Vitrification na oocytes: abin da yake da shi?

A cikin 'yan shekaru, a cikin vitro hadi da aka bunkasa sosai da sauri. Wannan hanya da aka daina dauke su wani abu m, kuma m ga talakawa mutane. IVF ne da za'ayi a ko'ina cikin duniya. Musamman dakunan gwaje-gwaje da kuma kananan dakunan shan magani suna samuwa a kowace babbar birni. Kowace shekara don inganta sabuwar, ingantattun hanyoyin haihuwa. Ta hanyar ci gaba da wannan hanyar, da yawa infertile ma'aurata su iya zama iyaye. Sau da yawa da tarin bayanai game da IVF, mata suna fuskantar wani lokaci kamar vitrification na oocytes. Wannan kalma tana nufin wani gwada sabon hanya da cewa ba ka damar inganta ingancin qwai.

A ra'ayi na "oocyte vitrification" - abin da yake da shi?

Don gane da yadda aiwatar da vitrification, dole ne ka yi wani tunani na a vitro hadi. Wannan hanya ya shafi daukan samfur na mace jam sel (oocytes) daga ovaries. To, akwai su tsarkakewa da kuma hadi maniyyi bayarwa ko abokin (idan mijin ba zai iya samun yara). Bayan wannan, da rabo zygote aka sanya a cikin igiyar ciki rami. Vitrification na oocytes - wata hanya mai kama da cryopreservation na oocytes. Duk da haka, shi ne mafi m. Karkashin vitrification nufi daskarewa m jam sel. A sakamakon haka, da oocytes za a iya adana na dogon lokaci. Duk da "daskararre" jiha, Vitrified Kwayoyin kasance mai yiwuwa. Wannan hanya da aka dauke su zama wata babbar nasara a magani, saboda godiya ga ta mata na iya samun wani jariri, ko da in babu haihuwa gabobin.

Abin da aka manufar oocyte vitrification ne da za'ayi?

A Turai, Concepts kamar cryopreservation, vitrification na tãyuna da oocytes, da aka sani na dogon lokaci. Wannan za a iya gani a kan yammacin fim a kan magani. A kasashe na tsohon Tarayyar Soviet, ma, likitoci saba da wadannan sharuddan shekaru da dama. Duk da haka, wadannan hanyoyin sun zama available ga marasa lafiya kwanan nan. A mafi yawan lokuta, vitrification na oocytes samar a vitro hadi. A lokacin da daskarewa da m Kwayoyin a cikin irin wannan hanya a mace yana da mafi damar nasara IVF. A rukunin farko na zaba oocytes daga kwai ba zai iya kwanta. A wannan sake-daukan samfur na kayan da aka ba da ake bukata, kamar yadda akwai riga Vitrified Kwayoyin. Bugu da kari, akwai lokuta a lõkacin da wata bakararre biyu tambaye ga adana oocytes na dogon lokaci. shi ne sau da yawa ake bukata a cikin daban-daban pathological yanayi a wanda wata mace ta iya ba da 'ya'ya. Har ila yau, tare da irin wannan fatawar miƙa marasa lafiya shirya domin tiyata don cire haihuwa gabobin.

A karkashin wani pathologies bayar da shawarar vitrification qwai?

Vitrification na oocytes da tãyuna - a biya hanya samuwa ga kowa da kowa. Special alamomi ga shi ba shi da, Duk da haka, shi wajibi ne kawai a cikin takamaiman lokuta. Wannan ba ya nufin cewa wasu mata ba zai iya iya vitrified su Kwayoyin. Duk da haka, a cikin rashi na dalilai domin daskarewa oocytes a irin wannan fashion ga marasa lafiya bayar da shawarar cryopreservation. Mafi sau da yawa vitrification aka gudanar a karkashin wadannan yanayi:

1. Shirya don ovariectomy. Wannan aiki ne da za'ayi a ovarian ciwon daji da kuma zargin da ta ci gaba. Wannan dalilin ne ba sosai tartsatsi, tun a mafi yawan lokuta, gynecological ciwon daji pathologies an cire kuma ya zauna cikin mahaifa.
2. Rashin iyawa samu maniyyi kullum ci na oocytes. Saboda wannan dalili, da Kwayoyin bukatar da za a daskarewa idan dai littattafai na hadi ba za a sanya.
3. Cancer da wani sarrafawa. Ko da kuwa inda shi yana da wani ciwon daji na bukatar radiotherapy da kuma lura da sinadaran (cytostatic) kwayoyi. Kowace daga cikin wadannan hanyoyin a ke so effects ciki. Bayan wadannan jiyya hallaka ba kawai da ciwon daji, amma kuma da lafiya Kwayoyin, ciki har da oocytes.
4. Mace ta marmarin da yara a wani m lokaci, misali, bayan menopause. A irin haka da wuya cryopreservation ne m saboda kwai misãlin tare da wannan Hanyar mai yiwuwa ga tsawo. Saboda haka, likitoci bayar da shawarar madadin Hanyar - vitrification na oocytes.
5. Maimaita IVF, idan karo na farko da kwai ba saba. A wannan yanayin, miƙa vitrification to ba yi da kayan sau uku.

Vitrified oocytes bayarwa - abin da yake da shi?

A wasu lokuta, a bakararre tururi ne iya yi ciki yaro, ko da taimako na a vitro hadi. Muna magana ne game da mata tare da mai illa aiki na gonads. A saboda wannan dalili, bankuna masu bada taimako oocytes aka ɓullo. Abin baƙin ciki, ba su da samuwa a duk ƙasashe. All m jam sel ne a vitrified jihar, sabõda haka sũ, za a iya adana. Alamomi ga IVF amfani da mai bayarwa oocytes ne:

1. Genetically m Pathology - ovarian gazawar ciwo.
2. Babu oocytes saboda da shekaru halaye na haihuwa tsarin (shekaru 40 da mazan).
3. Rashin iyawa ta da ovulation saboda m shisshigi a kan ovaries, jiyyar cutar sankara daukan hotuna.
4. A hadarin wani yaro da kwayoyin cutar.
5. Maimaita IVF, bai bada sakamakon a sakamakon "matalauta quality" na nasu qwai.

Wa zai iya zama mai bayarwa oocytes vitrified: Bukatun

Family Planning - wannan ne mai matukar tsanani yanke shawara, musamman a lokuta a lokacin da ma'aurata da aka tilasta yin amfani da bayarwa Kwayoyin. Kafin ka samu oocytes da kuma azabtar da su da vitrification, likita da za'ayi yawa safiyo na biyu da mace da kuma kayan bayar. Daya daga cikin yanayi kafa a cikin banki na daskararre ova, shi ne a sakaya sunansa. Wato, da iyaye ba su sani ba game da mai bayarwa, da kuma mataimakin versa. Bukatun mata da suka zabi su vitrified oocytes:

1. Age: 20-35 shekaru.
2. A rashin somatic da kwayoyin cututtuka.
3. Tãna tãshi da sauƙi furta phenotype.
4. A gaban mai bayarwa a kalla daya yaro na da nasu.
5. Amince da wa sirri.

Dabara na vitrification

Kafin ka fara zuwa daskare mace gametes, aka gudanar ovulation ruri. Wajibi ne cewa oocytes kasance da dama, maimakon daya. Bayan al'ada ripening faruwa a lokacin ovulation da follicle amfanin ƙasa na daya kawai ovum. Ruri da aka yi tare da magani. Next aka yi a pelvic duban dan tayi. Idan ka sami cewa ovulation an gane kuma oocytes a cikin kwai a isa yawa, da IVF hanya ake ci gaba. cell girbi ne da za'ayi a karkashin janar maganin sa barci. Don huda allura buga shi a can, inda oocytes, dukan hanya aka yi a karkashin duban dan tayi shiriya. Bayan shan kayan fara na gaba mataki - adana m oocytes. Vitrification na oocytes aka yi a cikin halitta sake zagayowar saboda da m daskarewa Hanyar. Wannan shi ne babban alama ce ta wannan tanadin Hanyar.

A abũbuwan amfãni daga vitrification na oocytes

Ganin cewa vitrikatsii aiwatar fara hankali maye gurbin sauran hanyoyin da adana ova da tãyuna, shi ne fin so ba kawai likitoci amma kuma ga marasa lafiya. Wannan hanya yana da wadannan abũbuwan amfãni:

1. The yiwuwar jinkirta ciki. Saboda gaskiya cewa oocytes da jinjirin suna daskarewa na dogon lokaci (dangane da hukuncin mace).
2. A ikon sake IVF hanya ba tare da shan littattafai na biyu (ko fiye) sau.
3. Da ikon yin ciki bayan tiyata a kan al'aura gland, radiation da jiyyar cutar sankara.

Menene bambanci tsakanin vitrification da cryopreservation qwai?

Kamar yadda aka sani, da matakai kriokenservatsii da vitrification na oocytes ne sosai kama. Duka hanyoyin da ake tsara don misãlin na oocytes da tãyuna domin ya kula da su viability. Duk da haka, akwai wasu bambance-bambance. Sau da yawa, m oocyte cryopreservation lalace. Wannan shi ne saboda a gaskiya wannan Hanyar ya shafi jinkirin daskarewa abu. A sakamakon haka, da ruwa cytoplasm tuba a cikin kankara lu'ulu'u ne. Dõmin sun lalata cell bango. An kyau kwarai Hanyar cryopreservation na oocytes ne vitrification. Kashi defrost lokacin dauke da fitar da yawa m, kamar yadda da sanyaya qwai auku kusan nan take. Wannan shi ne babban bambanci daga cryopreservation suna dauke sabon fasaha don kula da dogon oocytes a mai yiwuwa jihar. Don jinkirta ganewa na dogon lokaci iya kawai Hanyar vitrification. Cryopreservation ba samar da irin wannan jurewa.

Ta yaya ne IVF bayan vitrification na oocytes?

Oocyte vitrification ne da za'ayi a ko'ina. Daskarewa gametes da tãyuna na dogon lokaci tsunduma kawai a sosai na musamman dakunan gwaje-gwaje. Kusan kowace asibiti tare da wannan kayan aiki na banki na bayarwa oocytes vitrified. Da zarar wata mace ta yanke shawarar so juna biyu yaro, da Kwayoyin suna thawed. Sa'an nan amfani da ICSI dabara aka yi hadi. A sakamakon tayi ne hõre culturing (3-5 days) da kuma shukakkun cikin shirye endometrium. Sauran Kwayoyin za a iya hadu sake vitrified. Lokacin da wani ƙoƙari na implant IVF hanya an maimaita.

Vitrification na oocytes: reviews likitoci

A halin yanzu, vitrification da kuma ajiya na oocytes da jinjirin da aka yi a cikin dukkan manyan biranen ɓullo da magani. Da zarar wannan hanya da aka gwada da kuma ya tabbatar da kanta, likitoci magana game da shi gaskiya ma, Gamsuwa da abũbuwan amfãni a kan wasu (a baya) ajiya hanyoyin qwai. Iya zuwa daskare nasu oocytes su da yawa mata. A hanya Kudinsa 12 dubu rubles. Wannan farashin ne saboda vitrification. A kudin ajiya na daskararren kwayoyin halitta ne 1000 rubles da watan.