"Naloxone": umarnin don amfani, sake dubawa, analogues

A aikin likita, akwai lokuta da amfani da kwayoyi ya haifar da overdose ko maganin mummunan aiki daga wasu kwayoyin halitta da kuma tsarin. Musamman sau da yawa irin wannan rikitarwa ana haifar da shirye-shirye na opioid. Don gaggauta cire su daga jiki, likitoci sunyi amfani da magunguna na musamman. Magungunan magani "Naloxone" wani magani ne wanda ke taimakawa wajen gyara halin da ake ciki da tsinkaye na kwayoyin cutar opioid. Mecece ce kuma menene ma'anar tasirinta? Bari muyi kokarin fahimtar waɗannan batutuwa.

Bayani na miyagun ƙwayoyi, abun da ke ciki da kuma tsari

Maganin magani na "Naloxone" don amfani yana nufin masu karɓa na opioid ne. Abubuwan da ke aiki shine naloxone hydrochloride. Abubuwan maganin da aka samo a kasuwar kasuwa ba haka ba ne, yana da maganin maganin injections da Allunan. Wadannan karshen suna da wuya a yi amfani dashi a aikin likita. Takardar Liquid don ƙwayar intravenous ko intramuscular, a akasin wannan, yana da bukatar gaske. A abun da ke ciki na bayani, a Bugu da kari ga aiki sashi, ya hada da wani sa na misali karin aka gyara, sodium chloride, tsarkake ruwa, Organic acid da kuma salts daga gare ta.

Ana samar da maganin "Naloxone" a cikin ampoules na gilashi mai haske tare da ƙarar 1 ml kowace. Tsaida aikin mai aiki a cikin kashi daya shine 0.4 MG.

Ana samarda samfurin a cikin kwakwalwan kwalliya na filastik filayen lacquered tare da toshe kayan aluminum ko ba tare da shi ba. Kowane irin wannan kunshin ya ƙunshi 5 ampoules.

An saka sauti guda 1 ko 2 a cikin akwati kwalliya tare da umarnin yin amfani da miyagun ƙwayoyi da kuma amfoule scarifier. Idan ana amfani da ampoules tare da zobe na musamman ko batu, ba a saka wukake don buɗewa cikin akwatin ba.

Hanyar aikin aikin magani "Naloxone"

Kamar yadda aka ambata a sama, shiri na Naloxone yana nufin masu tayar da ƙwaƙwalwar ƙwararrun masu karɓa na opioid. Wannan yana nufin cewa wakili zai iya hana wadannan masu karɓa, don haka kawar da aikin tsakiya da kuma na al'ada na mahadi daga ƙungiyar opioid. Bugu da kari, da miyagun ƙwayoyi a lokacin gudanar iya haifar da janyewar bayyanar cututtuka a marasa lafiya tare da miyagun ƙwayoyi buri.

Lokacin yin amfani da bayani na Naloxone, aikin aikin wanda aka bayyana a sama, sakamakon yana faruwa a cikin gajeren lokaci. Lokacin da intravenously gudanar miyagun ƙwayoyi daukan sakamako a 1-2 minti, intramuscular bayan minti 5. Lokacin tsawon yanayin magani a cikin wannan yanayin ya dogara ne akan hanyar jagorancin gudanarwa. Idan maganin ya warke cikin tsoka, magani yana da kimanin minti 45, da kuma jigilar intravenous - ba kasa da awa 4 ba.

Masana sun fi amfani da maganin Naloxone don maganin marasa lafiya. Tablets, ba kamar shi ba, suna aiki da ƙarfi kuma na ɗan gajeren lokaci.

Abinda yake aiki na miyagun ƙwayoyi ya ɓace a cikin hanta a cikin hanta. Lokacin da rabi ya ƙare yana ƙananan, kawai minti 30-80. Kusan kashi 70 cikin 100 na nauyin gudanarwa na Naloxone an cire shi daga kodan cikin kwana 3.

Babban amfani da miyagun ƙwayoyi "Naloxone" shi ne rashin yiwuwar kafa dogara akan shi.

Indiya don amfani

A waɗanne hanyoyi ne ake amfani da magani Naloxone? Umurnai don yin amfani da miyagun ƙwayoyi ya ƙunshi cikakken lissafin yanayi wanda amfani da shi yana da kyawawa sosai. Da farko, an umarce shi ga marasa lafiya bayan an fara aiki. Da amfani da kwayoyi "Naloxone" (analogues ma sau da yawa amfani a cikin postoperative zamani) , a cikin wannan yanayin yana taimaka wa sauri kawo haƙuri daga Jihar barci magani. Ana amfani da miyagun ƙwayoyi "Naloxone" don kawar da sakamakon cutar poisoning, analysic overdoses, barbiturates da benzodiazepines.

Sau da yawa, ana amfani da ita ta hanyar yin amfani da shi a cikin yanayin da aka haifi jariri a cikin yanayin da aka gabatar da analgesics na opioid a cikin mahaifi a lokacin bazawa. Yawanci, waɗannan yara suna da matsala tare da numfashi. Magungunan magani "Naloxone" yana kawar da su kuma yana taimakawa wajen kunna aikin motsa jiki. Ana amfani da wannan maganin sau da yawa kuma a matsayin kayan bincike idan akwai tuhuma da kasancewar magungunan magani a cikin mai haƙuri.

Ya kamata a lura cewa yanayin kawai don yin amfani da wannan kayan aiki shine shaida mai ƙarfi. Wannan shine dalilin da ya sa aka yi amfani da shi a aikin likita daidai bisa ga takardun likita kuma a karkashin kulawarsa.

Contraindications

Daga cikin contraindications ga amfani da miyagun ƙwayoyi "Naloxone" umarnin don amfani ambaci yanayin da wadannan da cututtuka:

• Kuskuren aiki ga abu mai aiki ko kuma daya daga cikin abubuwan da aka tsara na miyagun ƙwayoyi;
• Ciwon zuciya (Organic);
• Mai tsananin hanta da koda;
• Tsarin jiki na dogara akan opoid analgesics.

Ya kamata ya kamata a lura da miyagun ƙwayoyi ga mata masu ciki da dogara da miyagun ƙwayoyi, saboda bayyanuwar cututtuka, wanda ya bayyana a sakamakon gabatarwar maganin, zai iya cutar da yanayin tayin. Haka kuma ya shafi amfani a jarirai, wanda iyayenta a yayin cikar ciki sun yi amfani da kwayoyi masu guba.

A kowane hali, amfani da miyagun ƙwayoyi ya kamata ya wuce yiwuwar rikitarwa a cikin mai haƙuri. Muna tunatar da ku cewa ana amfani da takardar Naloxone kawai. Dokar da aka rubuta a cikin takarda ta hanyar likitancin likita yana nufin cewa mai haƙuri ba shi da mummunan ƙwayoyi game da amfani da wannan magani.

Hanyar aikace-aikace da sashi

Sashin maganin miyagun ƙwayoyi da kuma hanyar da aka gudanar shi ne ƙwararren ƙwararren ƙaddara ya danganta da yanayin halin mai haƙuri. A nan ne tsarin kulawa da ake yarda akai don Naloxone.

Wani overdose na kwayoyin cutar analgesic a cikin tsofaffi yana buƙatar gwamnatin 0.4 zuwa 2 MG na miyagun ƙwayoyi (1-4 ampoules) a cikin intravenously ko intramuscularly. Kashi ɗaya don yara ana lasafta bisa ga nauyin jiki, 0.005-0.01 MG / kg.

Domin cire haƙuri daga miyagun ƙwayoyi-jawo barci (a cikin postoperative zamani), da miyagun ƙwayoyi ne gudanar intravenously a cikin wadannan adadi: adult a wani kashi 0.1 MG bi ta sake bullo da dawo da maras wata-wata numfashi, yara - 0.01 MG / kg jiki nauyi don mayar da numfashi.

Ana magance matsalar ta hanyar intravenously, intramuscularly ko percussionally ga yara da aka haifa a adadin 0.1 mg / kg jiki nauyi sau daya.

Idan ya wajaba don gudanar da ganewar asali na dogara da miyagun ƙwayoyi, ana amfani da miyagun ƙwayoyi a cikin kashi 0.08 MG.

Ayyukan Mugunta

Daga cikin sakamakon mummunan amfani da miyagun ƙwayoyi "Naloxone" umarnin ya ambaci waɗannan sharuɗɗa:

• Nausea, watakila tare da roƙo don zubar;
• Ƙara karfin jini;
• Zuciya ta rudani;
• Ƙunƙwasawa da damuwa;
• Ƙãra sweating.

A cikin marasa lafiya tare da dogara na opioid, maganin miyagun ƙwayoyi na iya haifar da cututtuka, ciwo mai mahimmanci na localization, edema na mucosa na hanci, jijiyar wahala mai tsanani, ciwon ciki, ciki da jinji. Wadannan abubuwan mamaki suna dauke da hankula ga narcotic "watse". Sun wuce na minti mintina.

Analogues na Naloxone

Zai yiwu a maye gurbin miyagun ƙwayoyi "Naloxone" tare da magunguna irin wannan? Analogues na wannan kayan aiki a yau ƙananan. Wadannan sun haɗa da kwayoyi "Narcan", "Naltrexone", "Cyclosocine" da "Narcantin". Abubuwan da suka samo asali na Pharmacological, alamomi da takaddun shaida suna kama da wadanda aka samu a bayani na Naloxone da Allunan. Wannan shine dalilin da ya sa basu da kyau a yi amfani da su a gaban allergies zuwa wani fili irin su naloxone hydrochloride a cikin marasa lafiya.

Duk da haka, suna da nasarorinsu. Alal misali, miyagun ƙwayoyi "Naltrexone" yana dade na dadewa (kimanin awa 24) kuma ana saki da yawa a cikin nau'i na allunan ko capsules don magance baki. Ana amfani da shi don yin amfani da shi daga ƙwayar magungunan ƙwayoyi ta hanyar yin jigilar kayan shafa tare da bayani a karkashin fata.

Bayani game da miyagun ƙwayoyi

Daga cikin likitoci, miyagun ƙwayoyi "Naloxone" yana da kyakkyawan suna. A cewar su, yana taimakawa wajen ceton mutane da yawa marasa lafiya idan aka yi haɗari da ƙwayar cuta tare da kwayoyi daga kungiyar analgesics da / ko opioids. Duk da magunguna da kuma yawan adadin lahani, an yi la'akari da miyagun ƙwayoyi kamar inganci don amfani. Bugu da ƙari, yana tare da taimakonsa da za ku iya gano magungunan miyagun ƙwayoyi.