Penicillin maganin rigakafi: jirgin "sihiri harsashi"

Penicillin maganin rigakafi - wani rukuni na antibacterial abubuwa samar da fungal al'adu na HALITTAR Penicillium. Yau, su ne tasiri a chemo- da kwayoyin far. Kamar yadda cephalosporins, penicillin maganin rigakafi suna classified kamar yadda beta-lactam kwayoyi. Tare da wani karfi bactericidal sakamako da kuma wani babban mataki na aiki da gram-tabbatacce kwayoyin cuta, suna da sigar musamman azumi da kuma iko sakamako da aiki a kan pathogenic kwayoyin cuta , yafi a cikin yaduwa zamani.

A halayyar alama na wannan kungiyar da kwayoyi ne da ikon shiga cikin rayayyun tantani kuma suna da wani sakamako a kan neutralizing zaunar cikin wadannan pathogens. Wannan hali a kowa maganin rigakafi-cephalosporins da penicillin, a kwatanta da abin da suka yi da dan kadan fi juriya da beta-lactamases - musamman m enzymes samar da pathogenic kwayoyin.

A gano penicillin, da kokarin da Turanci microbiologist Aleksandra Fleminga a 1929, samar da daya daga cikin mafi girma da juyin juya hali a magani. Sai ya zama zai yiwu zuwa nagarta sosai bi da yawa cututtuka kafin ƙarni aka dauke mutuwa - msl, huhu ƙonewa. Da kuma rawar da penicillin a cikin yakin duniya na biyu a general ne m kuma ma'abutanta raba karatun kimiyya.

Da farko sami ra'ayin abu, wani detrimental sakamako a kan kwayoyin, amma yana da hadari ga mutane, da aka tsara da kuma aiwatar a nuna na XIX-XX ƙarni kafa jiyyar cutar sankara, Paulem Erlihom. Kamar abu, ya aptly jawabin, kamar "sihiri harsashi." Irin wannan sinadaran mahadi aka zarar samu tsakanin Kalam na wasu roba dyes. Kira "jiyyar cutar sankara", sun zama yadu amfani da magani na syphilis. Kuma ko da yake sun inganci da kuma aminci sun kasance da nisa sosai daga zamani penicillins, sun kasance na farko da harbingers na kwayoyin far a cikin zamani view.

Yanzu penicillin maganin rigakafi nuna mafi girma yadda ya dace tare da girmamawa ga anaerobic kwayoyin. Wannan Gaskiya ne, da ake kira superpenitsillinov (azlocillin, piperacillin, mezlocillin da sauransu), kazalika da uku-tsara cephalosporins, wanda ake amfani da akai-akai don rigakafin yiwu postoperative rikitarwa. Yau, m maganin rigakafi penicillin kungiyar amfani da su bi da yara, mata masu ciki, da tsofaffi, marasa lafiya da na koda insufficiency da kuma daban-daban iri m nonspecific epididymitis.

Duk da dukan nasarorin da zamani pharmacology da kuma zumunta kamalar penicillin shirye-shirye mafarki Paulya Erliha na "m sihiri harsashi" da wuya wani abu idan aka aiwatar, kamar yadda har ma da gishiri ne cutarwa a matsanancin yawa. Abin da za mu ce game da irin wannan iko da kuma shan miyagun wayoyi kamar penicillin maganin rigakafi! Side effects na antibacterials data kamata rarraba da yiwuwar wani iri-iri na rashin lafiyan, mai guba halayen da kuma tashin hankali na gastrointestinal aiki.