"Nimesulide" kwayoyi. Umarnin don amfani, real takwarorinsu

Pain - shi ne wani nau'i ne na yunkurin na jiki zuwa jawo hankalin hankalin da mutum, kira domin taimako. Saboda haka ba daidai ba cewa wani abu "a cikin Danish mulkin", da kuma albarkatun na jiki bai isa ya gyara matsalar, muna bukatar goyon baya daga waje.

Mai amfani da pharmaceutical kasuwar na Rasha Federation gabatar daruruwan kwayoyi don taimakawa mutane jimre da matsalolin da ciwon. All magunguna daban-daban abun da ke ciki, ikon yinsa, da kuma tsarin ba da tasiri. Daya daga cikin mafi tasiri ne kwayoyi daga cikin rukuni na ba-steroidal anti-kumburi kwayoyi. Daga gare su ne dakatar da Allunan "Nimesulide".

Tsari da kuma abun da ke ciki

Zagaye Allunan da lenticular siffar. A launi na iya zama rawaya kodadde ko kawai rawaya. Babban aiki bangaren - wani abu Nimesulide a kowane hannu - 100 MG. Daga mai lamba za a iya kira ƙarin microcrystalline cellulose, sitaci (masara), sodium sitaci glycolate, colloidal silicon dioxide.

Bugu da kari, da miyagun ƙwayoyi da aka miƙa wa masu amfani a cikin nau'i na powders domin dakatar "Nimesulide." Abun da ke ciki shi ne kamar abin da na Allunan, kowane 100 MG sachet babban aiki bangaren.

pharmacodynamics

Nimesulide selectively damuarn cyclooxygenase-2, cyclooxygenase-1, ta sakamako ne ga mai yawa karami har. A wannan batun, da hanawa da prostaglandins kira lura tsokani kumburi dauki. Duk da haka, samuwar prostaglandin-type kullum nimesulide exerts kawai m sakamako, sakamakon kadan na biyu manifestations na narkewa kamar tsarin.

Bugu da kari, da tasiri mataki na nimesulide bayyana a cikin hanawa daga cikin samuwar free radicals. Duk da haka, da matakai na hemostasis da phagocytosis ba wahala sakamakon wannan abu. Ginshikai na anti-mai kumburi sakamako exerted medicament bautarka babba sarari, kuma da ikon kashe a saki myeloperoxidase (a dama kumburi cututtuka zai iya sa nama lalacewa, shi ne daya daga cikin mafi m bincike halaye nuni da hadarin m na ciwon zuciya ko bugun jini).

Alamomi ga yin amfani da

Wide isasshen ikon yinsa, daga cikin miyagun ƙwayoyi "Nimesulide". A abin da ya sa wannan magani? Saboda da miyagun ƙwayoyi yana a kan mutum hadaddun sakamako - antioxidant, analgesic, antipyretic kuma anti - sa'an nan shi ake sa tare da wani yawan kumburi cututtuka. Tasiri miyagun ƙwayoyi da kuma a gaban osteoarthritis (na kullum hadin gwiwa cuta da fari an hallaka articular guringuntsi), tendinitis (kumburi agara da nama degeneration), bursitis (kumburi da mucous bags, Marinjãyi a gidajen abinci).

Good sakamakon ya nuna "nimesulide" da magani daga rheumatoid amosanin gabbai, karin-articular rheumatic cututtuka. Nasarar yaki da cututtuka da cewa suna tare da kumburi tafiyar matakai. Popular sau da yawa, "Nimesulide" kwamfutar hannu amfani a gynecology, da magani daga raunin da ya faru daban-daban asalin. Marasa lafiya ce da tasiri kawar da zafi a lokacin postoperative fi.

Contraindications "nimesulide"

Tun da medicament tana nufin wani rukuni na zamani National gamuwa Square, shi yana da quite wani m jerin contraindications. "Nimesulide" (daga abin da yakan taimaka wa magani - An tattauna a baya) kada kai mutane tare da hypersensitivity zuwa wani bangaren a cikin abun da ke ciki. Babu magani gudanar wa waɗanda marasa lafiya da tarihin bayyana hepatotoxic halayen da kuma hypersensitivity halayen kamar yadda rhinitis, bronchospasm, urticaria (tare da asfirin ko wasu NSAIDs wakilan kungiyar).

Contraindications don yin amfani da medicament ne to da wani erosive-ulcerous raunuka na narkewa kamar tsarin, da hali wajen samar da zub da jini na wani asalin (t. E. Bambance-bambance a aiki na jini clotting).

Medicine "Nimesulide" wa'azi haramta marasa lafiya da na koda, hanta, cardiac insufficiency. Marasa lafiya da "asfirin" fuka, barasa da miyagun ƙwayoyi dogara, kuma kada ku yi da miyagun ƙwayoyi.

Kada rubũta magani a kuma waɗannan lokuta, idan haƙuri ne ta ƙara yanayin jiki ko wasu mura-kamar bayyanar cututtuka suna lura. Bugu da kari, shi ne unacceptable dauki "Nimesulide" yara, ciki da kuma lactating mata.

Zai yiwu gefen halayen "nimesulide"

Aikace-aikace na medicament iya haifar da wani yawan illa daga daban-daban gabobin da kuma tsarin na jikin mutum.

Mafi na kowa halayen an rubuta ta narkewa kamar tsarin, kuma su suna bayyana ta tashin zuciya, amai, zawo, flatulence, da kuma ci gaban gastritis. Kadan sau da yawa faruwa gastrointestinal na jini, ulcers har perforation. Lokaci-lokaci za ka iya ji game da dyspepsia, stomatitis, ciwon mara.

Zai iya sa "nimesulide" gefen mataki da hepatobiliary tsarin, mafi sau da yawa bayyana a cikin ƙãra hanta enzyme matakan, akalla - a cikin ci gaban da hepatitis (ciki har da fulminant ..), Cholestatic jaundice.

A dauki na zuciya da jijiyoyin jini tsarin iya ce, idan akwai wani kwari Yunƙurin a jini, marasa lafiya da wuya damu game zuciya palpitations, hemorrhage, flushing, jini tsalle.

Urinary tsarin iya amsa su bayyanar edema (ba sau da yawa), da wuya - urinary riƙewa, hematuria, dysuria. Sosai da wuya ta iya ci gaba na koda gazawar, interstitial nephritis, oliguria.

Zai yiwu halayen na CNS aka fi bayyana da dizziness, malaise, asthenia. Kadan sau da yawa za a iya ji game da ciwon kai, somnolence ci gaba (kama hypnotic barci), Reye ta ciwo (encephalopathy), hypothermia (yanayin jiki da rage kasa da matakin da ake bukata domin kula da al'ada metabolism). Lokaci-lokaci za ka iya ji game da irin wannan halayen "Nimesulide", kamar yadda nervousness, juyayi, yãyen mafarki.

Game da lymphatic tsarin da hematopoietic tsarin, "Nimesulide" (Umarni, ma'aikatan jinya da sake dubawa tabbatar da wannan bayanai) na iya wuya tsokane anemia, eosinophilia, duk da haka kasa kusantar wajen samar da thrombocytopenia purpura pantsitopenicheskaya.

Da wuya, amma za ka iya ji game da rayuwa disturbances (hyperkalemia), rigakafi da tsarin (hypersensitivity, anaphylaxis), da gabobin da hangen nesa da (Heart hangen nesa, clouding na filayen), na numfashi, mediastinum (dyspnea, bronchospasm, fuka-haren). Akwai halayen da fata da kuma subcutaneous nama (sweating, itching, dermatitis, urticaria, erythema, sosai da wuya - mai guba epidermal necrolysis, Stevens-Johnson ciwo).

dosing da kuma aikace-aikace kewaye yanayin

Adult marasa lafiya Allunan "nimesulide" rika daukar daya a lokaci (100 MG) kullum sau biyu. Shi ne fin so yin haka bayan wani abinci da sha da ruwa da yawa don magani. Idan wani foda ga dakatar, sa'an nan da abinda ke ciki na daya sachet aka diluted a 100 ml na ruwa. Matasa a kan shekaru 12 da haihuwa babu bukatar canza kashi, da kuma yara wannan miyagun ƙwayoyi zuwa sama haramta. A cikin hali na lura da tsofaffi da marasa lafiya a kashi gyara ba a yi.

Domin mutanen da fama da hanta insufficiency, creatine yarda a cikin kewayon 30-80 ml / min., The sashi ne ba daidai ba. Idan nuna alama an saukar da (30 ml / min ko kasa.) - haramta sami medicament.

Waɗannan su ne babban shawarwari ga liyafar da miyagun ƙwayoyi "Nimesulide". A sashi da aka zaba minimally tasiri, kuma ga guntu yiwu lokacin, wanda zai rage girman hadarin illa. Matsakaicin hanya na far tare da yin amfani da "Nimesulide" kada ya wuce kwana 15.

Wuce kima sashi: Bayyanar cututtuka, Jiyya

Shan kwaya "Nimesulide", shi wajibi ne ya yi riko da allurai da shawarar a cikin umarnin ko zaba ta hanyar halartar likita. Kai gwamnatin medicament da kuma (ko) ta uncontrolled amfani zai iya haifar da yawan abin sama. A mafi akai-akai lura da wadannan cututtuka: tashin zuciya da amai, zubar da jini, gastrointestinal fili, drowsiness, lethargy, hauhawar jini (hawan jini), hanawa na numfashi aiki, m na koda gazawar.

Jiyya a harka na yawan abin sama symptomatic, an goyon bayan hali. Maganin guba nimesulide a halin yanzu bace. Idan tun overdosing ko shan wani babban kashi na medicament ba shige fiye da 4 hours, da mãsu haƙuri ne a asibiti na ciki da lavage shawarar liyafar absorbent (msl, kunna carbon a cikin adadin 60-100 MG ga ya fara tasawa) da kuma wasu iri osmotic laxative miyagun ƙwayoyi.

Cikin dukan zamanin da magani ya kamata a hankali da sanya idanu kiwon lafiya kwararru aiki hanta da koda. Bayani game da yiwuwar kau na nimesulide daga jiki da hemodialysis ba samuwa. Saboda babban mataki na miyagun ƙwayoyi dauri ga sunadaran tilasta diuresis ba tasiri.

musamman umarnin

"Nimesulide" don saya takardar sayen magani daga Pharmacy wanda ba a bukata, duk da haka, ya kamata a dauka tare da taka tsantsan. Kauce wa layi daya aikace-aikace na medicament da wani ba-steroidal anti-kumburi jamiái, analgesics bawa. Tare da ci gaba da bayyanar cututtuka da marasa lafiya, hanta lalacewar halayyar (tashin zuciya, amai, anorexia, duhu fitsari) ko kara da matakin na hanta transaminases aikace-aikace "nimesulide" ya kamata a yi watsi. Idan akwai wani zazzabi ko mura-kamar bayyanar cututtuka, far ya kamata a daina amfani da nan da nan.

M wa marasa lafiya ya zama cewa a cikin layi daya da "Nimesulide" shan magunguna cewa kara hadarin gastrointestinal ulcers da kuma zub da jini. Kariya wajabta magani ga mutanen da suke fama daga ulcerative colitis ko Crohn ta cuta, ulcers ciwon tarihi na tsofaffi da marasa lafiya.

Mutane masu bukatar daukar "Nimesulide" tare da asfirin a cardiac allurai dole ne a sanya hade far da gastroprotectives.

Da amfani da "Nimesulide" (ko kuma wani NSAID) a cikin manyan yawa da kuma a kan wani dogon lokaci take kaiwa zuwa wani kananan karuwa a hadarin thromboembolic hatsarori (bugun jini, tsokar zuciya infarction, da sauransu. N.).

Marasa lafiya da daban-daban zuciya da jijiyoyin jini matsaloli "Nimesulide" tsarin iya nada kawai idan da ana tsammanin amfani wuce hadarin illa.

A medicament yana da wani sakamako a kan mataki na platelet aiki. Wannan bayani yana da muhimmanci ga marasa lafiya fama da hemorrhagic diathesis. Mai tsanani raunuka na fata mafi sau da yawa ci gaba a lokacin dogon lokacin da amfani "nimesulide". Da zarar fata rashes bayyana, ya zama appreciable lalacewar mucous membranes ko wani tsayayyen manifestations na rashin ha} uri, magani far ya kamata a katse.

Da amfani da "Nimesulide" mata masu ciki zai iya fararwa rufe jijiya bututu da shi ake bukata, rage girma daga ruwar. Zai yiwu ƙãra hadarin intrauterine na jini, weakening na aiki, bayyanar edema. Domin wadannan dalilai, mata masu a lokacin farko da na biyu awo na ciki liyafar "Nimesulide" ba da shawarar.

Yana dole ne ya zama amsa ga wannan tambaya na ko za mu iya dauka cikin "Nimesulide" lokaci guda kuma barasa, shi ne bayyananne: irin mai hade da ba a halatta!

analogs

Karkashin analogs "nimesulide" yana nufin kwayoyi daga NSAID kungiyoyin dauke a matsayin babban aiki sashi nimesulide (price for su za oscillate a kamar wannan fanni amma dan kadan a kasa da shi). A mafi sani da kuma fiye wajabta likita ma'aikatan analogs hada da miyagun kwayoyi "Naiz" (gel, kwamfutar hannu, dakatar), "Nimesil" (powders) "Niemiec" (Allunan) 'nimulid "(gel, Allunan, dakatar da Allunan for tsotsa) .

All analogs mallaka isa dace da kuma sanya magance tare da fadi da kewayon cututtuka, mai kumburi saka hali.

price kewayon

Prices for kansa "Nimesulide" da kuma ta analogs ne kamar guda, ko da yake mun yi la'akari da miyagun ƙwayoyi kudin mafi m ga mai fadi da kewayon saye. Allunan "Nimesulide" (20 inji mai kwakwalwa. A wani fakitin) zai kudin 85-90 rubles da fakitin. A wannan adadin Allunan "Naiza" za kudin 110-140 rubles, "Niemiec" (wato 20 inji mai kwakwalwa.) - a cikin 115-134 rubles. Marufi "nimulid" na 30 kwayoyi halin kaka 180-220 rubles. The girma abun ciki na babban aiki sashi (Nimesulide) a duk analogs guda - 100 MG.

Maimakon Allunan "Nimesulide" (magangara mafi ƙasƙanci kudin) za a iya samu, misali, wata slurry "Naiz" halin kaka 200-300 rubles 60 ml ko "nimulid" - 75-105 rubles ga wannan adadin miyagun ƙwayoyi. Har ila yau, akwai wa mai fadi da kewayon masu amfani da lozenges "nimulid": 20 hannun jari a farashin 130-155 rubles da fakitin.

Zai yiwu mafi tsada nau'i na saki da miyagun ƙwayoyi da nimesulide a matsayin babban bangaren - wani foda 'Nimesil ". 30 bags (kunshin) zai kudin abokin ciniki a cikin adadin daga 560 zuwa 645 rubles.

Domin Topical aikace-aikace ne tasiri mala'iku da nimesulide. Saboda haka, "Naiz" za kudin 120-145 rubles domin a tube na 20 g ko 215-275 rubles (50 g). Gel "nimulid" kadan mai rahusa: 115-150 rubles da tube girma na '30

A ƙarshe ina so in ce da wadannan. Yanke shawarar amfani "nimesulide", wani analogue ko wani NSAIDs kamata a dauka da halartar likita. Kawai kiwon lafiya masu sana'a za a iya yadda ya kamata tantance mai tsanani daga cikin kiwon lafiya na marasa lafiya, to la'akari duk related cuta, zabi miyagun ƙwayoyi sashi zuwa zaži kuma samar da wani magani da dabara domin rage girman da alama na illa da kuma samun mafi kyau da sakamakon.