"Dopamine" - me ke cewa? "Dopamine": wa'azi, aikace-aikace, farashin

Da miyagun ƙwayoyi "Dopamine" kama da wani crystalline foda na farin launi da kawai m wari na hydrochloric acid. Wannan nau'i shi yana a cikin nau'i na hydrochloride. "Dopamine" - wani abu mai narkewa a cikin ruwa da kuma barasa. An shafi alkalis, daban-daban oxidizing jamiái da na baƙin ƙarfe salts. Alamomi da kuma contraindications da amfani da miyagun ƙwayoyi "Dopamine", da wa'azi a kan ta yin amfani da an sanya shi a cikin littattafan da.

Yana nufin bayar da jiko bayani tattara.

pharmacological halaye

"Dopamine" - wani abu, wani neurotransmitter. A da na rayuwa Properties na dopamine ne precursor na adrenaline da noradrenaline. Da miyagun ƙwayoyi rinjayar da m rabe, da kuma a babban yawa kara habaka aikin α- da β-adrenoceptors. "Dopamine" aikin ne da nufin:

• kayan haɓɓaka aiki na gefe jijiyoyin bugun gini juriya;
• kara a systolic jini;
• ruri daga zuciya rate.
• ya karu cardiac fitarwa.
• qananan canji a zuciya rate.
• gagarumin oxygen wadata.

"Dopamine" kuma kara habaka da jini ya kwarara a cikin tasoshin na kwakwalwa, zuciya, kodoji, kuma hanjinsu. Karuwan glomerular tacewa kudi da kuma sodium tukar tumbi da koda.

"Dopamine" - mai azumi-aiki miyagun ƙwayoyi. Bayan 5-10 minti bayan i / v jiko aiki ƙare. A rabin rayuwa - kamar minti biyu. Rabin da abu interacts tare da mai gina jiki a cikin jini jini. Da miyagun ƙwayoyi wuce m metabolism tsari a cikin kodan, hanta da jini jini saboda da tasiri na Mao da catechol-O-methyltransferase zuwa Jihar m metabolites da aka rayayye samar da koda. A kwata na amfani da kashi da aka tuba zuwa norepinephrine a adrenergic jijiya sprouts. Saboda da aiki kawar ba wani jari na miyagun ƙwayoyi a cikin jikin mutum, ko bayan wani dogon lokaci na liyafar.

"Dopamine": aikace-aikace

Alamomi ga mai karɓa:

• Daban-daban iri buga, kamar wani traumatic, cardiogenic, postoperative, hypovolemic, endotoxin.
• M jijiyoyin bugun gini da zuciya rashin cin nasara.
• Low cardiac fitarwa.

"Dopamine" tare da cardiogenic tura musamman bukatun, shi qara tsokar contractile aiki.

Da miyagun ƙwayoyi ne gudanar intravenously. 125 ko 400 ml na biyar bisa dari bayani daga sodium chloride ko glucose bayani da ake bukata a 25 ko 200 MG bi da bi. Saboda haka, 1 ml na bayani samu 200 ko 500 .mu.g abu. Idan wani m ba za a iya gudanar da babban kundin na ruwa za a iya sanya more fi bayani haka cewa 1 ml na 800 micrograms ya "dopamine". Don yin wannan, kai 200 MG da 250 ml na bayani. A kudi na gabatarwar kai 1-4 ug / kg minti daya zuwa wani talakawan jiki nauyi na 70 kg (2 zuwa 11 saukad da na 0.05% bayani ko daga 1.5 zuwa 6 saukad da na 0,08% bayani). A warkewa sashi - daga 5 zuwa 9 MG / kg a 1 min. Sashi "Dopamine" 10-15 .mu.g / kg minti daya ne da amfani a vasodilation da hypotension. A gwamnati kudi za a iya ƙara zuwa 18 .mu.g / kg minti daya. A jiko faruwa ba tare da katsewa da rufe lokaci daga 2-3 hours zuwa 1-4 kwanaki ko ƙara. A kashi da rana ba wucewa 800 MG. Tare da gabatarwar "Dopamine" da aka gudanar ECG monitoring. Tabbatar da dalilin da kashi da kuma kudi na gwamnati ne bisa jijiya matsa lamba, zuciya rate, cardiac fitarwa, zuciya kudi da kuma diuresis. Idan hypotension ba bayyana, da kuma rage fitsari fitarwa, da kashi ya kamata a rage.

contraindications

Da miyagun ƙwayoyi ne contraindicated a taron na matsaloli kamar:

• arrhythmia.
• pheochromocytoma.
• prostatic hypertrophy.
• ƙulli glaucoma.

illa

A gabatarwar da dũkiyõyinsu a manyan allurai, wani babban matakin "Dopamine" zai iya sa illa, ciki har da:

• tsãwa;
• tachycardia.
• vasospasm.
• arrhythmia.
• take hakkin da numfashi kari.
• anginal da ciwon kai.
• psychomotor agitation .
• wasu bayyananen Adrenomimeticalkie mataki.

Tun da kawar da "Dopamine" shi ne aiki, da sama cututtuka bace idan runtse kashi ko yanke gwamnati da miyagun ƙwayoyi. Idan da kari an karya, shi wajibi ne don amfani antiarrhythmic kwayoyi, ciki har da "Verapamil", "lidocaine" da sauransu. Extravasation bayani "Dopamine" zai iya kai ga necrosis na subcutaneous adipose nama da kuma na fata.

tsõratar

"Dopamine" a lokacin daukar ciki Za'a iya wajabta kawai a lokacin da hakan ya zama tilas magani ga mahaifiyarsa, da warkewa sakamako ne mafi girma fiye da hadarin da tayin.

Sabo bayani ya kamata a yi m irin zane da kuma rasa extraneous ya dafa.

Lokaci daya da magani tare da sauran kwayoyi

Da miyagun ƙwayoyi iya dauka a cikin layi daya da cardiac glycosides da diuretics (msl, furosemide da sauran). Hypovolemic tura bukatar gabatarwar "Dopamine" tare da dukan jini, jini ko jini musanya.

Kada ku riƙi "Dopamine" a lokaci guda tare da "cyclopropane", Mao hanawa da kuma jamiái na maganin sa barci da Halo ( "Halothane" da sauransu).

Turmi mix halitta unacceptable da alkaline mafita daga sauran kwayoyi.

"Dopamine" - wani magani da aka yi amfani ne kawai a kan takardar sayen magani. Its farashin dogara a kan sashi da kuma yawan ampoules a wani kunshin, jere daga 80 zuwa 300 rubles da fakitin (5-10 ampoules).