Beta-blockers: kwayoyi jerin, alamomi ga yin amfani da

Kwayoyi da gagarumin warkewa effects suna yadu amfani da kwararru. Suna amfani domin lura da cardiac cututtuka, wanda su ne mafi m tsakanin sauran pathologies. Wadannan cututtuka su ne mafi kusantar su kai ga mutuwa da marasa lafiya. Magunguna da ake bukata don bi da wadannan cututtuka, suna beta-blockers. List aji na kwayoyi, kunsha na 4 sassan, kuma su rarrabuwa aka gabatar a kasa.

Nau'in beta-blockers

A sunadarai tsarin da miyagun ƙwayoyi aji ba uniform kuma daga asibiti effects ne m. Fiye da muhimmanci ware musamman don wani musamman tsoka mai amsa sigina da kuma dangantaka a gare shi. A mafi girma da bayani dalla-dalla ga beta-1 rabe, da m gefen sakamakon kwayoyi. A wannan batun, jerin beta-shafi kwayoyi gabatar a matsayin tunanin mutuntaka.

A ƙarni na farko na kayayyakin:

• ba zabe beta-tsoka mai amsa sigina 1 da kuma irin 2, "Propranolol" da "Sotalol", "timolol" da "oxprenolol", "nadolol," "Penbutamol".

The biyu ƙarni:

• zabe beta tsoka mai amsa sigina irin 1, "bisoprolol" da "Metoprolol", "acebutolol" da "Atenolol", "Esmolol."

Tsara ta uku:

• Zababben beta 1 blockers tare da ƙarin pharmacological Properties: "Nebivolol" da "Betaksalol", "talinolol" da "celiprolol".
• Nelektivnye beta-1 da kuma beta-2 blockers tare da ƙarin pharmacological Properties: "Carvedilol" da "carteolol," "Labetalol" da "bucindolol".

Wadannan beta-blockers (ganin jerin kwayoyi. Sama) a daban-daban sau kasance da babban rukuni na kwayoyi da cewa an yi amfani da da kuma yanzu amfani da cututtuka na jini da kuma zuciya. Mutane da yawa daga gare su, mafi yawa wakilan da na biyu da kuma na uku a zamaninsu, ana amfani da shi yau. Saboda su pharmacological effects sarrafa don sarrafa zuciya kudi da kuma rike ectopic kari ga ventricles, don rage mita na angina harin na angina.

Key to rarrabuwa

A farkon kwayoyi su ne 'yan ƙarni na farko, wato, ba zabe beta-blockers. A jerin kwayoyi da kuma shirye-shirye da aka ba a sama. Wadannan kwayoyi iya tarewa da rabe na 1st da 2nd irin, samar da duka biyu warkewa illa da kuma gefen, wanda aka bayyana bronchospasm. Saboda ana contraindicated a marasa lafiya tare da COPD, Bronchial asma. A mafi muhimmanci na farko tsara kwayoyi ne "Propranolol", "Sotalol", "timolol".

Daga cikin wakilan biyu ƙarni na jerin kwayoyi beta-blockers, ginshikai na mataki na wanda ake dangantawa da wata primary tarewa na farko da irin rabe. Suna halin mai rauni dangantaka domin tsoka mai amsa sigina irin 2, saboda da wuya sa bronchospasm a marasa lafiya tare da fuka da kuma COPD. A mafi muhimmanci shirye-shirye na da 2nd tsara su ne "bisoprolol" da "Metoprolol", "Atenolol".

A tsara ta uku da beta-blockers

Wakilai na tsara ta uku - shi ne latest beta blockers. A jerin kwayoyi hada da "Nebivolol", "carvedilol", "Labetalol", "bucindolol", "celiprolol" da sauransu (ga. Sama). A mafi muhimmanci daga wani asibiti ra'ayi suna da wadannan: "Nebivolol" da "Carvedilol". Origin advantageously katange beta-1 rabe da kuma stimulates a saki NO. Wannan ne ya sa ta fa] a] jini da kuma rage hadarin atherosclerotic plaques.

An yi imani da cewa beta-blockers - kwayoyi don hauhawar jini da kuma ciwon zuciya, yayin da "Nebivolol" - a Generic miyagun ƙwayoyi da cewa shi ne ma dace domin duka biyu dalilai. Duk da haka, da kudin ne dan kadan fi farashin da sauransu. Similar a Properties amma dan kadan ya fi tsada, shi ne "Carvedilol". Yana hadawa da kaddarorin da beta-1 da kuma alpha-shafi cewa taimaka wajen rage da mita da kuma karfi na zuciya contractions, kazalika da fa] a] periphery daga cikin tasoshin.

Wadannan effects ba ka damar sarrafa kullum zuciya maye da hauhawar jini. Kuma a cikin hali na zuciya rashin cin nasara, "Carvedilol" - da miyagun ƙwayoyi da zabi, domin har yanzu shi ne wani antioxidant. Saboda kayan aiki hana ƙarin tsanani daga atherosclerotic plaques.

Alamomi miyagun ƙwayoyi kungiyar

All alamomi ga yin amfani da beta-blockers dogara ne a kan takamaiman Properties na musamman magani kungiyar. A ba zabe blockers alamomi ne narrower, alhãli kuwa zabe mafi aminci kuma za a iya amfani da more yadu. A general, da alamomi ne na kowa, ko da yake suna iyakance ta da rashin yiwuwar da amfani da kwayoyi a wasu marasa lafiya. Ga wadanda ba zabe kwayoyi wadannan alamomi:

• tsokar zuciya infarction a duk lokaci, angina, sauran, m angina .
• Atrial fibrillation normoforma da tahiforma.
• sinus tachyarrhythmia tare da dauke a tare da ko ba tare da shi ventricles.
• zuciya rashin cin nasara (na kullum).
• hauhawar jini .
• hyperthyroidism, hyperthyroidism, tare da ko ba tare da wani rikicin na shi.
• pheochromocytoma daga wani rikicin na asali far ko cuta preoperatively.
• migraine.
• Dissecting aortic aneurysm.
• miyagun ƙwayoyi, ko barasa karbo ciwo.

Saboda da tsaro na da yawa kungiyoyin na kwayoyi, musamman na biyu da kuma na uku tsara, jerin kwayoyi beta-blockers, sau da yawa bayyana a cikin records na lura da zuciya da kuma jijiyoyin bugun gini cututtuka. Bisa ga mita na aikace-aikace, su ne kusan m da ACE hanawa, wanda aka yi amfani da magani na zuciya da kuma gazawar hauhawar jini da rayuwa ciwo da kuma ba tare da shi. Tare da diuretics, wadannan kungiyoyin biyu da kwayoyi iya kara tsawon rayuwar a kullum cardiac gazawar.

contraindications

Beta-blockers, kazalika da sauran kwayoyi, da wasu contraindications. Kuma saboda kwayoyi aiki a kan rabe, su ne mafi aminci fiye da ACE hanawa. Janar contraindications:

• asma, COPD.
• bradyarrhythmia, marasa lafiya sinus ciwo.
• atrioventricular block II digiri.
• symptomatic hypotension.
• ciki, yaro.
• decompensated zuciya rashin cin nasara - zuciya rashin cin nasara II B-III.

Har ila yau, abubuwa a matsayin Contra rashin lafiyan dauki a mayar da martani ga mai karɓa shafi. Idan wani magani alerji tasowa, da maye magani zuwa wani solves matsalar.

Gurbin na asibiti amfani da kwayoyi

Lokacin da angina kwayoyi rage mita na angina harin da su ƙarfi, rage da alama na m jijiyoyin zuciya events. A CHF jiyya ba tare da beta-blockers da ACE hanawa da diuretics biyu ƙaruwa rayuwar jama'a. Magunguna ne tasiri a cikin iko tachyarrhythmias kuma zalunta m ectopic lashe a ventricle. A cikin duka, kudi don taimaka sarrafa alamun cutar zuciya.

Karshe game da beta-blockers

"Carvedilol" da "Nebivolol" - shi ne mafi kyau beta-blockers. A jerin kwayoyi da cewa ya nuna fifikon aiki na beta-rabe, complements jerin babban therapeutically muhimmanci kwayoyi. Saboda a asibiti yi da ya kamata a yi amfani da ko dai ta hanyar tsara ta uku, wato "Carvedilol" ko "Nebivolol" ko yawanci zabe domin beta-1 tsoka mai amsa sigina kwayoyi, "bisoprolol", "metoprolol". Ko a yau, da aikace-aikace ba ka damar sarrafa hauhawar jini da kuma mu bi da cutar zuciya.