Jima'i chromatin

Sau da yawa a cikin yara gynecology da andrology akwai bukatar gudanar da kwayoyin jarrabawa na haƙuri. Wannan hanya damar mafi m kafa dalilin cutar ta taso, to karba dole magani da kuma ƙayyade forecast a cikin ci gaban da cutar.

Sex chromatin - wani muhimmin nuna alama na al'ada jima'i ci gaba a salon salula matakin. Ya ganewar asali yana da muhimmanci a lokuta idan ta je anomalies a cikin tsarin da waje genitalia. A binciken da aka gudanar a matsayin ganewa na cututtuka da chromosomal munanan a gaban illa jima'i ci gaba. A dalilin wannan zai iya zama a matsayin babu haila a 'yan mata da kuma hypoplasia na ovaries ko rage aiki a boys.

Sex chromatin aka fara gano masana Yahaya. Bar a shekarar 1949. Gudanar da bincike na jijiya Kwayoyin Cats, ya jawabin a kan periphery na tsakiya chromatin samuwar. Daga bisani, wannan muhimmanci alama na mace somatic Kwayoyin aka gano a mafiya yawa daga cikin wakilan da oda na dabbobi masu shayarwa. Namiji Kwayoyin irin corpuscles aka iske ba. Barr jiki ne bangaren da dukan jiki Kwayoyin na mata. Kuma a wasu lokuta yana da wani irin appendages ( "drumsticks"). Somatic cell - na game sassa na jikin mutum. Wadannan sun hada da duk jiki Kwayoyin fãce gametes. Wannan samu a yarda ya fadada da ra'ayin daga cikin hanyoyin da na jima'i kafiya a cikin mutane da kuma dabbobi masu shayarwa.

A gaban mace jiki Barr jikinsu saboda gaban somatic Kwayoyin a cikin biyu X chromosomes. Haka kuma aiki yana daya kawai daga cikinsu. Wannan shi ne dalilin da ya sa a cikin mata Kwayoyin, akwai ko da yaushe wani Barr jiki. Wannan ka'idar da aka kara yarda gane anomalies a ci gaba da kwayoyin. Alal misali, a cell da uku chromosomes zai yi biyu maraƙi, tare da hudu - uku, da dai sauransu Ganewar asali mahaukaci cell ci gaban da za a iya amfani da mata da maza. Tun 1953, wannan samu an yi amfani da baje domin sanin ainihin yawan X chromosomes a mutane da raya ci gaban nakasa.

Jima'i chromatin ko Barr jiki, tare da duhu taro yayi kama da taso, triangular ko sanda-dimbin yawa, wanda aka located kusa da ciki surface na nukiliya membrane. Wannan m X-chromosome, wanda ta hanyar da diamita ne kasa da 1 micron. Ganewa na Barr jikuna a sel 10-12% na binciken ya nuna wani tabbatacce jima'i chromatin. Binciken abu yawanci hidima da epithelium na buccal mucosa (ciki surface), farji, gashi follicles da ruwar. Idan adadi bai wuce kashi 5%, shi nuna wani mummunan jima'i chromatin.

Sex chromatin sa bambance-bambance a Interphase nuclei a maza da mata. An hade tare da siffofin aiki al'aura tsarin da su tsari. Barr jiki ne daga iri biyu: Y da kuma X. A farko embodiment ne a tsarin bangaren na Y-chromosome da aka gano mafi yawa a maza. Domin wadannan dalilai fluorochrome amfani riskar hasken ultraviolet. X-chromatin (Barr jiki) - an inactivated X chromosome. Its deactivation auku a farkon makonni na fetal ci gaba da kuma aka adana a mitosis na dogon lokaci.

Ya kamata a lura da cewa jima'i chromatin - shi ne mai tsauri tsarin. Yana iya bambanta dangane da sauran yanayin jiki da kuma metabolism na sel. Yana da wannan dalilin, da za su gudanar da wani binciken da aka ba da shawarar a lokacin da yin amfani da hormonal shirye-shirye, a cikin farkon kwanaki bayan haihuwa, bayan shan maganin rigakafi da sauran kwayoyi.

Yau, gaban jima'i chromatin likitoci ƙayyade da kwayoyin jima'i na yaro, kamu da daban-daban na asibiti siffofin gonadal dysgenesis da hermaphroditism. Kima domin ganewa na bangaren yadu a yi amfani na bincike yi.