"Nebivolol": analogues, umarnin don amfani, reviews. "Nebivolol Sandoz"

Shirye-shirye daga kungiyar blockers suna yadu amfani da magani na da yawa zuciya da jijiyoyin jini cututtuka. Daga cikin wannan rukuni na kwayoyi da cika fuska kasaftawa "Nebivolol". Analogs wannan magani ma samu mai girma shahararsa saboda ingancinta. Wane irin magani, yadda yake aiki da kuma lokacin da za ka iya amfani da shi?

Menene wannan magani?

"Nebivolol" tana nufin wani rukuni na beta-blockers. Babban sakamakon wannan ne antihypertensive miyagun ƙwayoyi (miyagun ƙwayoyi rage matsa lamba). A sakamako ne lura da selectively tarewa da beta-rabe dake a cikin tasoshin (sakamako a kan beta-1-adrenergic rabe).

A halin yanzu yi amfani da "Nebivolol Sandoz."

Wannan magani ne mai hade da kunsha da dama isomers (D- kuma L-karba). Wannan hade da abubuwa da amfani ga ci gaban na asibiti sakamako. Daya isomer ne ke da alhakin ci gaba da antihypertensive mataki, yayin da na biyu yana da wani girma sakamako a kan zuciya rate.

Da miyagun ƙwayoyi bayyana gwada da kwanan nan, a tsakiyar karni na karshe. Tun daga nan, tartsatsi a cikin cardiac yanayi. "Nebivolol Sandoz" ne da miyagun ƙwayoyi da zabi a lura da hauhawar jini da kuma wasu zuciya kari cuta.

To, ta yaya aiki miyagun ƙwayoyi da kuma abin da hukuma ke da alhakin ta digestibility?

Pharmacokinetics

Mafi tunawa "Nebivolol Sandoz." Da miyagun ƙwayoyi ne da tunawa a cikin gastrointestinal fili. Za a iya dauka tare da abinci (sha ba rincabewa). Bioavailability ne in mun gwada low - game da 12 bisa dari. Idan zai yiwu, kauce wa raba da magani tare da barasa, tun da yiwuwar illa.

Da zarar a cikin jini jini, da miyagun ƙwayoyi ta ɗaure zuwa albumin da kuma siffofin insoluble gidaje. Wannan mamaye form kasancewa da miyagun ƙwayoyi ne game da 98 bisa dari, watau. E. ma duk tunawa "Nebivolol Sandoz". Its analogues ne guda hanyar da suka samu shiga cikin jini jini da kuma ba ya tuntube tare da gina jiki.

Kada internalize wani magani samu daga gastrointestinal fili da kuma kodan. Yana da aka sarrafa a cikin hanta, inda shi ta ɗaure zuwa glucuronic acid.

A rabin-rai da miyagun ƙwayoyi a marasa lafiya tare da kara metabolite ne game da wani rana. A cikin hali na jinkirin metabolism "Nebivolol" iya tara da za a kiyaye shi a jini jini domin game da 48 hours.

A tsokoki da miyagun ƙwayoyi ba tara cewa shi zai kawar yawan abin sama (da shi ne kawai zai yiwu a yanayin saukan ta yin amfani a marasa lafiya tare da koda ko hanta cuta).

alamomi

A wasu lokuta, duk da haka nada "Nebivolol" analogues da kwayoyi ko miyagun kwayoyi da irin wannan pharmacological mataki?

A farko nuni ga miyagun ƙwayoyi ne hauhawar jini. By da amfani da beta-blockers koma cikin ineffectiveness na yin amfani da ACE hanawa ( "Enalapril", "captopril"). Bugu da kari, "Nebivolol" yin amfani da endocrine hauhawar jini.

Wani, babu kasa muhimmanci nuni ga yin amfani da "Nebivolol" ne jijiyoyin zuciya da cututtukan zuciya. Tare da m exacerbations angina kuma don rigakafin irin wannan hare-hare, da kuma nuna "Nebivolol". Its analogues a cikin wannan hali zai iya zama ko tasiri fiye da m miyagun ƙwayoyi da kanta.

Yana hada da wani "Nebivolol" da kuma wani ɓangare na wani hade far domin lura da kullum zuciya maye. A wannan yanayin da shiri na taimaka wa kyautata na zuciya, rage xabi'a kuma afterload jam'iyya jiki, kazalika da rage a matsa lamba.

Za ka iya amfani da magani, kuma don rigakafin hawan jinni crises, kazalika a kan waɗanda suke yiwuwa ga atherosclerotic raunuka na cerebral tasoshin.

contraindications

Lokacin da ba lallai ba ne su yi amfani da "Nebivolol"? Umarnin don amfani da yawanci hada da duk waɗannan lokuta da aka gano a asibiti, a lokacin da baya da yin amfani da kudi ga ci gaban da daban-daban da rikitarwa. Saboda da karfi sakamako na antihypertensive wakili kamata ba za a wajabta a mai tsanani hypotension.

Da farko, shi ne haramta yin amfani da miyagun ƙwayoyi a m zuciya rashin cin nasara. Wannan shi ne saboda ganin cewa ya na da inotropic sakamako, wanda za a iya adversely shafi jiki saboda gazawar da zuciya aiki.

Tare da ci gaban pheochromocytoma an kuma haramta daga yin amfani da "Nebivolol." Umurnai na amfani na nuni da cewa a ba endocrine ƙari shiri za a iya amfani da kawai a tare da wani alpha tsoka mai amsa sigina shafi.

Ba lallai ba ne su sanya wani magani ga yara da kuma mutane da data kasance shafi tunanin mutum da kiwon lafiya da matsaloli.

"Nebivolol" An contraindicated a persons tare da mutum rashin ha} uri ga miyagun ƙwayoyi. A farko ãyõyi (tearing, shortness na numfashi) ya kamata nan da nan gushe amfani da miyagun ƙwayoyi da kuma su matsa zuwa wani hadari zaɓi.

illa

Kamar yadda da wani magani, "Nebivolol" yana da illa. Babban daga cikinsu akwai:

Juyayi tsarin - da ciwon kai, ciki, drowsiness, rashin barci, hallucinations, aka rufe da mãgãgi, juwa.

A gefe sakamako na narkewa kamar tsarin ne tashin zuciya, maƙarƙashiya, bushe baki da kuma amai. Zai yiwu bayyanar dyspeptic cuta, da kuma a lokacin coadministration tare da maganin rigakafi - dysbiosis.

The zuciya da jijiyoyin jini tsarin reacts zuwa bullo da wani "Nebivolol" bradycardia, dyspnea, edema, ci gaban m zuciya rashin cin nasara, atrioventricular block, Raynaud ta ciwo. Yawan abin sama na iya haifar da uncontrolled hypotension, wanda za a iya wuya ta auka da kuma syncope. A tsanani lokuta, bugu tasowa.

Side sakamako "Nebivolol" iya bayyana a matsayin erythematous rash, psoriasis.

A tsanani lokuta angioneurotic edema (angioedema). A milder lokuta, akwai ci gaban Indomitable sneezing ko tari.

Features na yin amfani da miyagun ƙwayoyi

Da miyagun ƙwayoyi ne amfani da hankali a cikin marasa lafiya da na koda insufficiency, da ciwon sukari mellitus, ko overproduction na thyroid ji ba gani. Kau da miyagun ƙwayoyi gudanar da hankali a kan 10-14 kwanaki. A farkon magani dole dole ne a sarrafawa BP da kuma HR. Idan zai yiwu, a lokacin da yin amfani da miyagun ƙwayoyi ya kamata a daina shan taba. Kafin mai zuwa tiyata tabbata domin faɗakar da anesthetist cewa haƙuri ne ta amfani da beta-blockers.

A lokacin dukan lokaci na yin amfani da miyagun ƙwayoyi ya zama dole don sarrafa jini sugar matakan, musamman a cikin masu ciwon sukari. Bugu da ƙari kuma, dole ne a kimanta tacewa ikon da kodan (musamman matakan creatine da urea), idan wani dogon lokaci da aka sanya "Nebivolol". Umurnai na amfani (analogs da irin wannan sakamako) yayi kashedin cewa zai iya ci gaba na koda gazawar lokacin da aka nada m miyagun ƙwayoyi.

An haramta amfani da miyagun ƙwayoyi zuwa yara a karkashin shekaru 18 da haihuwa da kuma mazan marasa lafiya da decompensated zuciya rashin cin nasara. Wannan haramta ne da farko saboda yiwuwar ci gaban rayuwa cuta da kuma bayyanar da wani matsin lamba matsala.

Tun lokacin amfani da miyagun ƙwayoyi iya ci gaba dizziness, ba lallai ba ne su sanya direbobi da kuma likitoci.

Amfani da miyagun ƙwayoyi da ciki

Manufar wannan magani don mace mai ciki kawai zai yiwu bayan shawara da likitan mata da kuma ilimin. Da miyagun ƙwayoyi ne da wuya amfani saboda da mummunan tasiri a kan uwa da yaro.

Da miyagun ƙwayoyi ne ba kawai a cikin yanayin da matsananci larura, tun da shi ne zai yiwu ci gaban bradycardia, hypotension, da qarancin ruwa da numfashi inna, seizures.

Kwanaki uku kafin sa ran haihuwa wajibi ne ta yi watsi da yin amfani da wannan magani. Idan wannan shi ne ba zai yiwu, a cikin farkon zubar lokaci na bukatar mai da hankali saka idanu na masu juna biyu da kuma yaro kiwon lafiya. Tabbata a lokacin da yin amfani da kashin baya maganin sa barci, da anesthesiologist dõmin ya yi gargaɗi mai gudana magani blockers.

Ya kamata a tuna cewa a kan bango na yin amfani da miyagun ƙwayoyi iya ci gaba fetal hypoxia. Teratogenic sakamako daga cikin miyagun ƙwayoyi ba a tabbatar ba, amma akwai lokuta na irin wannan illa da kan tayin.

Idan har yanzu kana ciki sanya "Nebivolol" wa'azi a kan aikace-aikace yayi kashedin cewa zai yiwu murdiya na warkewa mataki da miyagun ƙwayoyi a nada tare da igiyar jini magnesium.

Hulda da sauran shirye-shirye magani kungiyoyin

Raba wani "Nebivolol" da kuma antiarrhythmics aji 1 zai iya kai ga ya karu korau inotropic sakamako. Zai yiwu ga cigaban AV block. A irin wannan sakamako ne lura idan lokaci daya amfani da alli tashar blockers da kuma "Nebivolol Sandoz."

Umarnin danganci yayi kashedin cewa idan gudanar intravenously yiwu sakamakon bugun zuciya (bayar da miyagun ƙwayoyi ne gudanar a tare da tare da "Verapamil"). A wannan yanayin, bukatar gaggawa cardioversion amfani cardioversion.

Akwai wani gagarumin hadarin mai tsanani hypotension a lokacin da gudanarwa da miyagun ƙwayoyi zuwa "nitroglycerin".

A lokaci daya nada sympathomimetic da kuma "Nebivolol" na taimaka wa zalunci na karshe.

A hada yin amfani da kwayoyi don maganin sa barci iya kai wa ga wani kaifi digo a cikin jini, wanda zai bauta a matsayin nuni ga inji samun iska da kuma amfani da hawan jinni kwayoyi.

Lokacin da gudanarwa da miyagun ƙwayoyi iya ci gaba insulin hormone yawan abin sama da voye asibiti ãyõyin qarancin ruwa.

sashi

Saboda haka abin da kuke bukatar amfani da wannan allurai da miyagun ƙwayoyi, wajen samar da zama dole asibiti sakamako? Idan ka yi amfani da "Nebivolol Sandoz", umurci manual yayi da wadannan irin dosing.

A mafi kyau duka kashi na fara tasawa ne 20 MG da rana. Da miyagun ƙwayoyi da ake amfani a ciki da safe a kan komai a ciki. Matsakaicin sakamako daga cikin sashi amfani ne ci gaba ta hanyar daya ko makonni biyu da fara magani. Idan dole, da kullum adadin magani iya karu zuwa 10 MG. Ga mazan marasa lafiya, matsakaicin kullum kashi ne 5 milligrams, kuma mafi kyau duka domin lura - 2.5 milligrams kowace rana. Domin ciki adadin shirye-shiryen da aka zaba bisa ga na asibiti da ãyõyinMu, kuma jiki nauyi. Shi ne mafi kyau don amfani mai "Nebivolol Sandoz" (5 MG) Allunan.

A hali na take hakkin na hanta ko kodan ne mafi alhẽri ta yi watsi da yin amfani da "Nebivolol" ko sanya shi ga m sashi.

Lokacin da concomitant gwamnatin sympathomimetics da kuma "Nebivolol" yiwu potentiation sakamako, sa shi yiwuwa a rage yawan garatin kashi na miyagun ƙwayoyi.

Amfani da miyagun ƙwayoyi a karami allurai yana da wani sakamako a kan jiki. Iya samar da ragowa da miyagun ƙwayoyi rabe da dadewa gwamnatin low allurai da miyagun ƙwayoyi.

miyagun ƙwayoyi analogues

Shi ne ba ko da yaushe zai yiwu a sami magani a dole shiri, don haka dole ka koma ga yin amfani da analogs. Saboda fadada daga cikin kasuwar magunguna, samun irin wannan kayayyakin ba wuya. Abin da magunguna iya maye gurbin "Nebivolol"?

Analogs (ma'ana) daga cikin shirye-shiryen su ne kamar haka:

• "Binelol".
• "Nebivator".
• "Nebivolol Canon".
• "Nebivolol STADA".
• "Nebivolol teva.
• "Nebikar".
• "Nebilet".
• "Nebilong".
• "Hod palates."

Kowace daga cikin wadannan kwayoyi na da kyau da kuma mummunan fasali. Wasu daga cikin su suna inganta maimakon classic "Nebivolol." Umurnai na yin amfani da kowanne daga cikin wadannan, duk da haka, yayi kashedin game da mafi korau effects. Saboda haka, domin sanin tambaya, wane irin magani ne mafi alhẽri, za a iya kawai taimake m da m likita.

Ba lallai ba ne a yi amfani da wadannan kudi a kan nasu, ba tare da tuntubar likita, saboda kawai a cikin wannan hanya za a iya muhimmanci worsen hãlãyensu da kuma cutar da duka biyu su kiwon lafiya, da kuma kiwon lafiya na da abokai da iyali.

Reviews na shirye-shirye

Mutane da yawa marasa lafiya ne rayayye yabe a kan irin wannan magani forums a matsayin "Nebivolol Sandoz." Sharhi kan shi an samu yawanci tabbatacce, tun da miyagun ƙwayoyi taimaka wajen warkar da ko kama da bayyanar cututtuka da cutar, mafi yawan marasa lafiya.

Ko da yake illa mallaki by da miyagun ƙwayoyi, an dauke daya daga cikin key a lura da dagagge matsa lamba da kuma cardiac insufficiency.

Kuri'a na tabbatacce feedback, kuma yana da tsabta "Nebivolol." Analogues daga cikin miyagun ƙwayoyi zuwa wani more dace, wani - kasa, don haka da cewa da ra'ayoyi da marasa lafiya bambanta. Dole ne ka kuma yi la'akari da comorbidities, wanda zai iya muhimmanci rage sakamakon da miyagun ƙwayoyi.

Ya kamata ka shakka la'akari da shekaru da lafiya bi da tare da wannan magani.

Dukkan betaadrenoblokatorov amfani da cardiac marasa lafiya, da fari shi ne "Nebivolol" (analogues). Reviews wannan magani sa shi yiwuwa a kira shi da mafi tasiri miyagun ƙwayoyi da wannan magani kungiyar.