Total Ige. Jini gwaje-gwaje domin total Ige

The mutum rigakafi da tsarin ne quite bambance bambancen a tsarin. Ya kunshi wasu gabobin (misali, saifa, thymus, Lymph nodes) da kuma sel (leukocytes, lymphocytes). Babban rawa aka buga kagaggun Kwayoyin cewa haduwa musamman abubuwa - immunoglobulins. Su ke da alhakin ci gaba da rigakafi da kuma rashin lafiyan halayen.

A ci gaban da alerji taka wata rawa ta musamman Ige

Menene wannan abu

Ige - musamman kwayoyin wanda aka located a cikin submucosal Layer na da yawa tsokoki da kuma gabobin. Yana yana da babban dangantaka zuwa yawa Kwayoyin na jiki wanda aka yawanci daure. A jini ne kusan ba a gano a cikin free form.

A cikin mutane, wannan sulusi da murabba'i immunoglobulin alhakin rashin lafiyan dauki (irin 1 hypersensitivity halayen).

A lokaci a lokacin da rabin decomposes a gaban magani immunoglobulin - 3 days. Fiye da lokaci ya ke a jikin tantanin (zai fi dacewa obese baje zubar a kan Bronchial mucosa surface) - game da makonni biyu.

A matakin na wannan abu dabam cikin rayuwar. A al'ada manya jimlar Ige ne game da 20-100kE / l. A yara, taro ne da yawa kasa - a jarirai shi ya aikata ba (mulki 0-3). a matsayin maida hankali ƙaruwa hankali girma.

Dalilan da karuwa a matakin na rashin lafiyan immunoglobulin

Kamar yadda da wani kudi, matakin da kwayoyin za su iya bambanta dangane da yanayin da ciki yanayi.

Total Ige tãyar da kullum a cikin cututtuka irin Bronchial fuka, atopic dermatitis da kuma rashin lafiyan rhinitis. Wadannan cututtuka fara bayyana kanta a lokacin kuruciya da kuma sau da yawa zurfi a cikin manya. Kara matakan immunoglobulin nuna cewa jiki yana sensitized (yana da babban ji na ƙwarai da hadarin tasowa wani alerji) to da yawa allergens (abubuwa da za su iya haifar da wani rashin lafiyan dauki).

A total Ige yara ya karu da yawa a cikin cututtuka, da kuma ba kawai ga sama. Irin cututtuka sun hada da rashin lafiyan aspergillosis, helminthiasis, Ayuba ciwo, Wiskott-Aldrich ciwo, da sauransu. D.

Kara taro na immunoglobulin a jariri ya nuna babban hadarin da bunkasa atopic cutar tun farko kwanaki na rayuwa.

Low matakan rigakafi da abubuwa

Rage matakin na antibodies za a iya lura a yawa cututtuka, tare da wani rauni na thymus (a cikin shimfiɗar jariri) ko tsari immunosuppression, da Sanadin wanda za a iya kafa.

bargo da kuma hanta (a cikin yara) take kaiwa zuwa da cewa ba kawai rage total Ige, amma sauran immunoglobulin sulusi da murabba'i. Wannan shi ne saboda gaskiya wannan ya shafi babban Kwayoyin alhakin kira daga cikin wadannan abubuwa - B-limoftsity.

Babban aiki na B Kwayoyin - kira na aiki abubuwa, da shan kashi a halakar waje jamiái.

A raunuka (hepatitis, radiation, ƙari tsari, m rauni musculoskeletal) da kuma lalacewar auku a cikin jam cell, sakamakon taimaka wa rage matakin duk immunoglobulins. Yana ba da wani togiya, da kuma cewa jimlar Ige da aka rage.

Daya daga cikin mafi m dalilai domin karkatar immunoglobulin E matakin ne wata cuta, ataxia telangiectasia.

Ginshikai na rashin lafiyan halayen

Ta yaya ci gaban da wani rashin lafiyan dauki lalacewa ta hanyar wannan aji na immunoglobulins? Idan dagagge total Ige, yana yiwuwa su tsayar da wadannan hoto (mafi daukan hankali misali na farko da irin rashin lafiyan halayen - asma).

Da farko, da ji na ƙwarai da kwayoyin, m. F a mayar da martani ga shigarwa cikin jiki na antigen takamaiman immunoglobulin samarwa na faruwa data. Suna hawa ta hanyar jini a cikin jini na numfashi tsarin (yafi na bronchi) da kuma ajiye a cikin mucosa. Maimaita lamba tare da antigen immunoglobulins, wanda aka riga "zaune" da mucous membrane, haifar da kunnawa da takamaiman sel (mast da finjãlin giya). Su, bi da bi, samar da kumburi shiga tsakani - histamine, serotonin, heparin, wanda da constrictor mataki (haddasa ƙanƙancewa na m tsoka Kwayoyin na mucous membrane). Wannan rage lumen na bronchi, wadda take kaiwa zuwa babba matsaloli exhaling. Kamar wancan ci gaba asma.

analysis immunoglobulins

Lokacin na farko da bayyanar cututtuka na allergies zama tabbatar da yin immunnogrammu. Yana da wani da ake kira jerin duk dauke a cikin jini immunoglobulins, da su maida hankali.

Don bincika da venous jini da ake bukata. Bar kima yawanci ba a cikin safe, da azumi, a sakamakon ingestion iya tsokana allergiepodobnuyu dauki da kuma samun m gwajin sakamakon.

Tattara jini za a iya adana don har zuwa 8 kwanaki a karkashin wani yanayi.

Amfani da musamman analyzer kayyade matakin na immunoglobulins, da kuma riga a kan tushen da wani canji a cikin adadin za a yi da cutar.

Lokacin ganowa dagagge matakan immunoglobulins (musamman nuni total Ige yaro) ya kamata a da ake zargi alerji zuwa wani antigen, wadda ya kamata a da za'ayi epicutaneous gwajin. Rage iya magana game da raunana rigakafi.

Features na immunoglobulins a yara

A cikin jiki da tayin fara nuna immunoglobulin E a cikin tsawon makonni 11. A lokaci guda su ne don haka babban abin da ba su wuce ta cikin mahaifa da kuma zama a jikin yaro. A total Ige a cikin yaro hankali fara girma na tsawon shekaru 15, tare da ci gaban fairly gaggãwar. A shekaru 15, yawan E-immunglobulinov sulusi da murabba'i ne game da 200kE / L kuma akwai wata rage zuwa taro na 18 zuwa 100, wanda shi ne al'ada kudi ga ya fara tasawa.

Lokacin da high yawa daga immunoglobulins a cikin igiyar jini ya kamata a da ake zargi da yiwuwar ci gaba da atopic dermatitis ko asma.

Bisa ta gabatar ba, ya bayyana sarai cewa mafi hatsari shekaru domin cin gaban allergies a cikin yara ne tsakanin 10 zuwa shekaru 15. A total Ige a cikin yaro quite kula daban-daban antigens, kuma a lokacin da "matasa" shekaru, a kan bango na hormonal canje-canje, da ji na ƙwarai ne ya karu da sau da yawa.

Canza immunoglobulin matakai a cututtuka daban-daban

immunoglobulin taro iya bambanta dangane a kan yanayin da cutar.

• Mutane da yawa atopic cututtuka yawanci faruwa tare da wani gagarumin karuwa a cikin adadin immunoglobulin E, ko da yake akwai lokuta da cutar tare da al'ada da matakan wadannan sunadaran kwayoyin.
• Bronchial fuka zai iya faruwa ba tare da kara matakin kwayoyin halitta, idan akwai ji na ƙwarai to daya kawai allergen.
• Total Ige, yaro iya ƙara a cikin hali na helminth cututtuka. A a layi daya, da karuwa a eosinophil matakan kiyaye.
• Daya daga cikin mafi tsanani cuta ne wuce-wuri-Ige-ciwo. Lokacin da yana yiwuwa su kara wannan matakin na fiye da 2000 kwayoyin (har zuwa 50 000kE / l). Cutar da ake tare da m rashin lafiyan halayen, urticaria, rashin lafiyan mafi abubuwa. Wannan jiha na bukatar m karatu da kuma nazarin commissioning kamata a da za'ayi maza maza.

A hatsari na babban taro immunoglobulin E

Kamar yadda aka ambata, high matakan da wannan kwayoyin ya nuna ci gaban da allergies. A mafi hatsari ne ƙwarai to mafi allergens, kamar yadda a cikin wannan hali, wani alerji zai iya ci gaba a kusan duk wani abu.

Matsanancin yawa daga wadannan kwayoyin a cikin mucous membrane ya shafi ci gaban irin wannan yanayi mai hadarin gaske kamar angioedema (Quincke ta edema). Domin ta dace ganewar asali (tun jihar tana nufin rãyuwar-barazanar), tabbata a gudanar da wani jini gwajin. Ige (total) a cikin shi ba za a iya gano, amma ta ci gaba ne da ake zargin a cikin hali na babban taro na lymphocytes.

A tsanani allergies iya ci gaba necrosis na mucous membrane. Yanayin ne mai hadarin gaske saboda shi ne zai yiwu ci gaban maye, kazalika da samuwar fistulas tsakanin bronchi da kuma huhu nama, ci gaban pneumothorax da pneumoperitoneum.

faci gwaji

A kayyade high yawa daga wadannan kwayoyin kamata a da za'ayi a hankali a cutaneous jini magani samfurin. Su ba ka damar sanin da ji na ƙwarai to takamaiman allergens da kuma hana ci gaban allergies a nan gaba.

Babban nuni ga wadannan samfurori ne immunoassay - Ige janar shi za a kyautata. Bugu da kari, a tarihin ya kamata a kalla daya rashin lafiyan hari (ko da yake shi ne zai yiwu, da kuma bincike binciken a kan hadarin tasowa allergies, ko a lokacin da na asibiti manifestations aka lura).

A samfurin da aka za'ayi amfani tsarma mafita daga allergens (bincikowa - suspensions allergens - quite mai yawa, da damar don gano ainihin allergen cewa zai iya fararwa da ci gaban da wani rigakafi martani). Dole kafin nazarin dauki jini ga Ige total, kazalika da gudanar da cikakken jini count. Ake bukata kafin analysis, don samar da wani sa na gaggawa shirye-shirye Case shi tasowa unforeseen wahala daga hanya.

da bukatar gudanar da bincike

Me ya sa yake cewa immunoglobulin ne don haka da muhimmanci a ƙayyade lokaci?

Yawancin lokaci shi ne babban ma'aunin da na rigakafi da tsarin ya fara rashin lafiyan halayen (a cikin taron cewa taro ya karu), don haka ya kamata ka dauki cikin matakan kare jiki daga dukan rikitarwa.

Idan rajista (Ige shared) kudi, shi ya kamata ba nan da nan a ji dadin jini. Kamar yadda aka ambata, da al'ada dabi'u za a iya lura a wasu cututtuka, saboda haka tabbatar da gudanar da faci gwaji ya yi mulkin fitar alerji diagnoses (idan dace asibitin).

Karkashin rage immunoglobulin hadari ne cewa tsarin na rigakafi ba zai iya amsa wa mai shigowa antigen saboda abin da za a iya rasa mafi tsanani cuta, abu don komowar sakamakon.

Shi ne saboda duk wannan shi ya kamata ya yi la'akari da muhimmancin da wannan kwayoyin, kuma ba ya shagala da definition.