Nalidixic acid: amfani da magani

An sani cewa kwayoyin sune cututtukan cututtukan cututtuka da cututtuka masu yawa. Don kawar da jikinsu, amfani da maganin maganin rigakafi. Akwai magungunan maganin da dama da aka umurce su akan kwayoyin cuta. Ɗaya daga cikin irin wannan magani shine acid nalidixic. Yana da aiki mai yawa na kwayoyin cutar antibacterial. Misali ɗaya ne allunan Nevigram. Wannan miyagun ƙwayoyi ne na quinolones, ƙungiyar pharmacological wani wakili ne na antimicrobial. Kafin farawa magani, wajibi ne a gudanar da gwaje-gwaje don gano magunguna da kuma gwada lafiyarsa zuwa magani.

Nalidixic acid - mece ce?

Babu shakka kowa ya san kwayoyi masu dauke da kwayar nalidixic. An yi amfani da wannan abu shekaru da yawa a magani kamar maganin antimicrobial da antiparasitic. Nalidixic acid, kamar yadda aka sani, tana cikin ƙungiyar quinolone. Magunguna sun hada wadannan abubuwa tare da kwayoyi antibacterial. Nalidixic acid an classified a matsayin magani na roba, wato, an halicce shi a cikin yanayin binciken. Yana da haske foda foda wanda ba za'a iya narkar da shi cikin ruwa ba. Babban aikace-aikacen acid shine magani. Yana da wani ɓangare na wasu maganin rigakafi.

Ayyukan nalidixic acid

Don sanin ko wane irin cututtuka na nalidixic acid ke amfani dasu, yana da muhimmanci don nazarin tsarin aikinsa. Babban magungunan wannan magani shine maye gurbin kwayar cuta na kwayan cuta da hallaka su. Hanyar aikinsa ita ce ta dakatar da kiran DNA daga microorganisms ta hanyar polymerization. Shirye-shirye na sinadarin Nalidixic aiki a kan kwayoyin Gram (-). Su na da tasiri don yaki da kwayoyin halitta na Halitta na Proteus, E. coli. Saboda haka, suppressing kumburi cututtuka, wanda ake sa ta wadannan kwayoyin.

Sakamakon magani yana dogara ne da haɗuwa a jiki. A cikin kananan allurai, shi yana da bacteriostatic sakamako, watau, shi damuarn DNA kwafi. Hannun ƙwayoyi na miyagun ƙwayoyi suna rinjayar kira na gina jiki da RNA. Sabili da haka, amfani da dogon lokaci ko kula da Allunan a cikin manyan allurai yana haifar da aiki na kwayoyin. Ya kamata a tuna cewa Gram (+) microorganisms da anaerobes ba su da tasiri ga acid nalidixic. Sabili da haka, kafin a sanya shi, dole ne a gudanar da binciken binciken bacteriology na kwayoyin halitta (fitsari, jini) da kuma gudanar da maganin kwayoyin halitta.

Indications ga acid nalidixic

Yawancin cututtuka masu ciwon kumburi da ake amfani da su a cikin nalidixic acid. Umarni a cikin kunshin tare da miyagun ƙwayoyi, tare da daidaitaka ya nuna abin da cututtuka abu mai aiki ya kai ga. Duk da haka, yana da daraja a la'akari da cewa waɗannan cututtuka ba a koyaushe sukan sa Gram (-) flora ba. Sabili da haka, idan miyagun ƙwayoyi ba shi da amfani, dole ne a maye gurbin shi tare da wani magani bayan kwana 3. Ƙananan ƙonewar kodan shine babban bambance-cututtuka da aka tsara wacce ake amfani da kwayar nalidixic. Yin amfani da kwayoyi da ke dauke da wannan abu ba abu ne kawai ba a cikin nephrology, amma kuma a wasu bangarori na magani. Alamomin farko sune:

1. Cystitis. Kullun da mafitsara ya fi sau da yawa ta hanyar E. coli da proteus, sabili da haka, shirye-shirye na rukuni na quinolones an tsara su da suke da tasiri sosai a kan waɗannan microorganisms.
2. Pyelonephritis. Kumburi na ƙananan tubules na da kyau sosai tare da shirye-shirye na nalidixic acid, musamman ma a cikin karamin lokaci.
3. Sanin ganewar cututtuka na urinary tsarin. A wannan yanayin, ana ba da kwayoyi kafin aikin magudi da aiki.
4. Magungunan otitis mai tsanani.
5. Cholecystitis.
6. Cututtuka na inflammatory na lokacin farin ciki da ƙananan hanji (enterocolitis).
7. Urethritis da prostatitis.

Haka kuma ana iya tsara kwayoyin Nalidixic don sauran cututtuka da Gram (-) microorganisms ke haifarwa.

Waɗanne shirye-shirye sun ƙunshi nau'in nalidixic acid?

Akwai wasu kwayoyi da ke dauke da acid nalidixic. Dukansu suna da wannan aikin da alamomi don amfani. A wasu lokuta, kashi na babban abu mai mahimmanci abu ne daban. Sunan daban-daban da farashin wadannan kwayoyin sun dogara ne akan asalin ƙasar da kamfanin da ke samar da magani. Mafi shahararren wakilin shine miyagun ƙwayoyi Nevigram. Wannan magani yana da yawancin analogues. Daga cikin su, magunguna: "Negra", "Nalid", "Cystidine", "Vintomilon", "Urogram" da sauransu. Duk waɗannan kwayoyi suna da irin wannan sakamako a jiki.

Nalidixic acid: umarnin don amfani da miyagun ƙwayoyi

Dole ne a dauki shirye-shiryen dake dauke da acid nalidix a sashi na mita 500 a kowace rana sau 3-4. A mafi yawancin lokuta, wannan adadin mai aiki yana kunshe a cikin kwamfutar hannu daya ko capsule. Tare da ƙonawa mai tsanani, za ka iya ɗauka 1000 MG 4 sau a rana. Yara ya kamata su lissafta sashi (60 mg / kg nauyin jiki).

Contraindications da sakamako masu illa

Kamar yawancin kwayoyi masu cutar antibacterial, an haramta yawan kwayar nalidixic a cikin matan da suke cikin farkon shekaru uku na ciki da nono. Har ila yau, waɗannan magunguna ba za a iya amfani da su ba daga yara a ƙarƙashin shekara 2. Daga cikin wasu contraindications, ƙananan rufi da kuma nakasa marasa lafiya an bambanta.

Hanyoyi masu lalacewa sun haɗa da rushewa daga fili (flatulence, nausea, vomiting), dizziness, rashin lafiyan halayen. Dole ne a yi amfani da tsinkayen nalidixic acid ga mutanen da ke fama da kwayoyin halitta (cututtukan Parkinson, epilepsy, ONMI).