Antidiuretic hormone (Adh). Mugunya antidiuretic hormone

Vasopressin - antidiuretic hormone - samar da hypothalamus, wanda aka located a cikin na baya pituitary (neurohypophysis). Wannan hormone tabbatar homeostasis a cikin jikin mutum, rike ruwa balance. Saboda haka, misali, dehydration ko m zub da jini a ƙarƙashin rinjayar vasopressin hada da hanyoyin tabbatar da cewa lõkacin fatara daga ruwa hasãra. Saboda haka, antidiuretic hormone (Adh) kawai ba da damar mu mu bushe.

Ina Adh aka hada?

Antidiuretic hormone samar a cikin manyan cell neurons na supraoptic tsakiya na hypothalamus da ta ɗaure su neyrofizinom (m-gina jiki). Bugu da ari, shi directed zuwa ga raya lobe daga cikin hypophysis kuma akwai tara a hypothalamic neurons. Matsayin da ake bukata daga can shi shiga cikin jini. Adh mugunya aka shafi:

1. Jini (BP).
2. da jini osmolarity.
3. A girma daga jini kẽwayãwa a cikin jiki.

Halittu effects na anti-diuretic hormone

Lokacin da high jini mugunya na antidiuretic hormone suppressed kuma conversely, da fall a jini da 40% na al'ada vasopressin kira za a iya ƙara daga cikin saba kullum da ake bukata na 100 sau.

da jini osmolarity aka kai tsaye alaka da electrolyte abun da ke ciki na jini. Da zarar osmolarity na jini da dama a kasa m m matsayin, yana farawa da karin kasafi na vasopressin a cikin jini. Tare da karuwa a jini osmolality sama da halatta norms mutumin m. A amfani da manyan yawa na ruwa cike da hazo da hormone. Saboda haka, kariya ne da za'ayi ta dehydration.

Yadda antidiuretic hormone musababin da canji a cikin juz'i na zagawa da jini? Idan m jini da asarar musamman rabe located in hagu atrium da kuma kira volyumoretseptorami amsa ga wata karu a jini girma da kuma jini drop. Wannan alama ta shiga neurohypophysis da murmurewa vasopressin ƙaruwa. A hormone exerts mataki a kan jini da kuma su rabe Narrows da lumen. Wannan na taimaka wa lõkacin fatara daga zub da jini da kuma kara hana drop a jini.

Take hakki na kira da mugunya Adh

Wadannan cuta iya hade tare da wani kasa yawan vasopressin ko ta wuce haddi. Alal misali, da ciwon sukari insipidus akwai wani kasa matakin na Adh, yayin da ciwo Constantin ion Parhon ta overabundance.

ciwon sukari insipidus

A wannan cuta, koda reabsorption na ruwa rage-rage da cika fuska. Wannan za a iya yuwuwa ta biyu hali:

1. Da bai dace ba mugunya vasopressin - lõkacin da ta je ciwon sukari insipidus tsakiyar asalin.
2. Rage koda mayar da martani ga Adh - wannan ya faru a lokacin da wani neurogenic nau'i na ciwon sukari insipidus.

Marasa lafiya fama da wannan Pathology kullum diuresis iya isa 20 lita. Fitsari yayin da low-natsuwa. Marasa lafiya ne kullum m, kuma sun sha da yawa m. Don gano abin da irin wani nau'i na ciwon sukari insipidus haƙuri shan wahala, yi amfani da wani analogue da hormone vasopressin - wani magani "Desmopressin". A warkewa sakamako daga cikin miyagun ƙwayoyi aka nuna ne kawai a tsakiyar nau'i na cutar.

ciwo na bai dace ba antidiuretic hormone mugunya

Haka kuma an kira ciwo na bai dace ba mugunya Adh. Cutar da ake raka ta wuce kima mugunya vasopressin, yayin da a can ne a rage osmotic matsa lamba na jini jini. Kamar wancan akwai da wadannan cututtuka:

• Muscle twitching kuma cramps.
• Tashin zuciya, rashin ci, zai yiwu amai.
• Zai yiwu lethargy, coma.

Haƙuri yanayin tabarbarewa.Idan lokacin da jiki ruwa (intravenously ko a cikin wani abin sha). Lokacin da tsanani ƙuntatawa na ruwa ci kuma sokewa igiyar jini jiko a marasa lafiya cikin gafarta musu.

Abin da cututtuka nuna wani kasa matakin na vasopressin?

Idan antidiuretic hormone da aka hada a takaice wadata, mutane na iya fuskanci:

• Very m.
• M urination.
• Rashin ruwa da fata, wanda aka kullum ci gaba.
• Rashin ci.
• Matsaloli tare da gastrointestinal fili (gastritis, colitis, maƙarƙashiya).
• Matsaloli tare da jima'i Sphere. The maza - rage iko a mata - hailar cuta.
• Kullum gajiya.
• Karuwan intracranial matsa lamba.
• Rage hangen nesa.

Kamar yadda aka nuna ta rage na Adh?

Raguwa a jini vasopressin iya faruwa a cikin wadannan yanayi:

• Jamhuriyar ciwon sukari insipidus.
• Nephrotic ciwo.
• Psychogenic polydipsia.

Mene ne bayyanar cututtuka Point to ya karu mugunya Adh?

• Rage kullum diuresis (fitsari samarwa).
• Weight riba a rage ci.
• Lethargy da juwa.
• Ciwon kai.
• Tashin zuciya da kuma amai.
• Muscle cramps.
• Daban-daban raunuka na juyayi tsarin.
• barci disturbances.

A karkashin abin da yanayi da ya lura karuwa a matakin na Adh?

A karuwa na vasopressin iya lura a pathologies halin da ya wuce kima mugunya na hormone, da suka hada da:

• Julien-Barre ciwo.
• Intermittent m porphyria.

Bugu da kari, shi ne zai yiwu a karkashin wadannan yanayi:

• kwakwalwa ƙari (primary ko metastases).
• Cututtuka na kwakwalwa.
• Jijiyoyin bugun gini cututtuka na kwakwalwa.
• Tuberculous meningitis.
• Ciwon huhu.

Antidiuretic hormone - inda sallama?

Daya daga cikin mafi inganci hanyoyin domin tabbatar da dalilin da Adh a cikin jini ne a radioimmunoassay (RIA). Layi daya domin sanin osmolarity na jini jini. A analysis za a iya yi a cikin wani endocrinology cibiyar. Mutane da yawa masu zaman kansu shan magani kuma yi irin wannan ƙididdiga. Jini aikata daga jijiyar cikin shambura ba tare da wani preservatives.

Kafin bayarwa na jini ga antidiuretic hormone ya zama 10-12 hour hutu a cikin abinci. Jiki da hankulansu danniya a kan Hauwa'u na da jini kyauta iya karkatar da bincike. Wannan yana nufin cewa rana kafin isar da bincike shi ne bu mai kyau kada su shiga a cikin m jiki aiki, ba su shiga a wasanni gasa, ba su yi jarrabawa, da dai sauransu

Kwayoyi da zai iya ƙara matakin na Adh, ya kamata a soke. Idan wannan shi ne ba zai yiwu ga wani dalili, da bukatar siffofin wajibi ne don saka abin da miyagun ƙwayoyi da aka yi amfani da, a lõkacin da kuma a cikin abin da kashi. Murguda hakikanin matakin na Adh iya da wadannan kwayoyi:

• estrogens.
• kwayoyin maganin barci.
• anesthetics.
• tranquilizers.
• "Morphine".
• "Oxytocin".
• "Cyclophosphamide".
• "Carbamazepine".
• "Vincristine".
• "Hlorpropamid".
• "Chlorothiazide".
• "Lithium carbonate".

Analysis na antidiuretic hormone za a iya dauka ba a baya fiye da mako guda bayan da radioisotope ko radiological bincike.

Wannan binciken ya yale mu mu bambance nephrogenic ciwon sukari insipidus da pituitary ciwon sukari insipidus da syndromes halin da ya wuce kima mugunya Adh.