gwaje-gwaje da bincike

gwaje-gwaje da ake dauka don tabbatar da ganewar asali. Idan haƙuri hemolysis, sa'an nan da sakamakon jini gwaje-gwaje za a saukar thrombocytopenia, hemoglobinemia, bilirubinemia, Munã rage da damar da anticoagulant da fibrinolytic. A fitsari, da mãsu haƙuri zai yi irin wannan darajar matakan creatine zai auku hemoglobinuria, hyperkalemia, rage adadin fitsari har ta da cikakken rashi.

A kan tabbatar da cewa zũciyõyinsu jini Kwayoyin suna hallaka, m magani ya kamata a gudanar.

magani

Tsaya hemolysis zamani magani quite wani karfi. Idan aka sa ta jini, da warkewa matakan da ya kamata a yi niyya ga lõkacin fatara daga tashin jiko na ja jini Kwayoyin. Bugu da kari, shi ne muhimmanci a fara da transfussion na musamman mafita da za su iya hana ci gaban hypovolemia, koda hypoperfusion. Har ila yau plasmapheresis shi za'ayi da nufin kau da ake zagawa da free haemoglobin a cikin jini. A saboda wannan dalili, a mafi yawan lokuta da allura wakili "Heparin" intravenously via infusomats. Ya taimaka wajen jimre wa m hemolysis da miyagun ƙwayoyi "Prednisolone". All alƙawura ana sanya dangane da haƙuri da yanayin, shi ne kuma muhimmanci a san tsawon lokacin da suka wuce ya fara hemolysis. Wannan taimaka likitoci yanke shawara a kan magani dabara, saboda a wasu lokuta ya zama dole rike gaggawa hemodialysis. Alal misali, shi wajibi ne, idan an gano cewa haƙuri ta m na koda gazawar.

Magani a matsayin hanyar hemolysis

A amfani da wasu magunguna erythrocytes kuma za a iya a hallaka su. Ta wajen haddasa hemolysis na jini, sun hada da dama kungiyoyin da kwayoyi.

1. Analgesics: "Amidopyrine", "asfirin", "Antipyrin".
2. Diuretics: "Fonurit", "Diakarb".
3. Nitrofurans "furadonin", "Furazolin".
4. Sulfonamides "Sulfalen", "salazosulfapiridina", "salazopiridazina", "Sulfapiridazin".
5. Hypoglycemic kwayoyi, "Tolbutamide", "Hlorpropamid".
6. Anti-magungunan, "Isoniazid", "Efes".
7. Malariya kwayoyi, "Quinine", "Akrikhin", "Primaquine."

Lokacin amfani da wadannan jamiái za a iya lura hemolysis. Wannan ba ya nuna wani matsaloli, ya bayyana a matsayin mayar da martani ga magani.