"Torasemide": umarnin don amfani. "Sandoz Torasemide": price, location, reviews

"Torasemide" - wani zamani iko diuretic miyagun ƙwayoyi da cewa shi ne cikakke ga dogon lokacin da far cututtuka hade da bayyanar edema. Saboda karami yawan asibiti muhimmanci illa, da fāɗin da warkewa amfani more. Shi ne mafi aminci zuwa wasu madauki diuretics, kuma yana da mafi shaida. A lura da cututtuka daban-daban da sashi ne modified. Har ila yau, shi ne zartar a hali na insufficiency na koda aiki ko da a low tacewa gudu glomeruli nephrons.

Gurbin "torasemide"

"Torasemide" kamar yadda wani wakilin madauki (gishiri) kungiyar diuretics aiki a cikin luminal ɓangare na epithelium na tubules na nephron a hawa rabo daga madauki na Henle. Exerting wani mai hanawa sakamako a kan hadin gwiwa kai na potassium ions da sodium chloride, shi muhimmanci rage da electrochemical yuwuwar a surface epithelium na nephron. Kawancen sakamakon shi ne tashin hankali na ion kai sodium reabsorption daga primary fitsari, wanda qara diuresis.

Kusan duk madauki diuretics sa electrolyte disturbances saboda da karfi da tasiri reabsorption na potassium ions, sodium, magnesium, kuma chlorine. "Torasemide" zuwa wani karami har shafi da zaɓi na potassium da magnesium, saboda abin da wani yawa ƙananan faru na arrhythmias, anorexia, maƙarƙashiya, tsoka rauni. Har ila yau, da miyagun ƙwayoyi zuwa wani kadan har tubalan samuwar thromboxane A2, mikawa tasoshin. Ya kuma tubalan aldosterone rabe infarction, inhibiting tafiyar matakai na fibrosis na zuciya tsoka.

shaidar

A haɗe zuwa da miyagun ƙwayoyi "Torasemide" umurci manual ƙunshi bayanai game da cutar, wanda ya yi amfani da magani. "Torasemide" da aka nuna ga:

• pathogenetic lura da jijiya hauhawar jini resistant zuwa far da haduwa da ACE hanawa (ARBs) thiazide diuretics.
• lura da kullum zuciya rashin cin nasara, a shafe Sistem obalodi da'irori.
• symptomatic magani na kullum na koda gazawar, ciki har da tace a low gudun (kasa da 20 ml \ min).
• symptomatic magani daga hanta (tare da hade hypoalbuminemia) edema matsayin madadin su "Furosemide".

Lokacin da hauhawar jini "Torasemide" analogues da generics suna amfani ne kawai bayan gazawar da thiazide diuretics. A miyagun ƙwayoyi za a iya gudanar da shi ne dogon saboda kananan yawan asibiti muhimmanci da kuma hatsari illa a koda gazawar. Wadanda daga "torasemide" ne sosai kasa da cewa na "Furosemide".

Umarnin don amfani

Bisa ga na asibiti jagororin ga miyagun ƙwayoyi "Torasemide" umurci manual qunshi da halaye na miyagun ƙwayoyi dosages ake bukata domin magani da kuma gyara daga cikin manufa cuta. Cikinsa da miyagun ƙwayoyi da kanta ne samuwa a Allunan dauke da wadannan sinadaran: 2.5 MG, 5 MG, 10 MG, 20 MG, 50 MG, 100 MG, 200 MG.

Don dauki da miyagun ƙwayoyi a kan wani kwamfutar hannu da safe, ko da kuwa ci abinci. Domin wadannan allurai da miyagun ƙwayoyi "Torasemide" farashin daban-daban: shi ne ƙananan a mafi ƙarancin kashi kuma mafi girma a kalla. Bisa ga kaddarance data, 30 Allunan na da miyagun ƙwayoyi a 5 MG ne game da 400 rubles. Lokacin da samun wannan kashi ake rarraba kamar haka bisa ga alamomi:

• a lura da hauhawar jini dauka 2.5 - 10 MG / rana.
• samu 10-20 MG / rana ga na kullum zuciya maye.
• kullum na koda gazawar - 50 MG ko fiye.
• hanta gazawar bukatar mutum kashi sabawa.

Gefen Gurbin "torasemide"

A haɗe zuwa da miyagun ƙwayoyi "Torasemide" umurci manual ƙunshi bayani game da mahara illa. A warkewa kashi, watau har zuwa 200 MG da rana na kara hadarin thromboembolic rikitarwa, cardiac ischemia, cerebral. Yana kara hadarin dõgẽwa ischemic kai hare-hare da kuma tsokar zuciya infarction, na huhu embolism, arrhythmias. Akwai kuma yiwuwar faru na rashin lafiyan rashes ko amya lokacin da haƙuri da predisposition.

"Torasemide" wani lokacin sa tashin zuciya ko amai, da wuya lũra dyspepsia, zawo. Aka bayyana ruwan dare lokuta na pancreatitis a lokacin jiyya da "torasemide". Kuma ya karu hanta transaminases, na nuna hanta yawan guba daga cikin miyagun ƙwayoyi a high allurai. Wani lokaci marasa lafiya damu game da kadawa a cikin kunnuwansu, Heart hangen nesa.

Lokacin da ka karɓi wani mai guba kashi a bunkasa jihar yawan abin sama da kadan bayyanar cututtuka. Yawan abin sama yana tare da wani asarar ruwa a cikin fitsari: diuresis tsawo da kuma m, na iya ci gaba hypotension, jijiyoyin bugun gini auka, aka rufe da mãgãgi, bugun jini, cerebral ischemia a bango.

Contraindications da kuma gazawar aikace-aikace

Drug "Torasemide" analogues da Generic kwayoyi ba za a iya amfani da su a gaban cikakkar contraindications. Waɗannan su ne rashin lafiyan dauki ga miyagun ƙwayoyi ko binders. "Torasemide" haramta amfani a na koda gazawar da anuria, hanta gazawar yayin da a Jihar hanta coma, tare da tachyarrhythmias. Contraindicated ci a lokacin lactation da ciki, kazalika da kasa da shekaru 18 da shekaru, hypersensitivity zuwa sulfonamides.

Gefen da kuma hada effects "torasemide"

A lura da hauhawar jini kwayoyi "Torasemide" iya yin mummunan tasiri a kan hanya na gout. Tun da proximal tubules na nephron aiki abu ingested da aiki da sufuri, akwai m hanawa na tukar tumbi da uric acid. Kan bango na yin amfani da "torasemide" high yiwuwar hyperuricemia kuma m gout.

Medicament "Torasemide" halin da takamaiman mataki a kan proximal rabo daga tubular epithelium madauki na Henle. Saboda da karfi diuretic sakamako da kuma electrolyte rashin daidaituwa wannan yana sa alama daga asibiti muhimmanci pharmacological interactions. Su ne m, bai isa a kula da kyawawa. Daga cikin hatsari da kuma muhimmanci ne:

• high kashi (50 MG / rana) "torasemide" a lokacin da amfani a tare da platinum shirye-shirye kara habaka da yawan guba na karshen.
• manyan allurai "torasemide" (50 MG / rana) kara nephrotoxic da ototoxic effects na aminoglycoside maganin rigakafi.
• a cephalosporin maganin rigakafi, a lokacin da amfani tare da "torasemide" a wani kashi na 50 MG / rana bayyana dukiya nephrotoxicity.
• salicylates tare da "torasemide" (50 MG / rana) halin neurotoxicity.
• "Torasemide" kan bango na dangi hypokalemia qara laulayi na myocardium zuwa cardiac glycosides, kara da inotropic da antiarrhythmic sakamako, kara hadarin yawan guba.
• hadarin hypokalemia an karu da concomitant amfani "torasemide" tare da corticosteroids ko Saline laxatives.
• "Torasemide" kara habaka sakamakon "theophylline" curariform da tsoka relaxants.

So effects na hada amfani

Na so effects cewa bukatar saka idanu, shi ne wani karu a jini a lokacin jiyya da ACE hanawa. "Torasemide" saboda kau da ruwa rage da hydrostatic matsa lamba na da jini lũra a drop a jini. Wannan al'amari ne mai muhimmanci a lura da hauhawar jini da kuma na bukatar gyara daga cikin kashi na ACE hanawa. Haka kuma, a lura da far-resistant hauhawar jini da kuma a hade da wani ACE hanawa "torasemide" yale mu mu cimma daidaita jini a 90% da marasa lafiya.

A lura da na kullum zuciya gazawar asibiti muhimmanci sakamako na rage vasoconstrictor aiki na catecholamines. Zuciya a kan wani bango diuretic far "torasemide" weaker amsa wa stimulatory sakonni adrenaline da noradrenaline. Duk da haka, da wannan sakamako na rage tasiri na epinephrine kuma norepinephrine a lokacin farfado da.

Illar da hulda

Akwai Effects hanawa inganci a lokacin da a hade tare da wasu abubuwa. A musamman:

• shirye-shirye na bile acid sequestrants rage kama "torasemide" na hanji, yanã raunanar da sakamakon da karshen.
• narcotic analgesics (NSAIDS) rage tasiri na "torasemide".
• "Probenecid" saboda karawa matakai urikozuricheskih damuarn selection "torasemide" a cikin lumen na tubules, Munã rage ingancinta.

Comparative halaye "torasemide"

A shirye-shiryen "Torasemide" analogs iya zama aji, sanadin motsi da kuma generics. Daga cikin aji wakilta analogues: "Furosemide", "bumetanide," "ethacrynic acid". A kwatanta da "Furosemide" "Torasemide" ne halin da wani jinkirin farko na aikin da kuma wani karin shafe tsawon sakamako dangantaka tare da karin diuresis. Samar da diuretic sakamako ne kusan guda ƙarfi kamar cewa da "Furosemide" "Torasemide" yana da m illa hade tare da m electrolyte rashin daidaituwa.

"Bumetanide" ne halin da wani ko da karfi diuretic dukiyar da ake dangantawa da yawa illa. Ethacrynic acid yana da ƙananan farko kudi diuretic sakamako da kuma yana da wuya amfani da miyagun ƙwayoyi. A pharmacokinetics da miyagun ƙwayoyi "Torasemide" sake bitar kwararru gane wani muhimmin batu. Da miyagun ƙwayoyi yana da kaddarorin "irinta": diuresis bayan karawa ta allocating sodium ba compensatory ta riƙewa.

Pharmacokinetic analogues "torasemide"

The "Torasemide" magani mai shiryarwa bayar da bayanai a kan ta aikace-aikace a cikin marasa lafiya da na jijiya hauhawar jini. Tare da miyagun ƙwayoyi, domin lura da hauhawar jini da kuma ma amfani thiazide diuretics, potassium-ƙwauro. Kuma thiazide saboda sannu a hankali zuwa da kuma shafe tsawon diuretic sakamako ne kwayoyi na zabi.

A dangane da wadannan pharmacokinetic siffofi analogues ga shirye-shiryen "Torasemide" aikace-aikace na iya zama da wadannan: da magani daga hauhawar jini, resistant ga daidaitattun far da ACE hanawa haduwa (ko angiotensin tsoka mai amsa sigina shafi) da thiazide. Har ila yau, "Torasemide" da ake amfani a kullum na koda gazawar da magani tare da rage tacewa iya aiki.

Generics "torasemide"

A shirye-shiryen "Torasemide" umurci manual, analogues, alamomi da kuma contraindications cikakken faye hali ta babban sakamako - ƙara diuresis. Haka kuma, irin wannan mataki yana da asali miyagun ƙwayoyi da kuma Generic. A karshen dauke da wannan yawan "torasemide", amma samar karkashin sauran iri sunayen.

Mafi shahara ne: "Britomar", "Diuver", "Sandoz Torasemide", "Trifas", "Torcida", "Trigrim". A lokacin m gwaji pharmacological jamiái gagarumin bambance-bambance aka lura tsakanin su a Rasha. Kowane na sama formulations cikakken sauya wasu daga cikinsu.

Tattalin arziki da al'amurran da magani "torasemide"

A lura da hauhawar jini a lokacin da thiazide diuretics ne m, a hade tare da ACE hanawa (ko ARBs), za a iya gudanar da miyagun ƙwayoyi jiyya "Torasemide": umarnin don amfani da jayayya guda kashi a lokacin da rana. A wata-wata kudin magani ne game da 400 rubles a farashin 60 Allunan na da miyagun ƙwayoyi game 760-800 rubles. Don kwatanta, da wata-wata farashin magani "Furosemide" da wuya wuce 20 rubles. Amma karshen ga m lura da hauhawar jini ne na kadan amfani.

A kullum zuciya maye da edema na biyu da'irori dabam dabam kudin na wata-wata magani "Furosemide" ne game da 20-30 rubles. A shirye-shiryen "Torasemide" Farashin ne 10-15 sau mafi girma. A karshen yana da wani m sakamako, cewa shi ne m qara tukar tumbi da fitsari a cikin ta farko hours na liyafar. The "Furosemide" halaye na baya: shi ƙwarai qara adadin fitsari a cikin sa'o'i biyu da sauka a hankali weakening na fitsari fitarwa.

A sakamakon haka, employable marasa lafiya tare da hauhawar jini ko na kullum koda insufficiency ko Sistem basira tambaya "Torasemide" wa'azi (da farashin nuna a bisa) a kan aikace-aikacen da ya ƙunshi bayani game da gagarumin kayan haɓɓaka aiki na diuresis a karo na farko na liyafar. Duk da haka, da ritaya shekaru na marasa lafiya a cikin rashi na bukatar zo aiki, fitsari fitarwa gudun ne kusan m. Yana da bã ya halittar matsaloli, sabili da haka ba ka damar sami cheap aji analogue - "Furosemide".