Invisible saba ido Blashko layi a kan jikin mutum

Imperceptible ga tsirara ido alamu a jikin mutum faruwa a ƙarƙashin rinjayar na ciki da kuma exogenous korau abubuwan. Ƙaddara da Pathology kamar yadda Lines Blashko. Melanogenesis bayyana hypopigmentation, da dangantaka da wani rukuni na cututtuka dermatoses. Bayyane benign amfani ga kimiyya. Fahimci qa'ida ta bayyanar da ƙari, yana yiwuwa su hana bayyanar melanoma.

A tarihin nazarin fata cututtuka

Jamus bincike dermatological matsaloli samu Blashko layi a 1901. Suna wakiltar wani juna na pigmentation, irin wannan a cikin tsarin to dukan marasa lafiya. Cutar da aka mai suna bayan da sunan masanin kimiyya, wanda sunan shi Alfred.

Likitan fata kafa dangantaka da ya faru na Pathology X-chromosomes. A lafiya fata imperceptible canje-canje a cikin al'ada taro. A sakamakon da m hijirarsa malanoblastov samuwar bayyane yankin juna. Status of mutated Kwayoyin shi ne dogara a kan jikin ta juyayi breakdowns. Duk da haka, dermatological matsaloli za a iya samu a nakasar gādon da cutar.

Cikin manyan dalilan da sabawa daga cikin 'yan Adam fata

Gane da wadannan dalilai Ilimi Blashko layi a jiki:

• Chimerism - sau da yawa ake magana a kai a matsayin wani yanayin a lokacin da wani mutum tsaye a iri biyu DNA. A daban-daban sa na genes triggers samuwar pigmentation a jiki. Wadannan effects bayyanãwa lalatar da biyu daban-daban jinsi. Sanadin fata Pathology zama wani Fusion na kwan da ya hadu a wani wuri mataki na ciki.
• Human danniya da rashin daidaituwa - wani m tsarin da ake kafa.
• Auren - canje-canje a cikin mutum DNA. Dalilin bayyanar nakasar Pathology zama nevi: depigmented, pigmented, sebaceous, mikakke verrucous kumburi.
• Halitta hadawa DNA a lokacin embryogenesis - masana kimiyya saka tsarin mutum tsokoki: a daya keji sa kwayoyin halitta aka kiyaye. Ko da yake asalin karshen da aka samu daga wani guda zygote.

A yanayi na bayyanar dermatosis

Shi ne frustrating ga sani ba da kalmar "Blashko line" - me ke cewa line? Irin matsalolin sau da yawa samu a jariri jariran, babu fiye da 2% na wanda ake predisposed zuwa bayyanar pathologies. A tsarin da DNA ne da farko ya ƙunshi bayanin cutar. External bayyanar cututtuka bayyana a sakamakon sabawa Endocrinology jiki.

Blashko line halin da uku Kwayoyin a cikin jiki, shi ne tushen da cutar:

• Epidermal keratinocytes - samu Pathology sau da yawa lura a sakamakon chimerism.
• Pigment - located a cikin ƙananan yadudduka na epidermis.
• Profiling iyakar pigment Kwayoyin - kaiwa zuwa wani canji a fata launi, wucewa ta cikin ginshiki membrane cikin saman Layer na dermis. Wannan jiha an kiyaye at m yanayin da samuwar melanoma.

external ãyõyi

A likita adabi bayar da bayanai game da Lines Blashko: cewa shi ne wata cuta daga mutum tsokoki, wanda bayyana kanta a yanayin saukan kasawa a cikin jiki domin rayuwa. Structure ganuwa juna a kan mayar da kashi kama da launi na dabbobi: zebra ko damisa. Yana iya a lura da ultraviolet radiation.

A launi na 'yan Adam fata dogara a kan abu na pigment melanin. An kafa a epidermis kyallen takarda, muhimmi Layer qunshi melanocytes. Sabawa a kan aiwatar da melanogenesis take kaiwa zuwa wani launi canji gani m:

• Hyperpigmentation - m juna da duhu spots a kan fata, suna a fili bambanta daga ainihin inuwa inuwõyi.
• Hypopigmentation - asarar launi na fata Kwayoyin, sakamakon whitish aibobi. Rare Pathology lura ba fiye da 1% na jariri jarirai.

An waje bayyanuwar cutar juna zama V-dimbin yawa, a cikin nau'i na curls ko wavy Lines. Sau da yawa kafa a wadannan sassa na jiki:

• baya.
• a tarnaƙi.
• kafadu.
• shugaban.

diagnosing matsalar

Layin jawo Blashko m lokacin da wani mutum irradiated tare da ultraviolet da haske, amma ga rai na da wuya ya wuce irin wannan jarrabawa. Don karatu da jihar na jiki fara riga a m matakai na cutar. A jariri jarirai, da haske aibobi na hypopigmentation a jiki wuya a ga. The yaro yakan mallaki muhimman canje-canje da fata a cikin 'yan shekaru.

A jihar na Kwayoyin shafi wani sa na chromosomes. Idan yana da matukar daban-daban a cikin m sassan na fata, da sabawa lura a canza launi yadudduka. Saboda haka hypopigmentation iya bayyana da wadannan yanayi:

• M spots - sha'awar kimiyya saboda m Tsarin. A hoto na nuna kiyaye hadaddun siffofi a cikin nau'i na makada, chess Kwayoyin.
• Sarrafa - bayyananna daya tabo a wani takamaiman wuri.
• Jimlace - iya a tare da cututtuka na ciki gabobin.

Me ya sa muke bukatar nazarin zane a kan fata?

Physicians sun koma ga irin zane bincike na kyallen takarda a rikitarwa da bayyane a kan fata. A nan, da babban nuna alama ne da layin Blashko, cutar da ake diddigin ga daidai ganewar asali. Wannan zama da muhimmanci a lokacin da wadannan dermatological matsaloli:

• chimerism.
• mosaicism.
• zoster.
• nevus.
• melanoma.

Complex laushi suna da muhimmanci ne kawai zuwa binciken gefe, domin layman, irin wannan bincike ya ba tukuna kai ga wasu karshe game da cutar. Masana kimiyya shirya ya bayyana manufar da alamu a jikin mutum. Zai yiwu samu zai taimaka wajen kawar da sakamakon wani m fata cuta.