"Celecoxib": umarnin don amfani, reviews. miyagun ƙwayoyi analogues

Jiyya cututtuka dangantawa da lalacewar da musculoskeletal tsarin, bukatu, daga pharmaceutical kasuwar haifar da sabon kwayoyi tare da m illa da wadata ba. Masana kimiyya sun gano da kuma hada wani sabon ƙarni na ba-steroidal anti-kumburi kwayoyi a kan tushen da celecoxib. Wadannan kwayoyi sun rage yawan guba da kuma mafi jure ta cikin jiki.

Description of "Celecoxib" miyagun ƙwayoyi

Abu celecoxib yana da wani kodadde rawaya launi da kuma nufin da kungiyar coxibs wanda ya nuna zabe hanawa na cyclooxygenase biyu type. Medicaments dangane da mahadi na yanzu mallaka furta anti-mai kumburi da analgesic Properties. The asali miyagun ƙwayoyi a kan tushen da celecoxib yana dauke da za a ci gaba da American kamfanin "Pfizer" miyagun ƙwayoyi "Celebrex". shi ya yi karatu da kuma bincika pharmacodynamic halaye na yawan guba ga jikin mutum.

A wasu medicaments dauke da aiki abu celecoxib ne Generic, ciki har da miyagun ƙwayoyi "celecoxib".

sashi siffofin

Samuwa miyagun ƙwayoyi a wuya gelatin capsules a sashi na aiki sashi, 100 MG da 200 MG. Ba kamar sauran wadanda ba steroid anti-kumburi jamiái, yana da wani sashi tsari a matsayin wani maganin shafawa, gel, injectable mafita ko suspensions. Tare da wasu marasa lafiya kuskure kira saki form "Celecoxib" miyagun ƙwayoyi - Allunan, ko da yake muna magana ne game da capsules.

tsarin

The aiki sashi ne celecoxib abu a wani adadin na 100 MG da 200 MG. A abun da ke ciki na capsules hada da karin aka gyara da samar da sarari cika, da flowability da kwanciyar hankali na granulated cakuda. Wadannan sun hada da lactose, sodium lauryl sulfate, polyvinylpyrrolidone (K30), sodium croscarmellose, magnesium stearate.

A haɗe zuwa da miyagun ƙwayoyi "celecoxib" umurci manual qunshi da abun da ke ciki da kuma halayyar bayyanar wani gelatin kwantena harsashi. Bisa ga bayanin, shi ya dubi maras ban sha'awa, da kusan fararen a launi da kuma alama da ãyõyi "100" ko "200", located a kan blue ko rawaya band, bi da bi. Wannan damar rarrabe capsules da daban-daban dosages. Abun da ke ciki na rawaya da blue inks ma fentin daki-daki, na nuna dyes m to kwayoyin.

kama da kwayoyi

Magani samfurin "Celecoxib", analogues na wanda kuma ya ƙunshi aiki abu celecoxib, za a iya nuna wannan warkewa sakamako a kan osteoarthritis na mutum kwarangwal.

The asali miyagun ƙwayoyi "Celebrex" da kuma ta Generic "Celecoxib", "Artoksib", "Zitsel", "Revmoksib", "Ranseleks" suna dauke m magunguna. Duk da haka, asalin farashin category za kudin wani tsari na girma fi tsada fiye da takwarorinsu.

A shirye-shiryen "Celebrex" ya ƙunshi celecoxib a sashi na 100 da kuma 200 MG matsayin medicament "celecoxib". Karin aka gyara daga cikin kwantena da kuma ta ambulan na iya bambanta duka biyu a ingantaccen da kuma gwada yawa abun da ke ciki da cewa ba ya shafar dũkiyõyinsu. Game da tsari na saki na Generic "Celecoxib" miyagun ƙwayoyi analogues ake samar kawai a wuya gelatin capsules for ciki amfani.

Akwai wadanda ba steroidal anti-kumburi jamiái, cyclooxygenase daidai zartar da na biyu da irin amma da ciwon da bambance-bambance a cikin abun da ke ciki na aiki bangaren, da pharmacokinetic da pharmacodynamic halaye. Wadannan sun hada da sulfonamide fili nimesulide wanda a kullum sashi na 200 MG yadda ya kamata ya bi da cututtuka na osteoarthritis da kuma rheumatoid amosanin gabbai. Formulations dangane da anti-mai kumburi da analgesic sakamako da inhibiting da cyclooxygenase biyu da kuma wani karami har - na farko irin, shafi wani iri-iri masu shiga tsakani na zafi da kumburi.

Kamar yadda nimesulide, celecoxib ne wakilin sulfonamide aji na abubuwa, da kuma a cikin wani kullum sashi na 200 MG gusar bayyanar cututtuka na osteoarthritis. Yana ba hana cyclooxygenase farko da irin da ayyukan a kan wani karamin yawan masu shiga tsakani na zafi da kumburi.

An madadin jiyya coxibs baka gwamnati ne injectable siffofin NSAIDs. Daya daga cikin manyan abũbuwan amfãni daga "Celecoxib" samfurin - Farashin. Injections (ampoules ga allura) da sauran wadanda ba steroidal anti-kumburi kwayoyi kudin mafi tsada, amma irin wannan allura yadda ya dace shi ne mafi m ga sakamakon daga yin amfani da kwayoyi a cikin m siffofin.

inji na mataki

Drug "Celecoxib" - wani magani da cewa wakiltar wani sabon ƙarni na nonsteroidal anti-kumburi jamiái, anti-kumburi, analgesic, antipyretic aiki. Its inji na mataki da ake dangantawa da tarewa da samuwar mai kumburi prostaglandins ta rage na ayyuka na Cox-2.

Kumburi halayen fararwa da shigar da na cyclooxygenase biyu type, bi da bi accelerates jari na prostaglandin kira da kuma abubuwa da bunkasa kumburi. Jihar tasowa kumburi da kuma zafi.

Cyclooxygenase farko da irin ba zai tasiri a warkewa kashi "celecoxib" shirye-shiryen. Umurnai na amfani bayyana inertia da miyagun ƙwayoyi game da wannan enzyme hade da ayyukan na physiological matakai abin da ke faruwa a cikin sel da gastrointestinal fili da kuma platelet Tsarin.

Har ila yau, a cikin umarnin da aka ba da bayanai a kan tasiri na kwayoyi a kan kodan. A karkashin mataki na celecoxib ne kasa da aka nuna a fitsari abun da ke ciki prostaglandin E2 da F1 na 6-keto-prostaglandin, amma ba ya canja kasafi na B2 11-dehydro-thromboxane, wanda ya nuna da zabe sakamako magani.

Amfani da miyagun ƙwayoyi "Celecoxib" ba ya haifar da wani karu a tacewa kudi a koda glomeruli tsofaffi da kuma a cikin marasa lafiya da na koda insufficiency.

Alamomi ga yin amfani da

A cewar pharmacodynamic halaye na cikin shirye-shiryen "celecoxib" aikace-aikace zai zama da karfi domin lura da rheumatoid da psoriatic amosanin gabbai, na kullum kumburi da zafi na kashin baya da kuma sacroiliac gidajen abinci da kuma osteoarthritis.

Saboda da analgesic Properties amfani ga m yanayin a musculoskeletal zafi bayan da m magani, dysmenorrhea, wanda yana tare da m haila. A anti-mai kumburi sakamako daga cikin miyagun ƙwayoyi ne da nufin rage outgrowths da polyps a cikin ciwon da kuma dubura a cikin ganewar asali "adenomatous polyposis".

Yadda za a yi

Dauki magani "Celecoxib" umarnin don amfani a ciki ya bayar da shawarar ba a haɗa tare da amfani da abinci. A capsules kada ka bude, kuma ba chewed, kuma ya yi lõma da dukan hanyar shan yalwa na ruwa.

Matsakaicin adadin celecoxib, wanda za a iya dauka a kowace rana shi ne 0.4 g Wannan shiri da ake amfani da kima ne kawai a rare lokuta.

Zuciya da jijiyoyin jini rikitarwa zai iya sa high allurai da kuma shafe tsawon magani da miyagun ƙwayoyi "Celecoxib". Guide ƙunshi bayani a kan kananan dosages ga symptomatic magani daga kowane karatu. Ya bada shawarwari a kan short amfani.

Don kawar da cututtuka dangantawa da osteoarthritis, da kuma ankylosing spondylitis, kullum dauki daya ko biyu sau da 200 MG na da miyagun ƙwayoyi.

Don kawar da cututtuka na rheumatoid amosanin gabbai ta amfani da kullum kashi na 200, ko 400 MG, wanda aka dauka a matsayin sau biyu.

Zafi da primary dysmenorrhea da aka bi a rana ta farko da babban kashi na 400 MG, tare da yiwu liyafar na kara 200 MG, da rana ta amfani da 200 MG sau 2 a rana.

The tsofaffi, da kuma marasa lafiya da ciwon m mataki kasa hanta ko m zuwa matsakaici koda insufficiency, babu recalculation na kashi ne da za'ayi.

Low nauyi (kasa da 50 kg), da talakawan tsanani daga hanta gazawar - data Categories ga marasa lafiya bi da tare da low allurai wajabta magani.

Yawanci, domin lura da kumburi tafiyar matakai a gidajen abinci amfani da magani tsarin dogara ne a kan yin amfani da dama da kwayoyi a cikin daban-daban sashi siffofin. Hada "celecoxib" kwantena, maganin shafawa, ko gel-type Warming "Apizatrona" ko "finalgon. Topical amfani Yanã da wani sakamako na wucin gadi, don haka aka yi amfani da tare da kwayoyi domin na cikin gida liyafar.

Wannan haramta yin amfani da

Ba dukan marasa lafiya da cututtuka na gidajen abinci, za ka iya yi da miyagun ƙwayoyi "Celecoxib". Umurnai na amfani ƙunshi jerin cututtuka da kuma yanayin a cikin abin da kayan aiki zai fi cutar da fiye da kyau. Wadannan sun hada da:

• amya, asma, rashin lafiyan yanayin da mataki na asfirin da kuma sauran nonsteroidal anti-kumburi kwayoyi.
• dawo da aiki dangantawa da jijiyoyin zuciya jijiya kewaye grafting .
• exacerbation na peptic miki.
• ciki da kuma na hanji na jini.
• kumburi daga cikin mucosa a cikin hanjinsu.
• zuciya rashin cin nasara.
• ischemic cututtuka na zuciya tsoka.
• asarar gefe arteries da cerebral tasoshin da illa cerebral jini ya kwarara.
• hanta nedostatochnosttyazheloy siffar.
• tsanani na koda gazawar.
• haihuwa;
• shayarwar da jariri.
• kasa da shekaru goma sha takwas da shekaru.
• hypersensitivity zuwa excipients.
• ya karu laulayi da sulfonamide bangaren.

Tare da hankali da yin amfani da miyagun ƙwayoyi "Celecoxib" ya zama mutane da cututtuka na gastrointestinal fili dangantawa da peptic miki zub da jini a baya, kamuwa da cuta daga cikin mucous kwayoyin na HALITTAR Helicobacter pylori.

ruwa riƙewa a cikin jiki da kuma taushi tsokoki edema, cuta na hanta sakandare mataki, zuciya da kuma jijiyoyin bugun gini cututtuka, a cikin jiki, cikinsa da karuwa a cikin cholesterol matakin a cikin jini jini lura sia metabolism, da ciwon sukari, sugar, somatic cututtuka a mai tsanani, kuma suna da wani dalilin matsakaicin m amfani da miyagun ƙwayoyi "celecoxib" karkashin kulawa na likita.

illa

Duk da m nasarori a cikin halittar wani sabon ƙarni na coxibs, wadannan abubuwa da kuma kwayoyi bisa su ba bã tãre da illa.

Rakiyar da miyagun ƙwayoyi "Celecoxib" umarnin don amfani, haƙuri shedu da kuma kwararru - da wadannan kafofin dauke da bayani game da yiwu illa su iya faruwa a cikin muhimmanci gabobin.

The yiwu mummunan tasiri a kan narkewa kamar tsarin halin da NSAID-gastropathy, zafi a ciki, tashin zuciya da amai, ƙwannafi, rage bukatar abinci ci da zawo. Dogon lokacin da yin amfani da high allurai zai iya sa ulceration da kuma zub da jini a cikin mucous membrane na ciki da kuma hanjinsu, zub da jini gumis, wuce kima kunnawa da transferase hanta.

M cuta an bayyana tashin hankali, da ciwon kai, dizziness, somnolence, rashin barci, depressive jihohi.

Tasiri a zuciya da jijiyoyin jini tsarin saboda ya karu matsa lamba a cikin jijiyoyi, da kuma tachycardia.

Shiri "celecoxib" rage jure cututtuka na numfashi tsarin, wanda za a iya bayyana a cikin ci gaban da sinusitis, rhinitis, pharyngitis, zafi a cikin hanci da makogwaro, tari, dyspnea, bronchospasm.

A tasiri daga cikin miyagun ƙwayoyi a kan hankula sa wani raguwa a auditory ji da kuma bayyanar tinnitus.

A cikin urinary tsarin rinjayar miyagun ƙwayoyi "Celecoxib" dõmin ka sami koda gazawar da ci gaban edema ciwo.

Game da jini-forming gabobin, da miyagun ƙwayoyi zai iya sa bayyanuwar agranulocytosis, anemia, leucopenia, thrombocytopenia.

Skin rashes iya faruwa tare da bayyanar rashin lafiyan pruritus, urticaria, photosensitivity, angioedema a fuska yankin, extremities, genitalia.

Features liyafar

Drug "Celecoxib" muhimmi hasara hade da wani ƙãra hadarin illa a kan zuciya da jijiyoyin jini tsarin manyan zuwa thrombosis, infarction na tsokar mai ban mamaki da tsoka da kuma bugun jini. Musamman ma hadarin ƙãra a lokacin kullum gwamnati na magani da marasa lafiya wanda akwai zuciya da jijiyoyin jini cututtuka.

Don rage hadarin irin wannan rikitarwa a marasa lafiya shan miyagun ƙwayoyi "Celecoxib" rubũta mafi ƙasƙanci kashi a mafi gajeren lokaci da magani. A haƙuri kamata tattauna tare da likita da zai yiwu ãyõyin cuta da kuma samun shawara a kan yadda za a amsa a lokacin da suke faruwa.

amfani da haɗin acetylsalicylic acid a cikin kadan allurai miyagun kwayoyi "celecoxib" Don rage zuciya da jijiyoyin jini cututtuka. Reviews na likitoci nuna antiplatelet sakamako na asfirin don bakin ciki da jini a lokacin da shan coxibs, wanda ba su da irin anti-thrombotic Properties. Yawanci, irin mai hade da aka nuna a tsofaffi da marasa lafiya da cuta da musculoskeletal tsarin da zuciya da jijiyoyin jini tsarin, gastrointestinal yawan guba ne ta ƙara a lokacin da ba zabe ba-steroidal anti-kumburi kwayoyi. Amma yin amfani da wani abu celecoxib tare da sauran NSAIDs ba da shawarar.

Ga marasa lafiya fama da cutar hawan jini, da ci gaba da kula da wannan siga lokacin samun "Celecoxib" miyagun ƙwayoyi.

Musamman hankali ya kamata a bai wa idanu da yanayin da kwayoyin a hade tare da anticoagulant (warfarin) da kuma antiplatelet abubuwa (acetylsalicylic acid, clopidogrel) ta amfani da mai zabe mai hanawa (citalopram, sertraline), inhibiting serotonin reuptake hanawa na CYP2C9 isozyme, kwamfutar hannu da siffofin glucocorticosteroids.

Da miyagun ƙwayoyi "celecoxib" inganta samar da prostaglandin abubuwa, wanda retard da ruwa a cikin jiki da kuma karfafa edema. Musamman da hankali a lura da wadannan kwayoyi bukatar zama mutanen da suke fama daga zuciya tsoka gazawar da kuma hawan jini. ya kamata a daina shan "Celecoxib" miyagun ƙwayoyi idan akwai alamun kumburi daga kyallen takarda.

Marasa lafiya da koda cuta magani coxibs kamata a tare da m dubawa na key Manuniya.

Lokacin da dehydration shan miyagun ƙwayoyi mai yiwuwa ne kawai bayan da rehydration Hakika rehydration.

Yanayin aiki "celecoxib" antipyretic miyagun ƙwayoyi saboda mataki kaiwa zuwa wahala da bincike index, kamar yadda dagagge zafin jiki a lokacin da ci gaban dauke da kwayar cutar yanayi.

A mataki na miyagun ƙwayoyi iya haifar da munanan a hanta aiki, musamman a cikin mutane tare da pre-data kasance cuta na hanta. Mai tsanani bayyanar cututtuka dangantawa da fulminant hepatitis, hanta nekrozomtkaney. Irin wannan yanayi faruwa nan da nan, amma kawai bayan kwana 30 bayan aikace-aikace "celecoxib" shirye-shiryen. Sa'an nan kuma ka so ka saka idanu yi a lura da hanta da wannan makaman, da kuma a yanayin da nauyi kashi ya kamata ka da sauri soke nadin.

Reviews domin lura da "Celecoxib"

Nonsteroidal anti-kumburi kwayoyi da aka kwashe kawai a kan takardar sayen magani. A sakamakon yin amfani da "Celecoxib" miyagun ƙwayoyi da sake dubawa na ta aikin ne gauraye. Daya magani taimaka wajen jimre da kumburi tafiyar matakai a cikin gidajen abinci, ga wasu shi ne m, kuma Yanã da wani yawan m events.

Kamar yadda mafi marasa lafiya kimanta da miyagun ƙwayoyi "Celecoxib"? Reviews nuna wani yawan matsalolin: jin zafi a ciki, koda, hailar cuta. Irin wannan marasa lafiya likita gudanar da sokewa medicament da kuma sanya madadin magani.

Bisa ga ra'ayin da na marasa lafiya a kan sakamakon kwayoyi a kan inflamed gidajen abinci, shi za a iya ƙarasa da cewa shi ne tasiri a yaki da amosanin gabbai. Don kawar da zafi bayyanar cututtuka, kumburi daga kyallen takarda a shafa yankin na wani kullum yanayi, marasa lafiya ne a cikin kaka da spring kudi na miyagun ƙwayoyi far "Celecoxib". Ana amfani da 'yan wasa a rauni da kuma gidajen abinci.

Musamman medicament abubuwa yadda ya kamata a hade tare da jin wuta man shafawa da mala'iku domin Topical aikace-aikace. Duk da haka, bisa ga shawarwari na dauke a cikin umarnin don amfani ba NSAID amfani da gajeren Darussan, domin kauce wa danniya a kan kodan, hanta, zuciya da kuma ciki. In ba haka ba ba za a kauce wa kasawa a cikin aikin da waɗannan jikuna.