Creatinine shine al'ada a jini da fitsari. Muhimmiyar muhimmancin samfurin

Creatinine - daya awo na jini sunadarai da urinalysis. A cikin ilmin lissafin asibiti, an ƙaddara shi musamman a binciken nazarin filtration da haɓaka kodin kodan. Ga likita, halittar halitta, al'ada ko farfadowa na pathological yayi magana akan kundin. Amma bari mu fara nazarin irin nau'in abu, da kuma yadda aka kafa shi cikin jiki.

Daga litattafan rubutu akan biochemistry, za ka iya koyi cewa creatinine yana daya daga cikin abin da ake kira samfurori na karshe na metabolism. An kafa shi daga gina jiki mai gina jiki, wadda ke aiki a matsayin tushen makamashi don musculature. A cikin tsokoki, mahalicci yana cikin hanyar fili wanda ake kira creatine phosphate. Tare da raguwa na tsoka, mahaifa phosphate yana ba da makamashi, kuma ya raguwa zuwa samfurori na karshe - cutinine, ruwa da phosphorus. Saboda haka cikin jiki ya bayyana Halitta. Halinta ya dogara da adadin ƙwayar tsoka. Saboda haka, a cikin maza, halittar halittar jini, al'ada, ita ce mafi girma fiye da na mata.

Sakamakon karshe na tsarin tsarin sinadarin sunadarai an cire shi ta hanyar kodan da fitsari. A cikin renal glomeruli, haɓaka daga jini an cire shi kuma ya shiga cikin ƙananan gogewa. A aiki na al'ada kodan, an cire shi daga jiki, wato, an tsarkake jini daga gare ta. A wannan dogara ne da fasali daya daga cikin mafi muhimmanci da gwaje-gwaje na koda - samfurin Rehberg. Tare da taimakonsa, an ƙaddamar da filtration na glomerular. Kuma bisa ladaran da aka sani na glomerular, ana nuna lissafin kododin kodan. Amma zamu tattauna game da wannan daga baya.

Creatinine, al'ada ga maza shine 0.044-0.106 mmol / l, da kuma mata - 0.44-0.88 mmol / l, yana ƙaruwa a farko, tare da cutar koda. A cikin wasu dakunan gwaje-gwaje, ana nuna sakamakon binciken a sauran raka'a - a cikin micromoles. Don fassara ƙananan microwaves a cikin micromoles, za a haɓaka narkewar creatinine ta 1000. Misali, al'ada a cikin maza shine 44-106 μmol / l.

Rashin karuwa a cikin halittar halitta yana daya daga cikin manyan alamun rashin cin nasara koda. An hade da gaskiyar cewa a cikin raunuka na ainihin filtration a cikin ƙananan ruba na glomeruli ya rage yawanci.

Duk da haka, ƙwayar cututtuka ba wai kawai dalilin wannan karuwa ba. Dukkan yanayin da cututtuka, wanda a ciki akwai yiwuwar ɓarkewar mahaifa ta phosphate a cikin tsokoki, kuma zai iya ƙara halitta cikin jini zuwa lambobi. Wannan za a iya karfafa ta murdede aiki, hyperthyroidism, abinci mai arziki a cikin furotin, dehydration, acromegaly.

A cikin yanayi tare da lalacewa ga tsoka nama, creatinine ma yakan tashi. Alal misali, mai yawa na tsokar zuciya infarction tare da ƙara creatinine. Ciwon radiation, ƙonewa, ciwo na tsagaita wuta yana faruwa tare da karuwa.

Samun wasu magunguna yana ƙara haɓaka. Yawancin za a iya wucewa idan mai haƙuri ya karbi sulfonamides, barbiturates, maganin rigakafi daga tetracycline da jerin aminoglycoside.

Rashin haɓakar halitta a ƙasa da al'ada ba shi da darajar ƙimar kamar haɓakawa. Zai iya zama saboda rashin amfani da abinci mai gina jiki, yunwa, rashin. Halitta ta rage a kashi na uku na ciki, tare da kumburi, ascites. Ya taimaka wajen rage yawancin cututtukan da ake amfani da su a lokaci mai tsawo na corticosteroids.

Idan an yi la'akari da gazawar koda, kamar yadda aka ambata, ana gwajin gwajin Rheberg.

Lokacin da aka gudanar, haɓakar halitta ta ƙayyade, ƙayyadadden abin da yake cikin jini tare da ƙananan kullun zai iya wucewa sosai, kuma zubar da sininine. Dole ne a tattara babban uba don samfurin Reberg a cikin rana, wannan yana bada cikakkun sakamako fiye da idan an tattara shi a ƙasa da lokaci. Wajibi ne don daidaita ƙimarsa. Ƙananan adadin fitsari ne aka kawo zuwa ga dakin gwaje-gwaje daga ƙwanan yau da kullum, ba lallai ba ne don ɗaukar shi duka. Lokacin tattara tarawa, ya kamata ku guje wa aikin jiki kuma kada ku ci abinci mai gina jiki mai yawa. Jinin yana jin daɗin ciki, da safe. Kullun yau da kullum na hakar creatinine a cikin fitsari shi ne kullum 4.4-17.7 mmol / rana.

Bayan ƙaddamar da halittar halittar jini da fitsari, sanin yawan adadin fitsari na yau da kullum, nauyin da tsawo na mai haƙuri (wannan ya shafi yara), injiniyyar bincike yana ƙididdige darajar ɗakunan jita-jita da kuma bayanan tubular bisa ga tsari na musamman. Tsarin al'ada ga mutanen da suka tsufa: zane-zanen glomerular ga maza - 82-140 ml / min, ga mata - 81-128 ml / min. A al'ada na tubular reabsorption ne 95-99%. Idan aikin na gwanin ya ƙare, waɗannan dabi'u sun karu.